Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Clonal Evolution in Cancer: A Tale of Twisted Twines

(2015) Michalina Janiszewska et al.   Cell Stem Cell

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

(2015) R. S. Goswami et al.   CLINICAL CANCER RESEARCH

Clonal Evolution Enhances Leukemia-Propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia through Akt/mTORC1 Pathway Activation

(2014) Jessica S. Blackburn et al.   CANCER CELL

Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

(2014) David G. McFadden et al.   CELL

Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance

(2014) Hariharan Easwaran et al.   MOLECULAR CELL

Tumour heterogeneity and the evolution of polyclonal drug resistance

(2014) Rebecca A. Burrell et al.   Molecular Oncology

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

(2014) Andriy Marusyk et al.   NATURE

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

Tumor Heterogeneity Confounds and Illuminates: A case for Darwinian tumor evolution

(2014) Kornelia Polyak   NATURE MEDICINE

Optimized cell transplantation using adult rag2 mutant zebrafish

(2014) Qin Tang et al.   NATURE METHODS

Heterogeneous Tumor Subpopulations Cooperate to Drive Invasion

(2014) Anna Chapman et al.   Cell Reports

Inference of Tumor Evolution during Chemotherapy by Computational Modeling and In Situ Analysis of Genetic and Phenotypic Cellular Diversity

(2014) Vanessa Almendro et al.   Cell Reports

Zebrafish embryo as a tool to study tumor/endothelial cell cross-talk

(2013) Chiara Tobia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

(2013) Dan A. Landau et al.   CELL

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

(2013) A. Sottoriva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy

(2013) H. Shi et al.   Cancer Discovery

Darwinian evolution and tiding clones in multiple myeloma

(2012) N. J. Bahlis   BLOOD

Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis

(2012) Shizhen Zhu et al.   CANCER CELL

In Vivo Imaging of Tumor-Propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma

(2012) Myron S. Ignatius et al.   CANCER CELL

Imaging interactions between macrophages and tumour cells that are involved in metastasisin vivoandin vitro

(2012) A. DOVAS et al.   JOURNAL OF MICROSCOPY

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

(2012) A. G. Schepers et al.   SCIENCE

Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis

(2012) L. Ritsma et al.   Science Translational Medicine

Brief Report: Intravital Imaging of Cancer Stem Cell Plasticity in Mammary Tumors

(2012) Anoek Zomer et al.   STEM CELLS

Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia

(2011) M. J. Clemente et al.   BLOOD

Intravital Imaging

(2011) Mikael J. Pittet et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

A Novel Xenograft Model in Zebrafish for High-Resolution Investigating Dynamics of Neovascularization in Tumors

(2011) Chengjian Zhao et al.   PLoS One

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia

(2010) A. C. H. Smith et al.   BLOOD

T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation

(2010) Hui Feng et al.   CANCER CELL

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

Visualizing extravasation dynamics of metastatic tumor cells

(2010) K. Stoletov et al.   JOURNAL OF CELL SCIENCE

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

(2010) Jeffry D Sander et al.   NATURE METHODS

Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

(2010) C. Lopez-Garcia et al.   SCIENCE

Targeting the osteosarcoma cancer stem cell

(2010) Valerie A Siclari et al.   Journal of Orthopaedic Surgery and Research

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Intravital imaging of metastatic behavior through a mammary imaging window

(2008) Dmitriy Kedrin et al.   NATURE METHODS

Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish

(2008) D M Langenau et al.   ONCOGENE

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE