Tepary Bean (Phaseolus acutifolius) Lectins Induce Apoptosis and Cell Arrest in G0/G1 by P53(Ser46) Phosphorylation in Colon Cancer Cells

Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death

(2019) Sujit K. Bhutia et al.   PHARMACOLOGICAL RESEARCH

Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road

(2019) Magdalena C. Liebl et al.   BIOESSAYS

Pea lectin inhibits cell growth by inducing apoptosis in SW480 and SW48 cell lines

(2018) Farhadul Islam et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Moringa oleifera seed lectin inhibits Ehrlich ascites carcinoma cell growth by inducing apoptosis through the regulation of Bak and NF-κB gene expression

(2018) A.K.M. Asaduzzaman et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A mitogenic lectin from Rhizoctonia bataticola arrests growth, inhibits metastasis, and induces apoptosis in human colon epithelial cancer cells

(2018) Prajna Hegde et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation and function of p53: A perspective from Drosophila studies

(2018) María Clara Ingaramo et al.   MECHANISMS OF DEVELOPMENT

Plant Lectins as Medical Tools against Digestive System Cancers

(2017) Laura Estrada-Martínez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phaseolus acutifolius Lectin Fractions Exhibit Apoptotic Effects on Colon Cancer: Preclinical Studies Using Dimethilhydrazine or Azoxi-Methane as Cancer Induction Agents

(2017) Ulisses Moreno-Celis et al.   MOLECULES

Anti-cancer effects of enteric-coated polymers containing mistletoe lectin in murine melanoma cells in vitro and in vivo

(2015) Seung-Yeon Han et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53

(2015) X. Song et al.   MOLECULAR CANCER RESEARCH

Lectins with Potential for Anti-Cancer Therapy

(2015) Tammy Yau et al.   MOLECULES

Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy

(2014) Q.-L. Jiang et al.   CELL PROLIFERATION

Glycosylation-Dependent Interactions of C-Type Lectin DC-SIGN with Colorectal Tumor-Associated Lewis Glycans Impair the Function and Differentiation of Monocyte-Derived Dendritic Cells

(2014) M. Nonaka et al.   JOURNAL OF IMMUNOLOGY

Imaging Caspase-3 Activation as a Marker of Apoptosis-Targeted Treatment Response in Cancer

(2014) Delphine L. Chen et al.   MOLECULAR IMAGING AND BIOLOGY

Cytotoxic and Antiproliferative Effect of Tepary Bean Lectins on C33-A, MCF-7, SKNSH, and SW480 Cell Lines

(2014) Carmen Valadez-Vega et al.   MOLECULES

Antitumor effects of concanavalin A and Sophora flavescens lectin in vitro and in vivo

(2013) Zheng Shi et al.   ACTA PHARMACOLOGICA SINICA

Pea lectin inhibits growth of Ehrlich ascites carcinoma cells by inducing apoptosis and G2/M cell cycle arrest in vivo in mice

(2013) Syed Rashel Kabir et al.   PHYTOMEDICINE

Assessing dose-dependent differences in DNA-damage, p53 response and genotoxicity for quercetin and curcumin

(2013) Bin Sun et al.   TOXICOLOGY IN VITRO

A new development of triterpene acid-containing extracts from Viscum album L. displays synergistic induction of apoptosis in acute lymphoblastic leukaemia

(2012) C. I. Delebinski et al.   CELL PROLIFERATION

Purified mulberry leaf lectin (MLL) induces apoptosis and cell cycle arrest in human breast cancer and colon cancer cells

(2012) Mundekkad Deepa et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effects of Tepary Bean (Phaseolus acutifolius) Protease Inhibitor and Semipure Lectin Fractions on Cancer Cells

(2012) Teresa García-Gasca et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

A new Phaseolus vulgaris lectin induces selective toxicity on human liver carcinoma Hep G2 cells

(2011) Evandro Fei Fang et al.   ARCHIVES OF TOXICOLOGY

Plant lectins: Targeting programmed cell death pathways as antitumor agents

(2011) Lei-lei Fu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Detection of Cytotoxic Activity of Lectin on Human Colon Adenocarcinoma (Sw480) and Epithelial Cervical Carcinoma (C33-A)

(2011) Carmen Valadez-Vega et al.   MOLECULES

Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma

(2011) J de Lange et al.   ONCOGENE

Role of p53 Serine 46 in p53 Target Gene Regulation

(2011) Leonie Smeenk et al.   PLoS One

A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics

(2010) Haike Ghazarian et al.   ACTA HISTOCHEMICA

Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras–Raf and PI3K–Akt signaling pathways

(2010) Bo Liu et al.   BIOCHIMIE

p53 Plays an Important Role in Cell Fate Determination after Exposure to Microcystin-LR

(2010) Shota Takumi et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Clematis montana lectin, a novel mannose-binding lectin from traditional Chinese medicine with antiviral and apoptosis-inducing activities

(2009) Hao Peng et al.   PEPTIDES

Antiproliferation and apoptosis of human tumor cell lines by a lectin (AMML) of Astragalus mongholicus

(2009) Qiaojuan Yan et al.   PHYTOMEDICINE

p53: A Guide to Apoptosis

(2008) Erik Meulmeester et al.   CURRENT CANCER DRUG TARGETS

A novel sialic acid-specific lectin from Phaseolus coccineus seeds with potent antineoplastic and antifungal activities

(2008) Jing Chen et al.   PHYTOMEDICINE