TDRG1 regulates chemosensitivity of seminoma TCam-2 cells to cisplatin via PI3K/Akt/mTOR signaling pathway and mitochondria-mediated apoptotic pathway

TDRG1 functions in testicular seminoma are dependent on the PI3K/Akt/mTOR signaling pathway

(2016) Yuxin Tang et al.   OncoTargets and Therapy

Inhibin-α, E-cadherin, calretinin and Ki-67 antigen in the immunohistochemical evaluation of canine and human testicular neoplasms

(2015) Rafal Ciaputa et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Expression and Localization of Testis Developmental Related Gene 1 (TDRG1) in Human Spermatozoa

(2015) Houyang Chen et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Targeted therapies in germ cell tumors

(2015) Christian M. Squillante et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

MK2206 potentiates cisplatin-induced cytotoxicity and apoptosis through an interaction of inactivated Akt signaling pathway

(2015) Dingqi Sun et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

In vitro study on shRNA-mediated reduction of testis developmental related gene 1 expression and its effects on the proliferation, invasion and apoptosis of NTERA-2 cells

(2015) YU GAN et al.   Oncology Letters

REV3L, a Promising Target in Regulating the Chemosensitivity of Cervical Cancer Cells

(2015) Li Yang et al.   PLoS One

Radiotherapy or chemotherapy for clinical stage IIA and IIB seminoma: a systematic review and meta-analysis of patient outcomes†

(2014) P. Giannatempo et al.   ANNALS OF ONCOLOGY

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Testicular Cancer — Discoveries and Updates

(2014) Nasser H. Hanna et al.   NEW ENGLAND JOURNAL OF MEDICINE

The chemosensitivity of testicular germ cell tumors

(2014) Ioannis A. Voutsadakis   CELLULAR ONCOLOGY

The PDGFRβ–AKT Pathway Contributes to CDDP-Acquired Resistance in Testicular Germ Cell Tumors

(2013) M. Juliachs et al.   CLINICAL CANCER RESEARCH

Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data

(2013) Charlotte Le Cornet et al.   EUROPEAN JOURNAL OF CANCER

Klotho Sensitizes Human Lung Cancer Cell Line to Cisplatin via PI3k/Akt Pathway

(2013) Yan Wang et al.   PLoS One

Establishment and Characterization of a new Human Extragonadal Germ Cell Line, SEM-1, and its Comparison With TCam-2 and JKT-1

(2013) Sarah M. Russell et al.   UROLOGY

Testicular germ cell tumours

(2013) A. Horwich et al.   BMJ-British Medical Journal

Silencing p110β prevents rapid depletion of nuclear pAkt

(2011) Zhi-wei Ye et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Increased expression of transcription factor TFAP2α correlates with chemosensitivity in advanced bladder cancer

(2011) Iver Nordentoft et al.   BMC CANCER

Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/BclXL-regulated mitochondrial apoptotic pathway

(2011) Ke-Wu Zeng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

mTOR Kinase Domain Phosphorylation Promotes mTORC1 Signaling, Cell Growth, and Cell Cycle Progression

(2011) B. Ekim et al.   MOLECULAR AND CELLULAR BIOLOGY

Complications associated with chemotherapy in testicular cancer management

(2011) Chunkit Fung et al.   Nature Reviews Urology

Characterization of a Novel Human Testis-Specific Gene: Testis Developmental Related Gene 1 (TDRG1)

(2011) Xianzhen Jiang et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance

(2010) Hendrik Wermann et al.   JOURNAL OF PATHOLOGY

Aberration of the PI3K/AKT/mTOR signaling in epithelial ovarian cancer and its implication in cisplatin-based chemotherapy

(2009) Hai-Yan Zhang et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology