Revisiting the Structure and Chemistry of 3(5)-Substituted Pyrazoles

Recent synthetic methodologies for pyrazolo[1,5-a]pyrimidine

(2019) Mohamed A. Salem et al.   SYNTHETIC COMMUNICATIONS

A new practical synthesis of 3-amino-substituted 5-aminopyrazoles and their tautomerism

(2019) Felicia Phei Lin Lim et al.   TETRAHEDRON

Annular Tautomerism of 3(5)-Disubstituted-1H-pyrazoles with Ester and Amide Groups

(2019) Anna Kusakiewicz-Dawid et al.   MOLECULES

5-Aminopyrazole as precursor in design and synthesis of fused pyrazoloazines

(2018) Ranjana Aggarwal et al.   Beilstein Journal of Organic Chemistry

Design, synthesis and biological evaluation of novel 3-substituted pyrazolopyrimidine derivatives as potent Bruton’s tyrosine kinase (BTK) inhibitors

(2018) Nan Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

(2018) Khalid Karrouchi et al.   MOLECULES

Design, synthesis, docking, and antimicrobial evaluation of some novel pyrazolo[1,5-a]pyrimidines and their corresponding cycloalkane ring-fused derivatives as purine analogs

(2018) Amira EM Abdallah et al.   Drug Design Development and Therapy

A review on diverse heterocyclic compounds as the privileged scaffolds in antimalarial drug discovery

(2018) Piyush N. Kalaria et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

5-Amino-pyrazoles: potent reagents in organic and medicinal synthesis

(2018) Ahmad Shaabani et al.   MOLECULAR DIVERSITY

Synthesis of Some Pyrimidine, Pyrazole, and Pyridine Derivatives and Their Reactivity Descriptors

(2018) Nour E. A. Abd El-Sattar et al.   Journal of Chemistry

Aminoazole-Based Diversity-Oriented Synthesis of Heterocycles

(2018) Maryna V. Murlykina et al.   Frontiers in Chemistry

An insight on synthetic and medicinal aspects of pyrazolo[1,5- a ]pyrimidine scaffold

(2017) Srinivasulu Cherukupalli et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-Step Synthesis of Fully Functionalized Pyrazolo[3,4-b]pyridines via Isobenzofuranone Ring Opening

(2017) Andrés Charris-Molina et al.   JOURNAL OF ORGANIC CHEMISTRY

Regioselective Synthesis, NMR, and Crystallographic Analysis of N1-Substituted Pyrazoles

(2017) Adrian Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

On the ordeal of quinolone preparation via cyclisation of aryl-enamines; synthesis and structure of ethyl 6-methyl-7-iodo-4-(3-iodo-4-methylphenoxy)-quinoline-3-carboxylate

(2017) Pedro Horta et al.   PURE AND APPLIED CHEMISTRY

Computational Methods to Predict the Regioselectivity of Electrophilic Aromatic Substitution Reactions of Heteroaromatic Systems

(2016) Monika Kruszyk et al.   JOURNAL OF ORGANIC CHEMISTRY

The1H NMR spectrum of pyrazole in a nematic phase

(2016) Patricio Provasi et al.   MAGNETIC RESONANCE IN CHEMISTRY

Catalyst-free Biginelli-type synthesis of new functionalized 4,7-dihydropyrazolo[1,5-a]pyrimidines

(2016) Maksim A. Kolosov et al.   NEW JOURNAL OF CHEMISTRY

The kinetics of water-assisted tautomeric 1,2-proton transfer in azoles: a computational approach

(2016) Wojciech P. Oziminski   STRUCTURAL CHEMISTRY

Chemistry of antipyrine

(2016) Khaled M. Elattar et al.   SYNTHETIC COMMUNICATIONS

Computational Study of Proton Transfer in Tautomers of 3- and 5-Hydroxypyrazole Assisted by Water

(2015) Cristina Trujillo et al.   CHEMPHYSCHEM

Synthesis, structure and biological activity of 3(5)-trifluoromethyl-1H-pyrazoles derived from hemicurcuminoids

(2015) Carla I. Nieto et al.   JOURNAL OF MOLECULAR STRUCTURE

Quinolone–Hydroxyquinoline Tautomerism in Quinolone 3-Esters. Preserving the 4-Oxoquinoline Structure To Retain Antimalarial Activity

(2015) Pedro Horta et al.   JOURNAL OF ORGANIC CHEMISTRY

Tetrazolium Compounds: Synthesis and Applications in Medicine

(2015) Cheng-Xi Wei et al.   MOLECULES

A theoretical study of the gas phase (proton affinity) and aqueous (pKa) basicity of a series of 150 pyrazoles

(2015) Marta Marín-Luna et al.   NEW JOURNAL OF CHEMISTRY

Greener and Expeditious Synthesis of Fused Six-MemberedN,N-Heterocycles Using Microwave Irradiation

(2015) Navjeet Kaur   SYNTHETIC COMMUNICATIONS

Biologically Driven Synthesis of Pyrazolo[3,4-d]pyrimidines As Protein Kinase Inhibitors: An Old Scaffold As a New Tool for Medicinal Chemistry and Chemical Biology Studies

(2014) Silvia Schenone et al.   CHEMICAL REVIEWS

A comprehensive review on synthetic approach for antimalarial agents

(2014) Ajay Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure and tautomerism of 4-substituted 3(5)-aminopyrazoles in solution and in the solid state: NMR study and Ab initio calculations

(2014) E. E. Emelina et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Pyrazole Derivatives Possessing Anticancer Activity: Current Status

(2014) Simpal Kumari et al.   SYNTHETIC COMMUNICATIONS

Pyrazole scaffold: A remarkable tool in the development of anticancer agents

(2013) Harish Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pyrazole containing natural products: Synthetic preview and biological significance

(2013) Vinod Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Applications of Triazole Derivatives – A Review

(2013) S. Sathish Kumar et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Theoretical studies on tautomerism of 1H-pyrazole-5-thiol

(2013) Alireza Salimi Beni et al.   STRUCTURAL CHEMISTRY

Utility of 5-Amino-1-phenyl-1H-pyrazole-4-carboxamide in Heterocyclic Synthesis

(2013) Ahmed El-Mekabaty   SYNTHETIC COMMUNICATIONS

Theoretical studies on the effect of substituent in the proton transfer reaction of 4-substituted pyrazoles

(2013) Alireza Najafi Chermahini et al.   Computational and Theoretical Chemistry

Pyrazoles as Promising Scaffold for the Synthesis of Anti-Inflammatory and/or Antimicrobial Agent: A Review

(2012) Adnan A. Bekhit et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Nitrogen-Rich Azoles as Ligand Spacers in Coordination Polymers

(2011) Shi-Qiang Bai et al.   Chemistry-An Asian Journal

Recent Advances in the Chemistry of Pyrazoles. Properties, Biological Activities, and Syntheses

(2011) Andreas Schmidt et al.   CURRENT ORGANIC CHEMISTRY

Tautomerism in drug discovery

(2010) Alan R. Katritzky et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Pyrazoles and pyrazolides—flexible synthons in self-assembly

(2009) Malcolm A. Halcrow   DALTON TRANSACTIONS

Pyrazole Complexes and Supramolecular Chemistry

(2009) Julio Pérez et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Let’s not forget tautomers

(2009) Yvonne Connolly Martin   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis of some novel pyrazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1,5-a]pyrimidine, pyrido[2,3-d]pyrimidine, pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives incorporating a thiazolo[3,2-a]benzimidazole moiety

(2009) Hatem A. Abdel-Aziz et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

A theoretical comparison of the chemical shifts of three related heterocycles: 1H-pyrazoles, 1H-1,2,4-triazoles and 1H-1,2,4-diazaphospholes

(2009) Ibon Alkorta et al.   JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM

A Simple, Modular Method for the Synthesis of 3,4,5-Trisubstituted Pyrazoles

(2008) Mark McLaughlin et al.   JOURNAL OF ORGANIC CHEMISTRY

1H,13C NMR, X-ray and conformational studies of new 1-alkyl-3-benzoyl-pyrazole and 1-alkyl-3-benzoyl-pyrazoline derivatives

(2008) Luisa C. López-Cara et al.   MAGNETIC RESONANCE IN CHEMISTRY

13C and15N NMR chemical shifts of 1-(2′,4′-dinitrophenyl) and 1-(2′,4′,6′-trinitrophenyl) pyrazoles in the solid state and in solution

(2008) M. Ángeles García et al.   MAGNETIC RESONANCE IN CHEMISTRY

Synthesis of 5-Substituted 3-Amino-1H-Pyrazole-4-Carbonitriles as Precursors for Microwave Assisted Regiospecific Syntheses of Pyrazolo[1,5-a]Pyrimidines

(2008) Fawzia Al-Qalaf et al.   MOLECULES

A molecular balance to measure the strength of N–H⋯π hydrogen bonds based on the tautomeric equilibria of C-benzylphenyl substituted NH-pyrazoles

(2008) Pilar Cornago et al.   TETRAHEDRON

Synthesis and solvatochromic properties of 3,6-bis-hetarylazo dyes derived from pyrazolo[1,5-a]pyrimidine

(2007) Pi Chen Tsai et al.   DYES AND PIGMENTS

Theoretical study on molecular structures, intramolecular proton transfer reaction, and solvent effects of 1-phenyl-3-methyl-4-(6-hydro-4-amino-5-sulfo-2,3-pyrazine)-pyrazole-5-one

(2007) He Lin et al.   JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM