Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1α and fatty acid metabolism in skeletal muscle

PDE/cAMP/Epac/C/EBP-β Signaling Cascade Regulates Mitochondria Biogenesis of Tubular Epithelial Cells in Renal Fibrosis

(2018) Hao Ding et al.   ANTIOXIDANTS & REDOX SIGNALING

Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac

(2016) L Zhou et al.   Translational Psychiatry

Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus

(2015) H. B. Fernandes et al.   JOURNAL OF NEUROSCIENCE

AMP kinase in exercise adaptation of skeletal muscle

(2014) Niels Jessen et al.   DRUG DISCOVERY TODAY

Role of cyclic AMP sensor Epac1 in masseter muscle hypertrophy and myosin heavy chain transition induced by β2-adrenoceptor stimulation

(2014) Yoshiki Ohnuki et al.   JOURNAL OF PHYSIOLOGY-LONDON

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

(2013) Brendan Egan et al.   Cell Metabolism

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome

(2013) Alan K. L. Kai et al.   FASEB JOURNAL

Exercise, GLUT4, and Skeletal Muscle Glucose Uptake

(2013) Erik A. Richter et al.   PHYSIOLOGICAL REVIEWS

Cyclic AMP sensor EPAC proteins and energy homeostasis

(2013) Muayad Almahariq et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

AMPK and Exercise: Glucose Uptake and Insulin Sensitivity

(2013) Hayley M. O'Neill   Diabetes & Metabolism Journal

cAMP signaling in skeletal muscle adaptation: hypertrophy, metabolism, and regeneration

(2012) Rebecca Berdeaux et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

Activation of Protein Kinase A and Exchange Protein Directly Activated by cAMP Promotes Adipocyte Differentiation of Human Mesenchymal Stem Cells

(2012) Bingbing Jia et al.   PLoS One

Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation

(2012) S. M. Haldar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human giant congenital melanocytic nevus exhibits potential proteomic alterations leading to melanotumorigenesis

(2012) Hyoung Kyu Kim et al.   Proteome Science

Lack of β2-AR improves exercise capacity and skeletal muscle oxidative phenotype in mice

(2012) V. A. Voltarelli et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Fucosylated glycoproteomic approach to identify a complement component 9 associated with squamous cell lung cancer (SQLC)

(2011) Arul Narayanasamy et al.   Journal of Proteomics

The Effect of Exercise and Nutrition on Intramuscular Fat Metabolism and Insulin Sensitivity

(2010) Christopher S. Shaw et al.   Annual Review of Nutrition

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

Gsα deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency

(2009) Min Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Involvement of cAMP/Epac/PI3K-dependent pathway in the antiproteolytic effect of epinephrine on rat skeletal muscle

(2009) Amanda Martins Baviera et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy

(2008) Mélanie Métrich et al.   CIRCULATION RESEARCH

Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation

(2008) Norbert Frey et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic Profiling of Endothelial Cells in Human Lung Cancer

(2008) Hye-Jeong Park et al.   JOURNAL OF PROTEOME RESEARCH

Cyclic nucleotide analogs as probes of signaling pathways

(2008) Heiko Poppe et al.   NATURE METHODS

Role of β-Adrenoceptor Signaling in Skeletal Muscle: Implications for Muscle Wasting and Disease

(2008) Gordon S. Lynch et al.   PHYSIOLOGICAL REVIEWS