FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

Activation of the Endonuclease that Defines mRNA 3′ Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex

(2019) Chris H. Hill et al.   MOLECULAR CELL

A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2

(2019) Emilie L Dubois et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage

(2019) David Lopez-Martinez et al.   Cell Reports

An integrated workflow for crosslinking mass spectrometry

(2019) Marta L Mendes et al.   Molecular Systems Biology

Structure of the Fanconi anaemia monoubiquitin ligase complex

(2019) Shabih Shakeel et al.   NATURE

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

(2018) Takanori Nakane et al.   eLife

In-Search Assignment of Monoisotopic Peaks Improves the Identification of Cross-Linked Peptides

(2018) Swantje Lenz et al.   JOURNAL OF PROTEOME RESEARCH

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination

(2017) Winnie Tan et al.   EXPERIMENTAL HEMATOLOGY

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

(2017) Sylvie van Twest et al.   MOLECULAR CELL

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response

(2017) Elizabeth L. Thompson et al.   NUCLEIC ACIDS RESEARCH

Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

(2017) Katerina Naydenova et al.   Nature Communications

Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex

(2017) Ronald S. Cheung et al.   Cell Reports

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2

(2017) Paolo Swuec et al.   Cell Reports

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes

(2016) Florian Weissmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2

(2016) Chih-Chao Liang et al.   Nature Communications

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

The Fanconi Anemia DNA Repair Pathway: Structural and Functional Insights into a Complex Disorder

(2014) Helen Walden et al.   Annual Review of Biophysics

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

(2014) Eeson Rajendra et al.   MOLECULAR CELL

XPF-ERCC1 Acts in Unhooking DNA Interstrand Crosslinks in Cooperation with FANCD2 and FANCP/SLX4

(2014) Daisy Klein Douwel et al.   MOLECULAR CELL

Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair

(2014) Michael R.G. Hodskinson et al.   MOLECULAR CELL

Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

(2014) Simonne Longerich et al.   NUCLEIC ACIDS RESEARCH

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

(2013) Molly C. Kottemann et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI

(2012) K. Sato et al.   NUCLEIC ACIDS RESEARCH

The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA

(2011) Gerry P Crossan et al.   JOURNAL OF PATHOLOGY

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway

(2011) K. N. Yamamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

(2011) Woo Joo et al.   SCIENCE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2

(2010) Craig MacKay et al.   CELL

Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents

(2010) Katja Kratz et al.   CELL

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

(2010) T. Liu et al.   SCIENCE

Hematopoietic Stem Cell Defects in Mice with Deficiency of Fancd2 or Usp1

(2010) Kalindi Parmar et al.   STEM CELLS

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

(2009) P. Knipscheer et al.   SCIENCE

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

(2008) Markus Räschle et al.   CELL

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

(2008) Masamichi Ishiai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY