Novel anti-EPHA2 antibody, DS-8895a for cancer treatment

Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein

(2015) N. Koshikawa et al.   CANCER RESEARCH

Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect

(2015) David J. DiLillo et al.   CELL

EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer

(2015) P. D. Dunne et al.   CLINICAL CANCER RESEARCH

Fc-Receptor Interactions Regulate Both Cytotoxic and Immunomodulatory Therapeutic Antibody Effector Functions

(2015) D. J. DiLillo et al.   Cancer Immunology Research

Obinutuzumab (GA101) for the Treatment of Chronic Lymphocytic Leukemia and Other B-Cell Non-Hodgkin's Lymphomas: A Glycoengineered Type II CD20 Antibody

(2015) Valentin Goede et al.   Oncology Research and Treatment

Mogamulizumab and the treatment of CCR4-positive T-cell lymphomas

(2014) Marcus Remer et al.   Immunotherapy

Targeting CD137 enhances the efficacy of cetuximab

(2014) Holbrook E. Kohrt et al.   JOURNAL OF CLINICAL INVESTIGATION

KIR/HLA Interactions Negatively Affect Rituximab- but Not GA101 (Obinutuzumab)-Induced Antibody-Dependent Cellular Cytotoxicity

(2014) G. Terszowski et al.   JOURNAL OF IMMUNOLOGY

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients

(2014) Lin-Fang Wang et al.   ONCOLOGY REPORTS

EPHA2 Is a Mediator of Vemurafenib Resistance and a Novel Therapeutic Target in Melanoma

(2014) B. Miao et al.   Cancer Discovery

The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer

(2014) Ross Stewart et al.   Journal for ImmunoTherapy of Cancer

Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen-Specific T-cell Immunity in Head and Neck Cancer Patients

(2013) R. M. Srivastava et al.   CLINICAL CANCER RESEARCH

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion

(2013) Nami Sugiyama et al.   JOURNAL OF CELL BIOLOGY

Natural Killer Cell Mediated Antibody-Dependent Cellular Cytotoxicity in Tumor Immunotherapy with Therapeutic Antibodies

(2013) Ursula J. E. Seidel et al.   Frontiers in Immunology

GA201 (RG7160): A Novel, Humanized, Glycoengineered Anti-EGFR Antibody with Enhanced ADCC and Superior In Vivo Efficacy Compared with Cetuximab

(2012) C. A. Gerdes et al.   CLINICAL CANCER RESEARCH

Expressions of EphA2 and EphrinA-1 in early squamous cell cervical carcinomas and their relation to prognosis

(2012) Ruth Holm et al.   International Journal of Medical Sciences

Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer

(2012) Holbrook E. Kohrt et al.   JOURNAL OF CLINICAL INVESTIGATION

Marketing approval of mogamulizumab

(2012) Alain Beck et al.   mAbs

Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer

(2011) William M. Merritt et al.   CANCER BIOLOGY & THERAPY

CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies

(2010) H. E. Kohrt et al.   BLOOD

The Metastasis-Associated microRNA miR-516a-3p Is a Novel Therapeutic Target for Inhibiting Peritoneal Dissemination of Human Scirrhous Gastric Cancer

(2010) Yoshifumi Takei et al.   CANCER RESEARCH

Clinical significance of EphA2 expression in squamous-cell carcinoma of the head and neck

(2010) Yong Liu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Expression of the Receptor Tyrosine Kinase EphA2 Is Increased in Smokers and Predicts Poor Survival in Non-Small Cell Lung Cancer

(2009) J. M. Brannan et al.   CLINICAL CANCER RESEARCH

EFNA1 ligand and its receptor EphA2: Potential biomarkers for hepatocellular carcinoma

(2009) Xiang-Dan Cui et al.   INTERNATIONAL JOURNAL OF CANCER

Over-Expression of EphA2 and EphrinA-1 in Human Gastric Adenocarcinoma and Its Prognostic Value for Postoperative Patients

(2008) Wei-Jie Yuan et al.   DIGESTIVE DISEASES AND SCIENCES