Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4

Ginsenoside Rb1 Blocks Ritonavir-Induced Oxidative Stress and eNOS Downregulation through Activation of Estrogen Receptor-Beta and Upregulation of SOD in Human Endothelial Cells

(2019) Jian-Ming Lü et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective Effect of Ginsenoside Rg1 on Oxidative Damage Induced by Hydrogen Peroxide in Chicken Splenic Lymphocytes

(2019) Shicheng Bi et al.   Oxidative Medicine and Cellular Longevity

Chemical Structures and Pharmacological Profiles of Ginseng Saponins

(2019) Ze-Yu Shi et al.   MOLECULES

Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells

(2019) Meichen Liu et al.   MOLECULES

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor

(2018) Duy-Khanh Dang et al.   Journal of Neuroinflammation

Effects of ginsenoside Rb1 on oxidative stress injury in rat spinal cords by regulating the eNOS/Nrf2/HO‑1 signaling pathway

(2018) Xinwei Liu et al.   Experimental and Therapeutic Medicine

Ginsenoside Rb2 suppresses the glutamate-mediated oxidative stress and neuronal cell death in HT22 cells

(2018) Dong Hoi Kim et al.   Journal of Ginseng Research

Ginsenoside Re Protects Trimethyltin-Induced Neurotoxicity via Activation of IL-6-Mediated Phosphoinositol 3-Kinase/Akt Signaling in Mice

(2017) Thu-Hien Thi Tu et al.   NEUROCHEMICAL RESEARCH

Role of ginsenosides, the main active components of Panax ginseng , in inflammatory responses and diseases

(2017) Ji Hye Kim et al.   Journal of Ginseng Research

Oxidative stress and cellular pathologies in Parkinson’s disease

(2017) Lesly Puspita et al.   Molecular Brain

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Ginsenoside Rg1 Protects against Oxidative Stress-induced Neuronal Apoptosis through Myosin IIA-actin Related Cytoskeletal Reorganization

(2016) Yan Wang et al.   International Journal of Biological Sciences

Glutathione peroxidase 4: a new player in neurodegeneration?

(2016) B R Cardoso et al.   MOLECULAR PSYCHIATRY

Ginsenoside Rd attenuates Aβ25–35-induced oxidative stress and apoptosis in primary cultured hippocampal neurons

(2015) Juan-fang Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Neuroprotective effects of pretreatment of ginsenoside Rb1 on severe cerebral ischemia-induced injuries in aged mice: Involvement of anti-oxidant signaling

(2015) Xiao Dong et al.   Geriatrics & Gerontology International

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Baicalein Prevents 6-Hydroxydopamine-Induced Mitochondrial Dysfunction in SH-SY5Y Cells via Inhibition of Mitochondrial Oxidation and Up-Regulation of DJ-1 Protein Expression

(2013) Yue-Hua Wang et al.   MOLECULES

Ginsenoside Rb1 Prevents MPP+-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK

(2012) Ryo Hashimoto et al.   Evidence-based Complementary and Alternative Medicine

Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

(2012) Si-Eun Yoo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential Toxicity of 6-Hydroxydopamine in SH-SY5Y Human Neuroblastoma Cells and Rat Brain Mitochondria: Protective Role of Catalase and Superoxide Dismutase

(2012) Javier Iglesias-González et al.   NEUROCHEMICAL RESEARCH

Neuroprotective effect of 20(R)-ginsenoside Rg3 against transient focal cerebral ischemia in rats

(2012) Bo He et al.   NEUROSCIENCE LETTERS

Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt

(2011) Chun Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Induction of Glutathione Peroxidase 4 Expression during Enterocytic Cell Differentiation

(2011) Bodo Speckmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease

(2011) E. Ilijic et al.   NEUROBIOLOGY OF DISEASE

Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease

(2009) Min-Hyuk Yoo et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria

(2009) Hanyu Liang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Ginsenosides on Organogenesis and Expression of Glutathione Peroxidase Genes in Cultured Rat Embryos

(2008) Se-Ra LEE et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT