Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis

Long non-coding RNA HNF1A-AS1 functioned as an oncogene and autophagy promoter in hepatocellular carcinoma through sponging hsa-miR-30b-5p

(2016) Zhiqian Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway

(2016) Han-xiang Zhan et al.   CANCER LETTERS

Long non-coding RNA ROR promotes proliferation, migration and chemoresistance of nasopharyngeal carcinoma

(2016) Li Li et al.   CANCER SCIENCE

Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy

(2016) L. Li et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia-responsive miR-124 and miR-144 reduce hypoxia-induced autophagy and enhance radiosensitivity of prostate cancer cells via suppressing PIM1

(2016) Hao Gu et al.   Cancer Medicine

MiR-124 Regulates Apoptosis and Autophagy Process in MPTP Model of Parkinson's Disease by Targeting to Bim

(2015) Huiqing Wang et al.   BRAIN PATHOLOGY

MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer

(2015) Kohei Taniguchi et al.   CANCER LETTERS

PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma

(2015) Chenggang Li et al.   DIGESTIVE DISEASES AND SCIENCES

Downregulation of ASPP2 in pancreatic cancer cells contributes to increased resistance to gemcitabine through autophagy activation

(2015) Bin Song et al.   Molecular Cancer

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

(2015) Ming-Chen Yang et al.   Molecular Cancer

Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells

(2015) S Calabretta et al.   ONCOGENE

ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer

(2015) Song Gao et al.   Oncotarget

Smarter drugs emerging in pancreatic cancer therapy

(2014) A. Kleger et al.   ANNALS OF ONCOLOGY

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Linc-RNA-RoR acts as a “sponge” against mediation of the differentiation of endometrial cancer stem cells by microRNA-145

(2014) Xi Zhou et al.   GYNECOLOGIC ONCOLOGY

LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis

(2014) P Hou et al.   Cell Death & Disease

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1

(2013) P Wang et al.   ONCOGENE

Interplay between autophagy and apoptosis in pancreatic tumors in response to gemcitabine

(2013) Daniela Laura Papademetrio et al.   Targeted Oncology

miRNA profiling in pancreatic cancer and restoration of chemosensitivity

(2012) Saurabh Singh et al.   CANCER LETTERS

Downregulated MEG3 activates autophagy and increases cell proliferation in bladder cancer

(2012) Liang Ying et al.   Molecular BioSystems

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS