Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells

Prospective Randomized Biomarker Study of Metformin and Lifestyle Intervention for Prevention in Obese Women at Increased Risk for Endometrial Cancer

(2018) Melinda S. Yates et al.   Cancer Prevention Research

Synergistic effect of metformin and medroxyprogesterone 17‑acetate on the development of endometrial cancer

(2018) Nan Mu et al.   ONCOLOGY REPORTS

Effects of Metformin on Cellular Proliferation and Steroid Hormone Receptors in Patient-Derived, Low-Grade Endometrial Cancer Cell Lines

(2018) Gretchen Collins et al.   Reproductive Sciences

Metformin as a Therapeutic Target in Endometrial Cancers

(2018) Teresa Y. Lee et al.   Frontiers in Oncology

Role of metformin in inhibiting estrogen-induced proliferation and regulating ERα and ERβ expression in human endometrial cancer cells

(2017) Jingbo Zhang et al.   Oncology Letters

Metformin use and survival outcomes in endometrial cancer: a systematic review and meta-analysis

(2017) Weimin Xie et al.   Oncotarget

Measuring the biological effect of presurgical metformin treatment in endometrial cancer

(2016) V N Sivalingam et al.   BRITISH JOURNAL OF CANCER

Identifying High-Risk Women for Endometrial Cancer Prevention Strategies: Proposal of an Endometrial Cancer Risk Prediction Model

(2016) Sarah J. Kitson et al.   Cancer Prevention Research

Prospective evaluation of the molecular effects of metformin on the endometrium in women with newly diagnosed endometrial cancer: A window of opportunity study

(2016) Pamela T. Soliman et al.   GYNECOLOGIC ONCOLOGY

Insulin-Like Growth Factor 1/Mammalian Target of Rapamycin and AMP-Activated Protein Kinase Signaling Involved in the Effects of Metformin in the Human Endometrial Cancer

(2016) Dongge Cai et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Inverse Relationship between Progesterone Receptor and Myc in Endometrial Cancer

(2016) Tamar Kavlashvili et al.   PLoS One

Repurposing old drugs to chemoprevention: the case of metformin

(2016) Brandy M. Heckman-Stoddard et al.   SEMINARS IN ONCOLOGY

Metformin in Cancer Treatment and Prevention

(2015) Daniel R. Morales et al.   Annual Review of Medicine

Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling

(2015) Adam R. Brown et al.   CARCINOGENESIS

Metformin Action: Concentrations Matter

(2015) Ling He et al.   Cell Metabolism

Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells

(2015) Maria Theresa E. Montales et al.   Genes and Nutrition

Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality

(2015) Emily Jane Gallagher et al.   PHYSIOLOGICAL REVIEWS

PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression

(2015) Simona Citro et al.   Journal of Molecular Cell Biology

Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells

(2015) Maria Theresa E. Montales et al.   Genes and Nutrition

Effects of metformin on endometrial cancer cell growth in vivo: A preoperative prospective trial

(2014) Akira Mitsuhashi et al.   CANCER

Transcription factor KLF9 suppresses the growth of hepatocellular carcinoma cells in vivo and positively regulates p53 expression

(2014) Jiabin Sun et al.   CANCER LETTERS

Anti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer

(2014) Ido Laskov et al.   GYNECOLOGIC ONCOLOGY

Krüppel-like factor 4 mediates anti-proliferative effects of progesterone with G0/G1 arrest in human endometrial epithelial cells

(2014) Y. Shimizu et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Metformin—mode of action and clinical implications for diabetes and cancer

(2014) Ida Pernicova et al.   Nature Reviews Endocrinology

Metformin and Gynecologic Cancers

(2014) Jessica E. Stine et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Rapid Estrogen Signaling Negatively Regulates PTEN Activity Through Phosphorylation in Endometrial Cancer Cells

(2014) Melanie M. Scully et al.   Hormones & Cancer

Phosphorylation: a fundamental regulator of steroid receptor action

(2013) Lindsey S. Treviño et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Does Metformin affect ER, PR, IGF-1R, β-catenin and PAX-2 expression in women with diabetes mellitus and endometrial cancer?

(2013) Anna Markowska et al.   Diabetology & Metabolic Syndrome

DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination

(2012) Christopher Korch et al.   GYNECOLOGIC ONCOLOGY

Krüppel-Like Factor 9 and Progesterone Receptor Coregulation of Decidualizing Endometrial Stromal Cells: Implications for the Pathogenesis of Endometriosis

(2012) John Mark P. Pabona et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects

(2012) M A Pierotti et al.   ONCOGENE

Understanding obesity and endometrial cancer risk: opportunities for prevention

(2011) Rosemarie E. Schmandt et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Krüppel-Like Factor 9 Loss-of-Expression in Human Endometrial Carcinoma Links Altered Expression of Growth-Regulatory Genes with Aberrant Proliferative Response to Estrogen1

(2011) Christian D. Simmons et al.   BIOLOGY OF REPRODUCTION

Metformin and cancer: Doses, mechanisms and the dandelion and hormetic phenomena

(2010) Begoña Martin-Castillo et al.   CELL CYCLE

Metformin promotes progesterone receptor expression via inhibition of mammalian target of rapamycin (mTOR) in endometrial cancer cells

(2010) Ya Xie et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY