The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling
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Title
The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2020, Issue -, Pages 1-14
Publisher
Hindawi Limited
Online
2020-01-09
DOI
10.1155/2020/5167292
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- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
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