Implications of the small number of distinct ligand binding pockets in proteins for drug discovery, evolution and biochemical function

Authors

Keywords

Ligand binding pockets, Virtual ligand screening, Kinases, proteases, phosphatases, Drug repurposing, Drug side effects

Journal

Volume 25, Issue 6, Pages 1163-1170

Publisher

Elsevier BV

Online

2015-02-04

DOI

10.1016/j.bmcl.2015.01.059

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