IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

(2019) Yu Cao et al.   Nature Communications

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

(2019) Maria Gutierrez-Arcelus et al.   Nature Communications

Integrative single-cell analysis

(2019) Tim Stuart et al.   NATURE REVIEWS GENETICS

Global Disease Burden Estimates of Respiratory Syncytial Virus–Associated Acute Respiratory Infection in Older Adults in 2015: A Systematic Review and Meta-Analysis

(2019) Ting Shi et al.   JOURNAL OF INFECTIOUS DISEASES

TCF-1 limits the formation of Tc17 cells via repression of the MAF–RORγt axis

(2019) Lisa A. Mielke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses

(2019) Aisling O’Brien et al.   JOURNAL OF IMMUNOLOGY

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Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation

(2018) Johanna Emgård et al.   IMMUNITY

HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

(2018) Akil Hammami et al.   Scientific Reports

Revealing the protective and pathogenic potential of MAIT cells

(2018) Criselle D’Souza et al.   MOLECULAR IMMUNOLOGY

MAIT cells protect against pulmonary Legionella longbeachae infection

(2018) Huimeng Wang et al.   Nature Communications

Tissue-resident MAIT cell populations in human oral mucosa exhibit an activated profile and produce IL-17

(2018) Michał J. Sobkowiak et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

(2018) Marion Salou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MAIT cells contribute to protection against lethal influenza infection in vivo

(2018) Bonnie van Wilgenburg et al.   Nature Communications

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

(2017) M. H. Al-Mossawi et al.   Nature Communications

Interleukin 32: a novel player in the control of infectious diseases

(2016) Fátima Ribeiro-Dias et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rapid and combined detection of Mycoplasma pneumoniae, Epstein–Barr virus and human cytomegalovirus using AllGlo quadruplex quantitative PCR

(2016) Yi Chen et al.   JOURNAL OF MEDICAL MICROBIOLOGY

MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation

(2016) A Gibbs et al.   Mucosal Immunology

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Multiple layers of transcriptional regulation by PLZF in NKT-cell development

(2016) Ai-Ping Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

(2015) Jellert T. Gaublomme et al.   CELL

Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation

(2015) Natalia B. Pikor et al.   IMMUNITY

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

(2015) Isabelle Magalhaes et al.   JOURNAL OF CLINICAL INVESTIGATION

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

(2015) Robert P. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases

(2014) N.-E. Serriari et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

The Rise and Fall of MAIT Cells with Age

(2014) L. J. Walker et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections

(2013) David Grimaldi et al.   INTENSIVE CARE MEDICINE

Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease

(2013) Helen C. Steel et al.   MEDIATORS OF INFLAMMATION

MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection

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T helper 17 cells are involved in the local and systemic inflammatory response in community-acquired pneumonia

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(2012) Andrei-Alin Popescu et al.   BIOINFORMATICS

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

(2012) E. Leeansyah et al.   BLOOD

Early and nonreversible decrease of CD161++/MAIT cells in HIV infection

(2012) C. Cosgrove et al.   BLOOD

Polyclonal Mucosa-Associated Invariant T Cells Have Unique Innate Functions in Bacterial Infection

(2012) Wei-Jen Chua et al.   INFECTION AND IMMUNITY

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

STAT3-Mediated IL-17 Production by Postseptic T Cells Exacerbates Viral Immunopathology of the Lung

(2012) Sumanta Mukherjee et al.   SHOCK

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Causes of deaths in children younger than 5 years in China in 2008

(2010) Igor Rudan et al.   LANCET

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

The AP-1 transcription factor Batf controls TH17 differentiation

(2009) Barbara U. Schraml et al.   NATURE

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE