Discovery of ethyl urea derivatives as inhibitors of islet amyloid polypeptide fibrillization and cytotoxicity

In Vitro Evaluation of Hypoglycemic Agents to Target Human Islet Amyloid Polypeptide: A Key Protein Involved in Amyloid Deposition and Beta-Cell Loss

(2015) Jessica S. Fortin et al.   Canadian Journal of Diabetes

Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis

(2014) Jean D. Sipe et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Islet amyloid with macrophage migration correlates with augmented β-cell deficits in type 2 diabetic patients

(2014) Kosuke Kamata et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies

(2014) Yaron Bram et al.   Scientific Reports

Mechanisms of islet amyloidosis toxicity in type 2 diabetes

(2013) Andisheh Abedini et al.   FEBS LETTERS

Cosolvent effects on the fibrillation reaction of human IAPP

(2013) Janine Seeliger et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Islet amyloid polypeptide toxicity and membrane interactions

(2013) P. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide

(2012) Biao Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis of the Inhibition and Remodeling of Islet Amyloid Polypeptide Amyloid Fibers by Flavanols

(2012) Ping Cao et al.   BIOCHEMISTRY

Inhibition of Amyloid Formation

(2012) Torleif Härd et al.   JOURNAL OF MOLECULAR BIOLOGY

Resveratrol Inhibits the Formation of Multiple-Layered β-Sheet Oligomers of the Human Islet Amyloid Polypeptide Segment 22–27

(2011) Ping Jiang et al.   BIOPHYSICAL JOURNAL

Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC–MS/MS and their pharmacokinetics in dogs

(2011) Miguel Muzzio et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

The effect of curcumin on human islet amyloid polypeptide misfolding and toxicity

(2010) Marie Daval et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Porcine islet amyloid polypeptide fragments are refractory to amyloid formation

(2010) Xin Zhang et al.   FEBS LETTERS

N-4-iodophenyl-N′-2-chloroethylurea, a novel potential anticancer agent with colon-specific accumulation: radioiodination and comparative in vivo biodistribution profiles

(2009) Emmanuelle Mounetou et al.   INVESTIGATIONAL NEW DRUGS

Rifampicin Does Not Prevent Amyloid Fibril Formation by Human Islet Amyloid Polypeptide but Does Inhibit Fibril Thioflavin-T Interactions: Implications for Mechanistic Studies of β-Cell Death†

(2008) Fanling Meng et al.   BIOCHEMISTRY

Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression

(2008) Jessica S. Fortin et al.   BIOORGANIC & MEDICINAL CHEMISTRY