Silylarene Hydrogenation: A Strategic Approach that Enables Direct Access to Versatile Silylated Saturated Carbo- and Heterocycles

Rare-Earth-Catalyzed Regioselective Hydrosilylation of Aryl-Substituted Internal Alkenes

(2018) Jinxi Liu et al.   ACS Catalysis

Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds

(2017) Remya Ramesh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Cross-Coupling of Silyl Electrophiles with Alkylzinc Halides: A Silyl-Negishi Reaction

(2017) Andrew P. Cinderella et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium–NHC–Diamine Catalyzed Enantioselective Hydrogenation of Isocoumarins

(2017) Wei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations

(2017) Yifan Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogenation of fluoroarenes: Direct access to all-cis-(multi)fluorinated cycloalkanes

(2017) Mario P. Wiesenfeldt et al.   SCIENCE

Palladium-Catalyzed Cross-Coupling of Monochlorosilanes and Grignard Reagents

(2017) Bojan Vulovic et al.   ACS Catalysis

Electrophilic Aromatic Substitution with Silicon Electrophiles: Catalytic Friedel-Crafts C−H Silylation

(2016) Susanne Bähr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Cross-Coupling of Silicon Pronucleophiles with Unactivated Alkyl Electrophiles Coupled with Radical Cyclization

(2016) Weichao Xue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silicon–Carbon Bond Formation via Nickel-Catalyzed Cross-Coupling of Silicon Nucleophiles with Unactivated Secondary and Tertiary Alkyl Electrophiles

(2016) Crystal K. Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbenes in Asymmetric Hydrogenation

(2016) Dongbing Zhao et al.   ACS Catalysis

Asymmetric Ruthenium-Catalyzed Hydrogenation of 2,6-Disubstituted 1,5-Naphthyridines: Access to Chiral 1,5-Diaza-cis-Decalins

(2015) Jianwei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Silylation of Unactivated C–H Bonds

(2015) Chen Cheng et al.   CHEMICAL REVIEWS

Highly Selective Hydrogenation of Aromatic Ketones and Phenols Enabled by Cyclic (Amino)(alkyl)carbene Rhodium Complexes

(2015) Yu Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst

(2015) Anton A. Toutov et al.   NATURE

Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst

(2014) Mingxin Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Environmental Chemistry of Organosiloxanes

(2014) Christoph Rücker et al.   CHEMICAL REVIEWS

Diastereoconvergent Negishi Cross-Coupling Using Functionalized Cyclohexylzinc Reagents

(2014) Kohei Moriya et al.   ORGANIC LETTERS

Asymmetric Hydrogenation of Isoquinolinium Salts Catalyzed by Chiral Iridium Complexes: Direct Synthesis for Optically Active 1,2,3,4-Tetrahydroisoquinolines

(2013) Atsuhiro Iimuro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two- and Three-dimensional Rings in Drugs

(2013) Matteo Aldeghi et al.   Chemical Biology & Drug Design

Sila-rhubafuran and Derivatives: Synthesis and Olfactory Characterization of Novel Silicon-Containing Odorants

(2013) Bettina Förster et al.   ORGANOMETALLICS

Catalytic Asymmetric Hydrogenation of Naphthalenes

(2012) Ryoichi Kuwano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organosilicon Molecules with Medicinal Applications

(2012) Annaliese K. Franz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rhodium-Catalyzed Carbon–Silicon Bond Activation for Synthesis of Benzosilole Derivatives

(2012) Masahiro Onoe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Controlled Highly Regioselective and Asymmetric Hydrogenation of Quinoxalines Catalyzed by Ruthenium N-Heterocyclic Carbene Complexes

(2011) Slawomir Urban et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

Palladium-catalysed cross-coupling of organosilicon reagents

(2011) Hannah F. Sore et al.   CHEMICAL SOCIETY REVIEWS

What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

(2011) W. Patrick Walters et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Facile Stereoselective Biocatalytic Route to the Precursor of Woody Acetate

(2011) Gareth Brown et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Rhodium(I)-Catalyzed 1,4-Silicon Shift of Unactivated Silanes from Aryl to Alkyl: Enantioselective Synthesis of Indanol Derivatives

(2010) Tobias Seiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Synthesis of Silanol

(2008) Kazunobu Igawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery and synthetic applications of novel silicon-carbon bond cleavage reactions based on the coordination number change of organosilicon compounds

(2008) Kohei TAMAO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES