Curculigoside Protects against Excess-Iron-Induced Bone Loss by Attenuating Akt-FoxO1-Dependent Oxidative Damage to Mice and Osteoblastic MC3T3-E1 Cells

FoxO1 expression in osteoblasts modulates bone formation through resistance to oxidative stress in mice

(2018) Yixin Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bone abnormalities in young male rats with iron intervention and possible mechanisms

(2018) Yanqin Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Monotropein attenuates ovariectomy and LPS-induced bone loss in mice and decreases inflammatory impairment on osteoblast through blocking activation of NF-κB pathway

(2018) Yu-Qiong He et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Iron overload induces G1 phase arrest and autophagy in murine preosteoblast cells

(2018) Wan-Jing Cen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Postmenopausal Iron Overload Exacerbated Bone Loss by Promoting the Degradation of Type I Collagen

(2017) Qian Cheng et al.   Biomed Research International

The New Synthetic H2S-Releasing SDSS Protects MC3T3-E1 Osteoblasts against H2O2-Induced Apoptosis by Suppressing Oxidative Stress, Inhibiting MAPKs, and Activating the PI3K/Akt Pathway

(2017) Xiaofei Yan et al.   Frontiers in Pharmacology

Clinical Impact and Cellular Mechanisms of Iron Overload-Associated Bone Loss

(2017) Viktória Jeney   Frontiers in Pharmacology

Bioprospecting the Curculigoside-Cinnamic Acid-Rich Fraction from Molineria latifolia Rhizome as a Potential Antioxidant Therapeutic Agent

(2016) Der Ooi et al.   MOLECULES

SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

(2016) Xiaolong Gu et al.   Oncotarget

Iron overload induced death of osteoblasts in vitro: involvement of the mitochondrial apoptotic pathway

(2016) Qing Tian et al.   PeerJ

Effects of Curculigoside on Memory Impairment and Bone Loss via Anti-Oxidative Character in APP/PS1 Mutated Transgenic Mice

(2015) Lu Zhao et al.   PLoS One

Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels

(2014) F. Rossi et al.   HAEMATOLOGICA

Thalassemia Bone Disease: A 19-Year Longitudinal Analysis

(2014) Phillip Wong et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bcl2 Deficiency Activates FoxO through Akt Inactivation and Accelerates Osteoblast Differentiation

(2014) Takeshi Moriishi et al.   PLoS One

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

(2014) Shoshana M. Bartell et al.   Nature Communications

Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cellsin vitroand suppresses hematopoiesis in iron overload patients

(2013) Wenyi Lu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Curculigoside isolated from Curculigo orchioides prevents hydrogen peroxide-induced dysfunction and oxidative damage in calvarial osteoblasts

(2012) Y. Wang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

Neuroprotective effects of curculigoside against NMDA-induced neuronal excitoxicity in vitro

(2012) Zhen Tian et al.   FOOD AND CHEMICAL TOXICOLOGY

Loss of Nrf2 accelerates ionizing radiation-induced bone loss by upregulating RANKL

(2012) Tapasi Rana et al.   FREE RADICAL BIOLOGY AND MEDICINE

Iron overload accelerates bone loss in healthy postmenopausal women and middle-aged men: A 3-year retrospective longitudinal study

(2012) Beom-Jun Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Ameliorative Effects of Curculigoside from Curculigo orchioides Gaertn on Learning and Memory in Aged Rats

(2012) Xiu-Ying Wu et al.   MOLECULES

Up-regulation of VEGF by MC3T3-E1 Cells Treated with Curculigoside

(2011) Chengjian Ma et al.   PHYTOTHERAPY RESEARCH

Bone loss caused by iron overload in a murine model: importance of oxidative stress

(2010) J. Tsay et al.   BLOOD

FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

(2010) Marie-Therese Rached et al.   Cell Metabolism

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS