☆ 4.8 Editorial Material

Senescence and Cancer: In the Name of Immunosuppression

CANCER CELL (2016)

Journal

CANCER CELL

Volume 30, Issue 4, Pages 507-508

Publisher

CELL PRESS

DOI: 10.1016/j.ccell.2016.09.015

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Oncology Cell Biology

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Abstract

Senescent cells and cancer cells recruit immunosuppressive myeloid cells. In this issue of Cancer Cell, Eggert et al. report that senescent cells recruit immature myeloid cells (iMCs) through the secretion of the CCL2 cytokine and that these iMCs have pro- or anti-tumorigenic activities, depending on the cellular context.

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