MYOCD and SMAD3/SMAD4 form a positive feedback loop and drive TGF-β-induced epithelial–mesenchymal transition in non-small cell lung cancer

Cancer statistics, 2019

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Tumor Progression Is Mediated by Thymosin-β4 through a TGFβ/MRTF Signaling Axis

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Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γ in non-small cell lung cancer

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Overexpression of GRB2 Enhances Epithelial to Mesenchymal Transition of A549 Cells by Upregulating SNAIL Expression

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Downregulation of the TGFβ Pseudoreceptor BAMBI in Non–Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion

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Emerging roles of the myocardin family of proteins in lipid and glucose metabolism

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Myocardin Regulates Vascular Smooth Muscle Cell Inflammatory Activation and DiseaseSignificance

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Matrix Rigidity Mediates TGFβ1-induced Epithelial-Myofibroblast Transition by Controlling Cytoskeletal Organization and MRTF-A Localization

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TGF-β-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer

(2015) Haiping Yang et al.   LUNG CANCER

Repression of TIF1γ by SOX2 promotes TGF-β-induced epithelial–mesenchymal transition in non-small-cell lung cancer

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Structural determinants of Smad function in TGF-β signaling

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The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells

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Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β–dependent cancer metastasis

(2014) Jianfei Xue et al.   JOURNAL OF CLINICAL INVESTIGATION

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

TGF- -inducible microRNA-183 silences tumor-associated natural killer cells

(2014) S. S. Donatelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Smad3-mediated Myocardin Silencing

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Induction of MicroRNA-1 by Myocardin in Smooth Muscle Cells Inhibits Cell Proliferation

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Myocardin Functions as an Effective Inducer of Growth Arrest and Differentiation in Human Uterine Leiomyosarcoma Cells

(2010) Y. Kimura et al.   CANCER RESEARCH

Transforming Growth Factor-β and Notch Signaling Mediate Stem Cell Differentiation into Smooth Muscle Cells

(2010) Kyle Kurpinski et al.   STEM CELLS

ConceptGen: a gene set enrichment and gene set relation mapping tool

(2009) Maureen A. Sartor et al.   BIOINFORMATICS

Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas

(2009) G. Perot et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

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The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

TGFβ in Cancer

(2008) Joan Massagué   CELL

Ski and SnoN, potent negative regulators of TGF-β signaling

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The Human Protein Atlas-a tool for pathology

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A positive role for Myc in TGFβ-induced Snail transcription and epithelial-to-mesenchymal transition

(2008) A P Smith et al.   ONCOGENE

Introduction

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p53 Plays a Role in Mesenchymal Differentiation Programs, in a Cell Fate Dependent Manner

(2008) Alina Molchadsky et al.   PLoS One