Hydrocarboxylic acid receptor 1 in BAT regulates glucose uptake in mice fed a high-fat diet

Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice

(2019) Cristina Miralpeix et al.   JOURNAL OF LIPID RESEARCH

The lactate receptor HCAR1 modulates neuronal network activity through the activation of Gα and Gβɣ subunits

(2019) Haíssa de Castro Abrantes et al.   JOURNAL OF NEUROSCIENCE

Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

(2018) Sally Winther et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides

(2018) Graeme Weir et al.   Cell Metabolism

RalA controls glucose homeostasis by regulating glucose uptake in brown fat

(2018) Yuliya Skorobogatko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice

(2018) Jae Hoon Jeong et al.   Scientific Reports

Dissociation Between Brown Adipose Tissue 18 F-FDG Uptake and Thermogenesis in Uncoupling Protein 1–Deficient Mice

(2017) Mohammed K. Hankir et al.   JOURNAL OF NUCLEAR MEDICINE

Hydroxy-Carboxylic Acid Receptor Actions in Metabolism

(2017) Stefan Offermanns   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Adipocyte lipolysis and insulin resistance

(2016) Pauline Morigny et al.   BIOCHIMIE

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue

(2016) V. Albert et al.   EMBO Molecular Medicine

Brown adipose tissue as a secretory organ

(2016) Francesc Villarroya et al.   Nature Reviews Endocrinology

Induction of triglyceride accumulation and mitochondrial maintenance in muscle cells by lactate

(2016) Jingquan Sun et al.   Scientific Reports

Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

(2015) Qin Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Selective Impairment of Glucose but Not Fatty Acid or Oxidative Metabolism in Brown Adipose Tissue of Subjects With Type 2 Diabetes

(2015) Denis P. Blondin et al.   DIABETES

Diet-induced obesity causes insulin resistance in mouse brown adipose tissue

(2015) Carla Roberts-Toler et al.   Obesity

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

Brown fat fuel utilization and thermogenesis

(2014) Kristy L. Townsend et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of high fat diet on GPR109A and GPR81 gene expression

(2012) Desiree Wanders et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans

(2012) Véronique Ouellet et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Female Mice are Protected against High-Fat Diet Induced Metabolic Syndrome and Increase the Regulatory T Cell Population in Adipose Tissue

(2012) Ulrika S. Pettersson et al.   PLoS One

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects

(2012) Curt A. Dvorak et al.   ACS Medicinal Chemistry Letters

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

(2011) Janne Orava et al.   Cell Metabolism

Gender Difference in Proteome of Brown Adipose Tissues between Male and Female Rats Exposed to a High Fat Diet

(2011) Duk Kwon Choi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Estrogen modulates abdominal adiposity and protects female mice from obesity and impaired glucose tolerance

(2011) Renee E. Stubbins et al.   EUROPEAN JOURNAL OF NUTRITION

Inflammation inhibits GPR81 expression in adipose tissue

(2011) Kenneth R. Feingold et al.   INFLAMMATION RESEARCH

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Impact of Age on the Relationships of Brown Adipose Tissue With Sex and Adiposity in Humans

(2010) C. Pfannenberg et al.   DIABETES

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sex Differences in High-fat Diet-induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

(2009) Ling-Ling Hwang et al.   Obesity

Sex differences in the regulation of body weight

(2009) H. Shi et al.   PHYSIOLOGY & BEHAVIOR

Role of GPR81 in lactate-mediated reduction of adipose lipolysis

(2008) Tian-Quan Cai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

(2008) Changlu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elucidation of signaling and functional activities of an orphan GPCR, GPR81

(2008) Hongfei Ge et al.   JOURNAL OF LIPID RESEARCH