MUC1 oncoprotein mitigates ER stress via CDA-mediated reprogramming of pyrimidine metabolism

Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation

(2019) Albert Castellví et al.   Scientific Reports

MUC1-C INTEGRATES CHROMATIN REMODELING AND PARP1 ACTIVITY IN THE DNA DAMAGE RESPONSE OF TRIPLE-NEGATIVE BREAST CANCER CELLS

(2019) Masaaki Yamamoto et al.   CANCER RESEARCH

Crosstalk between Calcium and ROS in Pathophysiological Conditions

(2019) Simona Feno et al.   Oxidative Medicine and Cellular Longevity

The unfolded protein response as a target for anticancer therapeutics

(2018) Mengxiong Wang et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

(2018) Minkyung Song et al.   NATURE

ROS and the DNA damage response in cancer

(2018) Upadhyayula Sai Srinivas et al.   Redox Biology

Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells

(2017) Teklab Gebregiworgis et al.   JOURNAL OF PROTEOME RESEARCH

The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53

(2017) Daniel Menendez et al.   MOLECULAR CANCER RESEARCH

Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells

(2017) Zhen Ren et al.   TOXICOLOGY

C-to-U editing and site-directed RNA editing for the correction of genetic mutations

(2017) Luyen Thi Vu et al.   BioScience Trends

MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer

(2017) Gennifer Goode et al.   PLoS One

Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs)

(2017) Li Wang et al.   PLoS One

MUC1-C activates EZH2 expression and function in human cancer cells

(2017) Hasan Rajabi et al.   Scientific Reports

Endoplasmic Reticulum Stress and Associated ROS

(2016) Hafiz Zeeshan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation

(2016) Simon Gemble et al.   JOURNAL OF CELL SCIENCE

DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells

(2016) H Rajabi et al.   ONCOGENE

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

(2016) L Dumartin et al.   ONCOGENE

MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia

(2016) Ashujit Tagde et al.   Oncotarget

MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors

(2016) Masayuki Hiraki et al.   Scientific Reports

Discovery of a novel glucose metabolism in cancer: The role of endoplasmic reticulum beyond glycolysis and pentose phosphate shunt

(2016) Cecilia Marini et al.   Scientific Reports

IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to CXC195-induced apoptosis in human bladder carcinoma T24 cells

(2015) Tao Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer

(2015) F.-G. Ye et al.   CANCER RESEARCH

Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress

(2015) Ammad Ahmad Farooqi et al.   TUMOR BIOLOGY

Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure

(2015) Emilyn U. Alejandro et al.   Cell Reports

Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life

(2014) Martin S. Denzel et al.   CELL

Role of cytidine deaminase in toxicity and efficacy of nucleosidic analogs

(2014) Cindy Serdjebi et al.   Expert Opinion on Drug Metabolism & Toxicology

Redox controls UPR to control redox

(2014) D. Eletto et al.   JOURNAL OF CELL SCIENCE

Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets

(2014) N. Kannan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

ER stress suppresses DNA double-strand break repair and sensitizes tumor cells to ionizing radiation by stimulating proteasomal degradation of Rad51

(2013) Tohru Yamamori et al.   FEBS LETTERS

Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase

(2013) N Weizman et al.   ONCOGENE

MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes

(2013) S Nath et al.   Oncogenesis

Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice

(2012) C. L. Kriss et al.   BLOOD

ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

(2012) José Manuel Rodríguez-Vargas et al.   CELL RESEARCH

AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia

(2012) A M Norris et al.   ONCOGENE

Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development

(2012) E Chevet et al.   ONCOGENE

MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer

(2012) N. V. Chaika et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome

(2011) Pauline Chabosseau et al.   Nature Communications

Lack of glucose recycling between endoplasmic reticulum and cytoplasm underlies cellular dysfunction in glucose-6-phosphatase- -deficient neutrophils in a congenital neutropenia syndrome

(2010) H. S. Jun et al.   BLOOD

The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF

(2010) M E Behrens et al.   ONCOGENE

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

(2010) Y. Hayakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

(2009) Gang Li et al.   JOURNAL OF CELL BIOLOGY

JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma

(2009) Qingshan Chang et al.   Molecular Cancer

MUC1 Oncoprotein Blocks Death Receptor-Mediated Apoptosis by Inhibiting Recruitment of Caspase-8

(2008) N. Agata et al.   CANCER RESEARCH

MUC1 mucin interacts with calcium-modulating cyclophilin ligand

(2008) Wei Guang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phosphorylation of MUC1 by Met Modulates Interaction with p53 and MMP1 Expression

(2008) Pankaj K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

(2008) Lijian Hui et al.   JOURNAL OF CLINICAL INVESTIGATION

Membrane phospholipid synthesis and endoplasmic reticulum function

(2008) Paolo Fagone et al.   JOURNAL OF LIPID RESEARCH

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins

(2008) J. Hauser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA