On the possible origin of protein homochirality, structure, and biochemical function

Peptide ligation by chemoselective aminonitrile coupling in water

(2019) Pierre Canavelli et al.   NATURE

From ancestral peptides to designed proteins

(2018) Vikram Alva et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Bird’s-Eye View of Enzyme Evolution: Chemical, Physicochemical, and Physiological Considerations

(2018) Dan Davidi et al.   CHEMICAL REVIEWS

Protocells and RNA Self-Replication

(2018) Gerald F. Joyce et al.   Cold Spring Harbor Perspectives in Biology

BRENDA in 2019: a European ELIXIR core data resource

(2018) Lisa Jeske et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

The Central Symbiosis of Molecular Biology: Molecules in Mutualism

(2017) Kathryn A. Lanier et al.   JOURNAL OF MOLECULAR EVOLUTION

Foldamer hypothesis for the growth and sequence differentiation of prebiotic polymers

(2017) Elizaveta Guseva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical assessment of methods of protein structure prediction (CASP)-Round XII

(2017) John Moult et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

On the importance of composite protein multiple ligand interactions in protein pockets

(2016) Sam Tonddast-Navaei et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

OUP accepted manuscript

(2016)   NUCLEIC ACIDS RESEARCH

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Meteoritic Amino Acids: Diversity in Compositions Reflects Parent Body Histories

(2016) Jamie E. Elsila et al.   ACS Central Science

Implications of the small number of distinct ligand binding pockets in proteins for drug discovery, evolution and biochemical function

(2015) Jeffrey Skolnick et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

On the Role of Physics and Evolution in Dictating Protein Structure and Function

(2014) Jeffrey Skolnick et al.   ISRAEL JOURNAL OF CHEMISTRY

Carl Woese's vision of cellular evolution and the domains of life

(2014) Eugene V Koonin   RNA Biology

4′-O-substitutions determine selectivity of aminoglycoside antibiotics

(2014) Déborah Perez-Fernandez et al.   Nature Communications

Computational Enzyme Design

(2013) Gert Kiss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

APoc: large-scale identification of similar protein pockets

(2013) Mu Gao et al.   BIOINFORMATICS

The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes

(2013) Nicholas Furnham et al.   NUCLEIC ACIDS RESEARCH

Interplay of physics and evolution in the likely origin of protein biochemical function

(2013) Jeffrey Skolnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring Fold Space Preferences of New-born and Ancient Protein Superfamilies

(2013) Hannah Edwards et al.   PLoS Computational Biology

A Comprehensive Survey of Small-Molecule Binding Pockets in Proteins

(2013) Mu Gao et al.   PLoS Computational Biology

Autocatalytic Replication and Homochirality in Biopolymers: Is Homochirality a Requirement of Life or a Result of It?

(2012) Meng Wu et al.   ASTROBIOLOGY

Ribosomal proteins: Structure, function, and evolution

(2012) A. V. Korobeinikova et al.   BIOCHEMISTRY-MOSCOW

Further Evidence for the Likely Completeness of the Library of Solved Single Domain Protein Structures

(2012) Jeffrey Skolnick et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Divergence and Convergence in Enzyme Evolution

(2011) Michael Y. Galperin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution

(2011) Olga Khersonsky et al.   JOURNAL OF MOLECULAR BIOLOGY

Why not consider a spherical protein? Implications of backbone hydrogen bonding for protein structure and function

(2011) Michal Brylinski et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Functional Capabilities of the Earliest Peptides and the Emergence of Life

(2011) E. James Milner-White et al.   Genes

How significant is a protein structure similarity with TM-score = 0.5?

(2010) Jinrui Xu et al.   BIOINFORMATICS

Editorial of the PCCP themed issue

(2010) Seong Keun Kim et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The Origins of the RNA World

(2010) M. P. Robertson et al.   Cold Spring Harbor Perspectives in Biology

Enhanced Amine and Amino Acid Analysis Using Pacific Blue and the Mars Organic Analyzer Microchip Capillary Electrophoresis System

(2009) Thomas N. Chiesl et al.   ANALYTICAL CHEMISTRY

Fr-TM-align: a new protein structural alignment method based on fragment alignments and the TM-score

(2009) Shashi Pandit et al.   BMC BIOINFORMATICS

The continuity of protein structure space is an intrinsic property of proteins

(2009) J. Skolnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved prediction of protein side-chain conformations with SCWRL4

(2009) Georgii G. Krivov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin

(2008) Joerg M. Harms et al.   MOLECULAR CELL

Distance-scaled, finite ideal-gas reference state improves structure-derived potentials of mean force for structure selection and stability prediction

(2002) Hongyi Zhou et al.   PROTEIN SCIENCE