Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination

MMP7 cleaves remyelination-impairing fibronectin aggregates and its expression is reduced in chronic multiple sclerosis lesions

(2018) Peng Wang et al.   GLIA

TIMP-1 Promotes Oligodendrocyte Differentiation Through Receptor-Mediated Signaling

(2018) Alexandra M. Nicaise et al.   MOLECULAR NEUROBIOLOGY

Oligodendroglia: metabolic supporters of neurons

(2017) Thomas Philips et al.   JOURNAL OF CLINICAL INVESTIGATION

The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies

(2017) AdrianaOctaviana Dulamea   Neural Regeneration Research

Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance

(2017) Keying Zhu et al.   Frontiers in Neuroscience

Multiple sclerosis: experimental models and reality

(2016) Hans Lassmann et al.   ACTA NEUROPATHOLOGICA

Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3

(2016) Stephanie M. Davis et al.   MOLECULAR NEUROBIOLOGY

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF)

(2015) Sonja Rittchen et al.   BIOMATERIALS

Oncostatin M protects against demyelination by inducing a protective microglial phenotype

(2015) Kris Janssens et al.   GLIA

TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice

(2015) J. Kobuch et al.   HAEMATOLOGICA

Activation Status of Human Microglia Is Dependent on Lesion Formation Stage and Remyelination in Multiple Sclerosis

(2015) Laura A.N. Peferoen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice

(2015) J. Kobuch et al.   HAEMATOLOGICA

Analysis of IL-6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M

(2014) Meng-Ping Hsu et al.   GLIA

The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination

(2014) Josephine M. J. Stoffels et al.   GLIA

Oncostatin M Reduces Lesion Size and Promotes Functional Recovery and Neurite Outgrowth After Spinal Cord Injury

(2014) Helena Slaets et al.   MOLECULAR NEUROBIOLOGY

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

(2014) Masayuki Shimoda et al.   NATURE CELL BIOLOGY

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Minocycline reduces remyelination by suppressing ciliary neurotrophic factor expression after cuprizone-induced demyelination

(2013) Tatsuhide Tanaka et al.   JOURNAL OF NEUROCHEMISTRY

Myelination

(2012) Susan C. Barnett et al.   NEUROSCIENTIST

Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia

(2012) Ashutosh et al.   Cell Death & Disease

Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6

(2011) Wenda Gao et al.   CELL CYCLE

Matrix Metalloproteinases and Their Tissue Inhibitors in Cuprizone-Induced Demyelination and Remyelination of Brain White and Gray Matter

(2011) Jelena Škuljec et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Astrocytic Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Promotes Oligodendrocyte Differentiation and Enhances CNS Myelination

(2011) C. S. Moore et al.   JOURNAL OF NEUROSCIENCE

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Interleukin-6-type cytokines in neuroprotection and neuromodulation: oncostatin M, but not leukemia inhibitory factor, requires neuronal adenosine A1 receptor function

(2010) Shamsudheen Moidunny et al.   JOURNAL OF NEUROCHEMISTRY

How factors secreted from astrocytes impact myelin repair

(2010) Craig S. Moore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Modulation of CD4+ T Lymphocyte Lineage Outcomes with Targeted, Nanoparticle-Mediated Cytokine Delivery

(2010) Jason Park et al.   MOLECULAR PHARMACEUTICS

CNS-targeted LIF Expression Improves Therapeutic Efficacy and Limits Autoimmune-mediated Demyelination in a Model of Multiple Sclerosis

(2010) Helena Slaets et al.   MOLECULAR THERAPY

Remyelination protects axons from demyelination-associated axon degeneration

(2008) K. A. Irvine et al.   BRAIN

17β-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice

(2008) Peter Acs et al.   GLIA

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE