Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries
Authors
Keywords
-
Journal
Oxidative Medicine and Cellular Longevity
Volume 2020, Issue -, Pages 1-17
Publisher
Hindawi Limited
Online
2020-01-29
DOI
10.1155/2020/5967434
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Farrerol Ameliorates TNBS-Induced Colonic Inflammation by Inhibiting ERK1/2, JNK1/2, and NF-κB Signaling Pathway
- (2018) Xin Ran et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Crystal structure of GSK3β in complex with the flavonoid, morin
- (2018) Kuglae Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line
- (2018) Bei Cui et al. BIOMEDICINE & PHARMACOTHERAPY
- Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway
- (2017) Jialin Duan et al. Scientific Reports
- Sustained ERK activation-mediated proliferation inhibition of farrerol on human gastric carcinoma cell line by G0/G1-phase cell-cycle arrest
- (2016) Enli Liu et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Nrf2-mediated liver protection by esculentoside A against acetaminophen toxicity through the AMPK/Akt/GSK3β pathway
- (2016) Lidong Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Apigenin and naringenin ameliorate PKCβII-associated endothelial dysfunction via regulating ROS/caspase-3 and NO pathway in endothelial cells exposed to high glucose
- (2016) Weiwei Qin et al. VASCULAR PHARMACOLOGY
- Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3
- (2015) John D. Hayes et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The antioxidative potential of farrerol occurs via the activation of Nrf2 mediated HO-1 signaling in RAW 264.7 cells
- (2015) Xinxin Ci et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Global and Regional Patterns in Cardiovascular Mortality From 1990 to 2013
- (2015) Gregory A. Roth et al. CIRCULATION
- Farrerol can attenuate the aortic lesion in spontaneously hypertensive rats via the upregulation of eNOS and reduction of NAD(P)H oxidase activity
- (2015) Xiaojiang Qin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression
- (2015) Seung Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3)
- (2015) Meenakshi B. Kannan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation
- (2015) Hai-Yan Xing et al. PLoS One
- Farrerol regulates occludin expression in hydrogen peroxide-induced EA.hy926 cells by modulating ERK1/2 activity
- (2014) Jiankuan Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations
- (2014) Rashmi Kumari et al. Journal of Chemical Information and Modeling
- Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through PI3K/Akt/GSK-3β signaling events in PC12 cells exposed to lead
- (2014) Chengchong Li et al. NEUROTOXICOLOGY AND TERATOLOGY
- Protective effects of farrerol against hydrogen-peroxide-induced apoptosis in human endothelium-derived EA.hy926 cells
- (2013) Jian-Kuan Li et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Farrerol regulates antimicrobial peptide expression and reduces Staphylococcus aureus internalization into bovine mammary epithelial cells
- (2013) Zhengtao Yang et al. MICROBIAL PATHOGENESIS
- Citrus Flavanones: What Is Their Role in Cardiovascular Protection?
- (2012) Audrey Chanet et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- In silico prediction of inhibitory effects of pyrazol-5-one and indazole derivatives on GSK3β kinase enzyme
- (2012) Fangfang Wang et al. JOURNAL OF MOLECULAR STRUCTURE
- Dietary Flavonoids and Risk of Stroke in Women
- (2012) Aedín Cassidy et al. STROKE
- Involvement of estrogen receptor-β in farrerol inhibition of rat thoracic aorta vascular smooth muscle cell proliferation
- (2011) Qun-yi Li et al. ACTA PHARMACOLOGICA SINICA
- Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3
- (2011) Ana I. Rojo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Citrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome
- (2011) Stefano Rizza et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity
- (2010) Přemysl Mladěnka et al. FREE RADICAL BIOLOGY AND MEDICINE
- Improved side-chain torsion potentials for the Amber ff99SB protein force field
- (2010) Kresten Lindorff-Larsen et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Endothelial Function and Oxidative Stress in Cardiovascular Diseases
- (2009) Yukihito Higashi et al. CIRCULATION JOURNAL
- Nrf2:INrf2 (Keap1) signaling in oxidative stress
- (2009) James W. Kaspar et al. FREE RADICAL BIOLOGY AND MEDICINE
- AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
- (2009) Garrett M. Morris et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Molecular mechanisms of Nrf2-mediated antioxidant response
- (2008) Wenge Li et al. MOLECULAR CARCINOGENESIS
- Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3 Inactivation
- (2008) T. M. Thornton et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now