Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing
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Title
Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 6, Pages 3123-3134
Publisher
Proceedings of the National Academy of Sciences
Online
2020-01-30
DOI
10.1073/pnas.1918611117
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Note: Only part of the references are listed.- The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
- (2019) Daniel N. Weinberg et al. NATURE
- A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing
- (2019) Allegra A. Petti et al. Nature Communications
- Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo
- (2018) Mira Jeong et al. Cell Reports
- Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies
- (2017) Christopher B. Cole et al. JOURNAL OF CLINICAL INVESTIGATION
- Acute myeloid leukaemia in a case with Tatton-Brown-Rahman syndrome: the peculiarDNMT3AR882 mutation
- (2017) Iris H I M Hollink et al. JOURNAL OF MEDICAL GENETICS
- Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers
- (2017) Jacob L. Glass et al. Cancer Discovery
- Acute myeloid leukemia-associatedDNMT3Ap.Arg882His mutation in a patient with Tatton-Brown-Rahman overgrowth syndrome as a constitutional mutation
- (2016) Rika Kosaki et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation
- (2016) Matthias Farlik et al. Cell Stem Cell
- DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells
- (2016) Christopher E. Duymich et al. Nature Communications
- Haemopedia: An Expression Atlas of Murine Hematopoietic Cells
- (2016) Carolyn A. de Graaf et al. Stem Cell Reports
- Accelerated apoptosis of peripheral blood monocytes in Cebpb -deficient mice
- (2015) Akihiro Tamura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
- (2015) D. P. Steensma et al. BLOOD
- metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data
- (2015) Frank Jühling et al. GENOME RESEARCH
- Regulation of myelopoiesis by the transcription factor IRF8
- (2015) Tomohiko Tamura et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
- (2015) Mihaela Pertea et al. NATURE BIOTECHNOLOGY
- PANTHER version 10: expanded protein families and functions, and analysis tools
- (2015) Huaiyu Mi et al. NUCLEIC ACIDS RESEARCH
- Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
- (2014) A. Mayle et al. BLOOD
- The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers
- (2014) David A. Russler-Germain et al. CANCER CELL
- Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
- (2014) Xiaojing Yang et al. CANCER CELL
- Dnmt3a and Dnmt3b Have Overlapping and Distinct Functions in Hematopoietic Stem Cells
- (2014) Grant A. Challen et al. Cell Stem Cell
- Age-related mutations associated with clonal hematopoietic expansion and malignancies
- (2014) Mingchao Xie et al. NATURE MEDICINE
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
- (2014) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Large conserved domains of low DNA methylation maintained by Dnmt3a
- (2013) Mira Jeong et al. NATURE GENETICS
- Large-scale gene function analysis with the PANTHER classification system
- (2013) Huaiyu Mi et al. Nature Protocols
- Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice
- (2013) Megumi Takiguchi et al. PLoS One
- Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia
- (2012) A. F. T. Ribeiro et al. BLOOD
- The Origin and Evolution of Mutations in Acute Myeloid Leukemia
- (2012) John S. Welch et al. CELL
- Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
- (2012) Marta Kulis et al. NATURE GENETICS
- BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions
- (2012) Kasper D Hansen et al. GENOME BIOLOGY
- Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia
- (2011) Y. Shen et al. BLOOD
- Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications
- (2011) Guido Marcucci et al. JOURNAL OF CLINICAL ONCOLOGY
- Incidence and Prognostic Influence of DNMT3A Mutations in Acute Myeloid Leukemia
- (2011) Felicitas Thol et al. JOURNAL OF CLINICAL ONCOLOGY
- Dnmt3a is essential for hematopoietic stem cell differentiation
- (2011) Grant A Challen et al. NATURE GENETICS
- Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
- (2011) Xiao-Jing Yan et al. NATURE GENETICS
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- DNMT3AMutations in Acute Myeloid Leukemia
- (2010) Timothy J. Ley et al. NEW ENGLAND JOURNAL OF MEDICINE
- A scaling normalization method for differential expression analysis of RNA-seq data
- (2010) Mark D Robinson et al. GENOME BIOLOGY
- TopHat: discovering splice junctions with RNA-Seq
- (2009) Cole Trapnell et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Rethinking how DNA methylation patterns are maintained
- (2009) Peter A. Jones et al. NATURE REVIEWS GENETICS
- The human gamma-glutamyltransferase gene family
- (2008) Nora Heisterkamp et al. HUMAN GENETICS
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