Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
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Title
Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 122, Issue 3, Pages 1066-1075
Publisher
American Society for Clinical Investigation
Online
2012-02-13
DOI
10.1172/jci61226
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Note: Only part of the references are listed.- Phase I study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA)
- (2017) M. Sznol et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical benefit of INCB7839, a potent and selective ADAM inhibitor, in combination with trastuzumab in patients with metastatic HER2+ breast cancer.
- (2017) R. C. Newton et al. JOURNAL OF CLINICAL ONCOLOGY
- Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
- (2011) J. Stagg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibitory Fc Receptor Engagement Drives Adjuvant and Anti-Tumor Activities of Agonistic CD40 Antibodies
- (2011) F. Li et al. SCIENCE
- Fc R2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer
- (2010) K. Tamura et al. ANNALS OF ONCOLOGY
- CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies
- (2010) H. E. Kohrt et al. BLOOD
- CD62L expression identifies a unique subset of polyfunctional CD56dim NK cells
- (2010) K. Juelke et al. BLOOD
- Human T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement
- (2010) A. Maniar et al. BLOOD
- CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells
- (2010) H. Narazaki et al. BLOOD
- Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
- (2010) Juan Dubrot et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- 4-1BB Ligand as an Effective Multifunctional Immunomodulator and Antigen Delivery Vehicle for the Development of Therapeutic Cancer Vaccines
- (2010) R. K. Sharma et al. CANCER RESEARCH
- Immobilized MHC class I chain-related protein A synergizes with IL-15 and soluble 4-1BB ligand to expand NK cells with high cytotoxicity ex vivo
- (2010) Weijuan Gong et al. Cellular & Molecular Immunology
- E-cadherin expression on human carcinoma cell affects trastuzumab-mediated antibody-dependent cellular cytotoxicity through killer cell lectin-like receptor G1 on natural killer cells
- (2010) Chisako Yamauchi et al. INTERNATIONAL JOURNAL OF CANCER
- Cellular Adaptive Immune System Plays a Crucial Role in Trastuzumab Clinical Efficacy
- (2010) Filippo Bellati et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of Pertuzumab and Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer That Progressed During Prior Trastuzumab Therapy
- (2010) José Baselga et al. JOURNAL OF CLINICAL ONCOLOGY
- Combination Therapy of Established Tumors by Antibodies Targeting Immune Activating and Suppressing Molecules
- (2010) K. Takeda et al. JOURNAL OF IMMUNOLOGY
- Regulation of Granulocyte and Macrophage Populations of Murine Bone Marrow Cells by G-CSF and CD137 Protein
- (2010) Dongsheng Jiang et al. PLoS One
- Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion
- (2009) R. Houot et al. BLOOD
- CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells
- (2009) T. Baessler et al. BLOOD
- Beyond Trastuzumab: Overcoming Resistance to Targeted HER-2 Therapy in Breast Cancer
- (2009) Philippe Bedard et al. CURRENT CANCER DRUG TARGETS
- In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
- (2009) Oihana Murillo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Understanding the Mechanisms Behind Trastuzumab Therapy for Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
- (2009) Neil L. Spector et al. JOURNAL OF CLINICAL ONCOLOGY
- CD137 Promotes Proliferation and Survival of Human B Cells
- (2009) X. Zhang et al. JOURNAL OF IMMUNOLOGY
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- (2009) Nicolas Acquavella et al. JOURNAL OF IMMUNOTHERAPY
- A phase I trial of paclitaxel and trastuzumab in combination with interleukin-12 in patients with HER2/neu-expressing malignancies
- (2009) T. S. Bekaii-Saab et al. MOLECULAR CANCER THERAPEUTICS
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- (2008) M. A. Caligiuri BLOOD
- Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies
- (2008) W. Lin et al. BLOOD
- A phase II trial of trastuzumab in combination with low-dose interleukin-2 (IL-2) in patients (PTS) with metastatic breast cancer (MBC) who have previously failed trastuzumab
- (2008) Aruna Mani et al. BREAST CANCER RESEARCH AND TREATMENT
- Single-Cell Profiling Identifies Aberrant STAT5 Activation in Myeloid Malignancies with Specific Clinical and Biologic Correlates
- (2008) Nikesh Kotecha et al. CANCER CELL
- Expression of t-DARPP Mediates Trastuzumab Resistance in Breast Cancer Cells
- (2008) A. Belkhiri et al. CLINICAL CANCER RESEARCH
- Therapeutic Antitumor Efficacy of Anti-CD137 Agonistic Monoclonal Antibody in Mouse Models of Myeloma
- (2008) O. Murillo et al. CLINICAL CANCER RESEARCH
- Current perspective – Trastuzumab
- (2008) Peter S. Hall et al. EUROPEAN JOURNAL OF CANCER
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- (2008) Antonino Musolino et al. JOURNAL OF CLINICAL ONCOLOGY
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