Foldamer-templated catalysis of macrocycle formation

The importance of synthetic chemistry in the pharmaceutical industry

(2019) Kevin R. Campos et al.   SCIENCE

Silylarene Hydrogenation: A Strategic Approach that Enables Direct Access to Versatile Silylated Saturated Carbo- and Heterocycles

(2018) Mario P. Wiesenfeldt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

At Long Last: Olefin Metathesis Macrocyclization at High Concentration

(2018) Adrian Sytniczuk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation

(2018) Zebediah C. Girvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetically E-selective macrocyclic ring-closing metathesis

(2017) Xiao Shen et al.   NATURE

Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions

(2017) Yongho Park et al.   SCIENCE

A multifunctional catalyst that stereoselectively assembles prodrugs

(2017) Daniel A. DiRocco et al.   SCIENCE

Iron(III)-catalysed carbonyl–olefin metathesis

(2016) Jacob R. Ludwig et al.   NATURE

Intramolecular hydroalkoxylation catalyzed inside a self-assembled cavity of an enzyme-like host structure

(2015) L. Catti et al.   CHEMICAL COMMUNICATIONS

Macrocyclization Reactions: The Importance of Conformational, Configurational, and Template-Induced Preorganization

(2015) Vicente Martí-Centelles et al.   CHEMICAL REVIEWS

An aqueous molecular tube with polyaromatic frameworks capable of binding fluorescent dyes

(2015) Keita Hagiwara et al.   Chemical Science

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Comparison of silver and molybdenum microfocus X-ray sources for single-crystal structure determination

(2015) Lennard Krause et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor

(2014) Åsa Rosenquist et al.   JOURNAL OF MEDICINAL CHEMISTRY

How proteins bind macrocycles

(2014) Elizabeth A Villar et al.   Nature Chemical Biology

Stereoselective Access to Z and E Macrocycles by Ruthenium-Catalyzed Z-Selective Ring-Closing Metathesis and Ethenolysis

(2012) Vanessa M. Marx et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Replacing Conventional Carbon Nucleophiles with Electrophiles: Nickel-Catalyzed Reductive Alkylation of Aryl Bromides and Chlorides

(2012) Daniel A. Everson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strained cyclophane natural products: Macrocyclization at its limits

(2012) Tanja Gulder et al.   NATURAL PRODUCT REPORTS

Conjugated Macrocycles: Concepts and Applications

(2011) Masahiko Iyoda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis

(2011) Miao Yu et al.   NATURE

Catalytic Z-selective olefin cross-metathesis for natural product synthesis

(2011) Simon J. Meek et al.   NATURE

Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

(2010) John A. McCauley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Detection and Analysis of Chimeric Tertiary Structures by Backbone Thioester Exchange: Packing of an α Helix against an α/β-Peptide Helix

(2009) Joshua L. Price et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric catalysis with chiral primary amine-based organocatalysts

(2009) Li-Wen Xu et al.   CHEMICAL COMMUNICATIONS

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystallographic Characterization of Helical Secondary Structures in 2:1 and 1:2 α/β-Peptides

(2009) Soo Hyuk Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Etnangien

(2009) Pengfei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY