Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells

Semblance: An empirical similarity kernel on probability spaces

(2019) Divyansh Agarwal et al.   Science Advances

Associations of Simian Immunodeficiency Virus (SIV)-Specific Follicular CD8+T Cells with Other Follicular T Cells Suggest Complex Contributions to SIV Viremia Control

(2018) Mohammad Arif Rahman et al.   JOURNAL OF IMMUNOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease

(2018) Marcus Buggert et al.   PLoS Pathogens

Defining total-body AIDS-virus burden with implications for curative strategies

(2017) Jacob D Estes et al.   NATURE MEDICINE

Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals

(2017) Johanna Tauriainen et al.   Scientific Reports

HIV-Specific CD8 + T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue

(2017) Morgan A. Reuter et al.   Cell Reports

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

ROTS: An R package for reproducibility-optimized statistical testing

(2017) Tomi Suomi et al.   PLoS Computational Biology

Multiple Origins of Virus Persistence during Natural Control of HIV Infection

(2016) Eli A. Boritz et al.   CELL

CD8 + Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

(2016) Emily K. Cartwright et al.   IMMUNITY

Interleukin 32: a novel player in the control of infectious diseases

(2016) Fátima Ribeiro-Dias et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8 + Cells In Vivo

(2016) Shengbin Li et al.   JOURNAL OF VIROLOGY

Identification of innate immune antiretroviral factors during in vivo and in vitro exposure to HIV-1

(2016) Wildeman Zapata et al.   MICROBES AND INFECTION

Kill

(2016) Lydie Trautmann   Current Opinion in HIV and AIDS

Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs

(2016) Heng Giap Woon et al.   PLoS Pathogens

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

(2015) Yoshinori Fukazawa et al.   NATURE MEDICINE

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Compartmentalization of Simian Immunodeficiency Virus Replication within Secondary Lymphoid Tissues of Rhesus Macaques Is Linked to Disease Stage and Inversely Related to Localization of Virus-Specific CTL

(2014) Elizabeth Connick et al.   JOURNAL OF IMMUNOLOGY

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

(2014) Alexandra Schuetz et al.   PLoS Pathogens

T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection

(2014) Marcus Buggert et al.   PLoS Pathogens

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis

(2012) Florent Carrette et al.   SEMINARS IN IMMUNOLOGY

HIV-specific CD8+ T-cell proliferation is prospectively associated with delayed disease progression

(2011) Lyle R McKinnon et al.   IMMUNOLOGY AND CELL BIOLOGY

HIV-1 Continues To Replicate and Evolve in Patients with Natural Control of HIV Infection

(2010) H. Mens et al.   JOURNAL OF VIROLOGY

Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus

(2010) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Ex vivo T cell–based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses

(2010) Asier Sáez-Cirión et al.   Nature Protocols

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

(2010) Nichole R. Klatt et al.   PLoS Pathogens

In Vivo CD8+ T-Cell Suppression of SIV Viremia Is Not Mediated by CTL Clearance of Productively Infected Cells

(2010) Joseph K. Wong et al.   PLoS Pathogens

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY