Modulation of Extracellular Matrix Rigidity Via Riboflavin‐mediated Photocrosslinking Regulates Invasive Motility and Treatment Response in a 3D Pancreatic Tumor Model

Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

(2017) A J Rice et al.   Oncogenesis

ECM Composition and Rheology Regulate Growth, Motility, and Response to Photodynamic Therapy in 3D Models of Pancreatic Ductal Adenocarcinoma

(2016) Gwendolyn M. Cramer et al.   MOLECULAR CANCER RESEARCH

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

(2015) C. J. Whatcott et al.   CLINICAL CANCER RESEARCH

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

(2014) M T Huggett et al.   BRITISH JOURNAL OF CANCER

An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models

(2014) Jonathan P. Celli et al.   Scientific Reports

Impact of treatment response metrics on photodynamic therapy planning and outcomes in a three-dimensional model of ovarian cancer

(2013) Sriram Anbil et al.   JOURNAL OF BIOMEDICAL OPTICS

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

(2013) K. Alessandri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer cell migration within 3D layer-by-layer microfabricated photocrosslinked PEG scaffolds with tunable stiffness

(2012) Pranav Soman et al.   BIOMATERIALS

A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model

(2012) B. J. Gill et al.   CANCER RESEARCH

The Pancreas Cancer Microenvironment

(2012) C. Feig et al.   CLINICAL CANCER RESEARCH

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

(2012) K.-V. Nguyen-Ngoc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Examining the Suitability of Riboflavin/UVA Treatment for Strengthening the Stromal Bioequivalent of a Human Cornea Construct

(2011) Gesa Maria Grobe et al.   CURRENT EYE RESEARCH

Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion

(2011) Mario A. Shields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of riboflavin/UVA corneal cross-linking on keratocytes and collagen fibres in human cornea

(2010) Rita Mencucci et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

Engineering Cartilage in a Photochemically Crosslinked Collagen Gel

(2010) Shinichi Ibusuki et al.   Journal of Knee Surgery

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

Corneal crosslinking: Riboflavin concentration in corneal stroma exposed with and without epithelium

(2009) Stefano Baiocchi et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY