TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Biological Functions of Autophagy Genes: A Disease Perspective

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Exercise-Induced Mitophagy in Skeletal Muscle and Heart

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Release from UNC93B1 reinforces the compartmentalized activation of select TLRs

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AMPK in skeletal muscle function and metabolism

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CpG oligodeoxynucleotide preconditioning improves cardiac function after myocardial infarction via modulation of energy metabolism and angiogenesis

(2017) Deng-Cheng Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

(2017) Michalis Agathocleous et al.   NATURE

Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation

(2016) Shigemiki Omiya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL

(2016) Maria Giovanna De Leo et al.   NATURE CELL BIOLOGY

PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain

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Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes

(2015) K. Rostislavleva et al.   SCIENCE

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

(2015) Yongjie Wei et al.   eLife

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

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Effects of Pharmacological AMP Deaminase Inhibition and Ampd1 Deletion on Nucleotide Levels and AMPK Activation in Contracting Skeletal Muscle

(2014) Catheline Plaideau et al.   CHEMISTRY & BIOLOGY

Microbial Sensing by Toll-Like Receptors and Intracellular Nucleic Acid Sensors

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Myomaker is a membrane activator of myoblast fusion and muscle formation

(2013) Douglas P. Millay et al.   NATURE

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons

(2013) Y. Shintani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UNC93B1 mediates differential trafficking of endosomal TLRs

(2013) Bettina L Lee et al.   eLife

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Phosphorylation of LKB1 at Serine 428 by Protein Kinase C-ζ Is Required for Metformin-Enhanced Activation of the AMP-Activated Protein Kinase in Endothelial Cells

(2008) Zhonglin Xie et al.   CIRCULATION

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE