Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs

Published 2016 View Full Article

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Title
Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs
Authors
Keywords
solid dispersion, Biopharmaceutics Classification System, crystallization, dissolution, drug-excipient interaction, formulation, in silico modeling, oral drug delivery, polymeric drug delivery systems, supersaturation
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 105, Issue 9, Pages 2527-2544
Publisher
Elsevier BV
Online
2016-01-23
DOI
10.1016/j.xphs.2015.10.008

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