Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis

Regulation of hepatic mitochondrial oxidation by glucose-alanine cycling during starvation in humans

(2019) Kitt Falk Petersen et al.   JOURNAL OF CLINICAL INVESTIGATION

Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

(2018) Rachel J. Perry et al.   CELL

Mechanism for leptin’s acute insulin-independent effect to reverse diabetic ketoacidosis

(2017) Rachel J. Perry et al.   JOURNAL OF CLINICAL INVESTIGATION

The New Biology and Pharmacology of Glucagon

(2017) T. D. Müller et al.   PHYSIOLOGICAL REVIEWS

Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice

(2017) Haruka Okamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)

(2017) Rachel J. Perry et al.   Nature Communications

Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates

(2016) S. J. Henderson et al.   DIABETES OBESITY & METABOLISM

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

(2016) Rachel J. Perry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

(2015) Rachel J. Perry et al.   CELL

Evaluation of Efficacy and Safety of the Glucagon Receptor Antagonist LY2409021 in Patients With Type 2 Diabetes: 12- and 24-Week Phase 2 Studies

(2015) Christof M. Kazda et al.   DIABETES CARE

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content

(2014) João Paulo G. Camporez et al.   JOURNAL OF LIPID RESEARCH

Activation of Calcium/Calmodulin-Dependent Protein Kinase II in Obesity Mediates Suppression of Hepatic Insulin Signaling

(2013) Lale Ozcan et al.   Cell Metabolism

Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice

(2013) João Paulo G. Camporez et al.   ENDOCRINOLOGY

Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity

(2012) Lale Ozcan et al.   Cell Metabolism

Identification and Functional Characterization of Protein Kinase A Phosphorylation Sites in the Major Lipolytic Protein, Adipose Triglyceride Lipase

(2012) Joanne Pagnon et al.   ENDOCRINOLOGY

Malonyl-CoA: the regulator of fatty acid synthesis and oxidation

(2012) Daniel W. Foster   JOURNAL OF CLINICAL INVESTIGATION

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes

(2012) Yiguo Wang et al.   NATURE

SGLT2 Deletion Improves Glucose Homeostasis and Preserves Pancreatic β-Cell Function

(2011) Michael J. Jurczak et al.   DIABETES