Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems

Qualitative and Quantitative Characterization of Composition Heterogeneity on the Surface of Spray Dried Amorphous Solid Dispersion Particles by an Advanced Surface Analysis Platform with High Surface Sensitivity and Superior Spatial Resolution

(2018) Sonal V. Bhujbal et al.   MOLECULAR PHARMACEUTICS

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria

(2017) Lisa Frueh et al.   ACS Infectious Diseases

Spray drying formulation of amorphous solid dispersions

(2016) Abhishek Singh et al.   ADVANCED DRUG DELIVERY REVIEWS

The role of the carrier in the formulation of pharmaceutical solid dispersions. Part II: amorphous carriers

(2016) Tu Van Duong et al.   Expert Opinion on Drug Delivery

Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs

(2016) Shrawan Baghel et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Preparation and Evaluation of Solid Dispersion of Atorvastatin Calcium with Soluplus® by Spray Drying Technique

(2014) Eun-Sol Ha et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers

(2014) Aaron Nilsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

(2013) A. Nilsen et al.   Science Translational Medicine

Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs

(2012) Kohsaku Kawakami   ADVANCED DRUG DELIVERY REVIEWS

To evaluate the change in release from solid dispersion using sodium lauryl sulfate and model drug sulfathiazole

(2012) Rutesh H. Dave et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

A Win–Win Solution in Oral Delivery of Lipophilic Drugs: Supersaturation via Amorphous Solid Dispersions Increases Apparent Solubility without Sacrifice of Intestinal Membrane Permeability

(2012) Jonathan M. Miller et al.   MOLECULAR PHARMACEUTICS

Supersaturation–Nucleation Behavior of Poorly Soluble Drugs and its Impact on the Oral Absorption of Drugs in Thermodynamically High-Energy Forms

(2011) Shunsuke Ozaki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cocrystals of Quercetin with Improved Solubility and Oral Bioavailability

(2011) Adam J. Smith et al.   MOLECULAR PHARMACEUTICS

The Threat of Artemisinin-Resistant Malaria

(2011) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Optimization of endochin-like quinolones for antimalarial activity

(2010) Rolf Winter et al.   EXPERIMENTAL PARASITOLOGY

Using Cocrystals To Systematically Modulate Aqueous Solubility and Melting Behavior of an Anticancer Drug

(2009) Christer B. Aakeröy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydroxypropyl Methylcellulose Acetate Succinate-Based Spray-Dried Dispersions: An Overview

(2008) Dwayne T. Friesen et al.   MOLECULAR PHARMACEUTICS

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE