Identification of signalling cascades involved in red blood cell shrinkage and vesiculation

Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival

(2014) Neli S. Slavova-Azmanova et al.   BIOCHEMICAL JOURNAL

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD

(2014) A. O. Awojoodu et al.   BLOOD

Label-free proteomic analysis of red blood cell membrane fractions from abdominal aortic aneurysm patients

(2014) Roxana Martinez-Pinna et al.   Proteomics Clinical Applications

Mechanism of faster NO scavenging by older stored red blood cells

(2014) Chen Liu et al.   Redox Biology

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro

(2013) A. Danesh et al.   BLOOD

Nitric oxide scavenging by red cell microparticles

(2013) Chen Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Calcium in Red Blood Cells—A Perilous Balance

(2013) Anna Bogdanova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CR1-mediated ATP Release by Human Red Blood Cells Promotes CR1 Clustering and Modulates the Immune Transfer Process

(2013) Mark I. Melhorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent Phospholipid Scramblase Activity of TMEM16 Protein Family Members

(2013) Jun Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

(2013) Mattia Malvezzi et al.   Nature Communications

Fluoxetine Induced Suicidal Erythrocyte Death

(2013) Kashif Jilani et al.   Toxins

Survival of red blood cells after transfusion: processes and consequences

(2013) Giel J. C. G. M. Bosman   Frontiers in Physiology

AMP-activated protein kinase: new regulation, new roles?

(2012) David Carling et al.   BIOCHEMICAL JOURNAL

Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology

(2012) Adam Wieschhaus et al.   BIOCHEMICAL JOURNAL

Potassium leakage primes stored erythrocytes for phosphatidylserine exposure and shedding of pro-coagulant vesicles

(2012) Patrick Burger et al.   BRITISH JOURNAL OF HAEMATOLOGY

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Enhanced Erythrocyte Membrane Exposure of Phosphatidylserine Following Sorafenib Treatment: Anin vivoandin vitroStudy

(2012) Adrian Lupescu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease

(2012) Lucia De Franceschi et al.   FASEB JOURNAL

Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa

(2012) P. E. J. VAN DER MEIJDEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Moderate Exercise Promotes Human RBC-NOS Activity, NO Production and Deformability through Akt Kinase Pathway

(2012) Frank Suhr et al.   PLoS One

Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’

(2012) Guy C. Brown et al.   TRENDS IN BIOCHEMICAL SCIENCES

Toward a Multiscale Description of Microvascular Flow Regulation: O2-Dependent Release of ATP from Human Erythrocytes and the Distribution of ATP in Capillary Networks

(2012) Daniel Goldman et al.   Frontiers in Physiology

Small-Conductance Ca2+-Activated K+ Channels: Form and Function

(2011) John P. Adelman et al.   Annual Review of Physiology

Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity

(2011) L. De Franceschi et al.   BLOOD

p38 MAPK Activation and Function following Osmotic Shock of Erythrocytes

(2011) Sergios Gatidis et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nitric Oxide Scavenging by Red Blood Cell Microparticles and Cell-Free Hemoglobin as a Mechanism for the Red Cell Storage Lesion

(2011) Chenell Donadee et al.   CIRCULATION

Sorafenib for the management of advanced renal cell carcinoma

(2011) Bernard Escudier   Expert Review of Anticancer Therapy

Doxorubicin and Sorafenib for Treatment of Advanced Hepatocellular Cancer

(2011) Ghassan K. Abou-Alfa et al.   GASTROENTEROLOGY

Storage lesion: role of red blood cell breakdown

(2011) Daniel B. Kim-Shapiro et al.   TRANSFUSION

Microparticles in stored red blood cells as potential mediators of transfusion complications

(2011) Wenche Jy et al.   TRANSFUSION

Ligation of complement receptor 1 increases erythrocyte membrane deformability

(2010) A. M. Glodek et al.   BLOOD

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

(2010) A. Siddiqui-Jain et al.   CANCER RESEARCH

Phospholipid scramblase: An update

(2010) Edouard M. Bevers et al.   FEBS LETTERS

Stimulation of human and mouse erythrocyte Na+-K+-2Cl−cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation

(2010) Brice Sid et al.   JOURNAL OF PHYSIOLOGY-LONDON

Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

(2010) F. Baffert et al.   MOLECULAR CANCER THERAPEUTICS

AT7867 Is a Potent and Oral Inhibitor of AKT and p70 S6 Kinase That Induces Pharmacodynamic Changes and Inhibits Human Tumor Xenograft Growth

(2010) K. M. Grimshaw et al.   MOLECULAR CANCER THERAPEUTICS

Basal Release of ATP: An Autocrine-Paracrine Mechanism for Cell Regulation

(2010) R. Corriden et al.   Science Signaling

Sorafenib: Rays of Hope in Thyroid Cancer

(2010) Leonidas H. Duntas et al.   THYROID

An improved red blood cell additive solution maintains 2,3-diphosphoglycerate and adenosine triphosphate levels by an enhancing effect on phosphofructokinase activity during cold storage

(2010) Patrick Burger et al.   TRANSFUSION

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

(2009) Thomas O'Hare et al.   CANCER CELL

Effects of p38 MAP Kinase Inhibitors on the Differentiation and Maturation of Erythroid Progenitors

(2009) Deidre A. Dalmas et al.   TOXICOLOGIC PATHOLOGY

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

Discovery of a potent and selective Aurora kinase inhibitor

(2008) Johan D. Oslob et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Erythrocyte vesiculation: a self-protective mechanism?

(2008) Frans L. A. Willekens et al.   BRITISH JOURNAL OF HAEMATOLOGY

Regulation of erythrocyte survival by AMP-activated protein kinase

(2008) Michael Föller et al.   FASEB JOURNAL

Survival of red blood cells after transfusion: a comparison between red cells concentrates of different storage periods

(2008) Marleen Luten et al.   TRANSFUSION