LncRNAGAS5 sponges miRNA-221 to promote neurons apoptosis by up-regulated PUMA under hypoxia condition

LncRNA GAS5 regulates ischemic stroke as a competing endogenous RNA for miR-137 to regulate the Notch1 signaling pathway

(2018) Fenghui Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells

(2018) Qian Wu et al.   BIOCHEMICAL PHARMACOLOGY

Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p

(2018) Shuqin Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Extracellular vesicle-mimetic nanovesicles transport LncRNA-H19 as competing endogenous RNA for the treatment of diabetic wounds

(2018) Shi-Cong Tao et al.   DRUG DELIVERY

Hepatocyte nuclear receptor SHP suppresses inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis

(2018) An Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Existing and novel biomarkers for precision medicine in systemic sclerosis

(2018) Peter J. Wermuth et al.   Nature Reviews Rheumatology

Netrin-1 Promotes Synaptic Formation and Axonal Regeneration via JNK1/c-Jun Pathway after the Middle Cerebral Artery Occlusion

(2018) Mouwei Zheng et al.   Frontiers in Cellular Neuroscience

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility

(2018) Quynh-Nhu Nguyen et al.   Cell Death & Disease

The long noncoding RNA GAS5 negatively regulates the adipogenic differentiation of MSCs by modulating the miR-18a/CTGF axis as a ceRNA

(2018) Ming Li et al.   Cell Death & Disease

A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry

(2018) Julie C. Ullman et al.   Nature Communications

Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells

(2018) Yoav Lubelsky et al.   NATURE

Elucidating sex differences in response to cerebral ischemia: immunoregulatory mechanisms and the role of microRNAs

(2018) Georgia Kaidonis et al.   PROGRESS IN NEUROBIOLOGY

Neighborhood socioeconomic status at the age of 40 years and ischemic stroke before the age of 50 years: A nationwide cohort study from Sweden

(2017) Axel C Carlsson et al.   International Journal of Stroke

Long Noncoding RNA GAS5 Suppresses Cell Growth and Epithelial-Mesenchymal Transition in Osteosarcoma by Regulating the miR-221/ARHI Pathway

(2017) Kaishan Ye et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Targeting noncoding RNAs in disease

(2017) Brian D. Adams et al.   JOURNAL OF CLINICAL INVESTIGATION

Annexin A2 contributes to cisplatin resistance by activation of JNK-p53 pathway in non-small cell lung cancer cells

(2017) Xiaomin Feng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

(2017) Hui Wang et al.   Molecular Cancer

14,15-EET Suppresses Neuronal Apoptosis in Ischemia–Reperfusion Through the Mitochondrial Pathway

(2017) Hui-Xia Geng et al.   NEUROCHEMICAL RESEARCH

A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease

(2017) Jaishree Jalewa et al.   NEUROPHARMACOLOGY

Overview of long non-coding RNA and mRNA expression in response to methamphetamine treatment in vitro

(2017) Kun Xiong et al.   TOXICOLOGY IN VITRO

The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells

(2017) Jun Yang et al.   Oncotarget

Melatonin Promotes Brain-Derived Neurotrophic Factor (BDNF) Expression and Anti-Apoptotic Effects in Neonatal Hemolytic Hyperbilirubinemia via a Phospholipase (PLC)-Mediated Mechanism

(2017) Yong Luo et al.   MEDICAL SCIENCE MONITOR

Galanin Protects from Caspase-8/12-initiated Neuronal Apoptosis in the Ischemic Mouse Brain via GalR1

(2017) Yun Li et al.   Aging and Disease

Mesenchymal stem cells protect neurons against hypoxic-ischemic injury via inhibiting parthanatos, necroptosis, and apoptosis, but not autophagy

(2016) Deyan Kong et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

MicroRNA-493 regulates angiogenesis in a rat model of ischemic stroke by targeting MIF

(2016) Qian Li et al.   FEBS Journal

Downregulation of the Long Non-Coding RNA Meg3 Promotes Angiogenesis After Ischemic Brain Injury by Activating Notch Signaling

(2016) Juan Liu et al.   MOLECULAR NEUROBIOLOGY

L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response

(2016) Lina Zhang et al.   NEUROCHEMICAL RESEARCH

Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma

(2015) J.-J. Zhao et al.   CANCER RESEARCH

Long Non-coding RNA Growth Arrest-specific Transcript 5 (GAS5) Inhibits Liver Fibrogenesis through a Mechanism of Competing Endogenous RNA

(2015) Fujun Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long Noncoding RNA FosDT Promotes Ischemic Brain Injury by Interacting with REST-Associated Chromatin-Modifying Proteins

(2015) S. L. Mehta et al.   JOURNAL OF NEUROSCIENCE

PUMA is invovled in ischemia/reperfusion-induced apoptosis of mouse cerebral astrocytes

(2015) H. Chen et al.   NEUROSCIENCE

lncRNA GAS5 enhances G1 cell cycle arrest via binding to YBX1 to regulate p21 expression in stomach cancer

(2015) Yongchao Liu et al.   Scientific Reports

Long noncoding RNA GAS5 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

(2014) Dandan Yin et al.   MEDICAL ONCOLOGY

Negative regulation of lncRNA GAS5 by miR-21

(2013) Z Zhang et al.   CELL DEATH AND DIFFERENTIATION

MicroRNAs as novel biological targets for detection and regulation

(2013) Jinbo Li et al.   CHEMICAL SOCIETY REVIEWS

Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-κB pathways

(2010) Xin Liu et al.   BIOMATERIALS