Programming Escherichia coli to function as a digital display

Future systems and control research in synthetic biology

(2018) Domitilla Del Vecchio et al.   ANNUAL REVIEWS IN CONTROL

Engineered promoters enable constant gene expression at any copy number in bacteria

(2018) Thomas H Segall-Shapiro et al.   NATURE BIOTECHNOLOGY

Cellular checkpoint control using programmable sequential logic

(2018) Lauren B. Andrews et al.   SCIENCE

Predicting Transcriptional Output of Synthetic Multi-input Promoters

(2018) David M. Zong et al.   ACS Synthetic Biology

Dynamic control of endogenous metabolism with combinatorial logic circuits

(2018) Felix Moser et al.   Molecular Systems Biology

Predicting how evolution will beat us

(2018) Tom Ellis   Microbial Biotechnology

Digital logic circuits in yeast with CRISPR-dCas9 NOR gates

(2017) Miles W. Gander et al.   Nature Communications

Insulated transcriptional elements enable precise design of genetic circuits

(2017) Yeqing Zong et al.   Nature Communications

Resource Competition Shapes the Response of Genetic Circuits

(2017) Yili Qian et al.   ACS Synthetic Biology

Reducing DNA context dependence in bacterial promoters

(2017) Swati B. Carr et al.   PLoS One

The best of both worlds: reaping the benefits from mammalian and bacterial therapeutic circuits

(2016) Daniel Bojar et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Recognizing and engineering digital-like logic gates and switches in gene regulatory networks

(2016) Robert W Bradley et al.   CURRENT OPINION IN MICROBIOLOGY

Overloaded and stressed: whole-cell considerations for bacterial synthetic biology

(2016) Olivier Borkowski et al.   CURRENT OPINION IN MICROBIOLOGY

Creating Single-Copy Genetic Circuits

(2016) Jeong Wook Lee et al.   MOLECULAR CELL

Antisense transcription as a tool to tune gene expression

(2016) J. A. Brophy et al.   Molecular Systems Biology

The role of repressor kinetics in relief of transcriptional interference between convergent promoters

(2016) Nan Hao et al.   NUCLEIC ACIDS RESEARCH

Genetic circuit design automation

(2016) A. A. K. Nielsen et al.   SCIENCE

Quantifying cellular capacity identifies gene expression designs with reduced burden

(2015) Francesca Ceroni et al.   NATURE METHODS

Memory and Combinatorial Logic Based on DNA Inversions: Dynamics and Evolutionary Stability

(2015) Jesus Fernandez-Rodriguez et al.   ACS Synthetic Biology

Predicting the Genetic Stability of Engineered DNA Sequences with the EFM Calculator

(2015) Benjamin R. Jack et al.   ACS Synthetic Biology

A Rule-Based Design Specification Language for Synthetic Biology

(2015) Ernst Oberortner et al.   ACM Journal on Emerging Technologies in Computing Systems

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

(2014) Alexander A. Green et al.   CELL

Synthetic analog and digital circuits for cellular computation and memory

(2014) Oliver Purcell et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bacterial growth: global effects on gene expression, growth feedback and proteome partition

(2014) Stefan Klumpp et al.   CURRENT OPINION IN BIOTECHNOLOGY

Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks

(2014) A. A. Nielsen et al.   Molecular Systems Biology

A load driver device for engineering modularity in biological networks

(2014) Deepak Mishra et al.   NATURE BIOTECHNOLOGY

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

Road rules for traffic on DNA—systematic analysis of transcriptional roadblockingin vivo

(2014) Nan Hao et al.   NUCLEIC ACIDS RESEARCH

Molecular basis of transcription pausing

(2014) J. W. Roberts   SCIENCE

Genomic mining of prokaryotic repressors for orthogonal logic gates

(2013) Brynne C Stanton et al.   Nature Chemical Biology

Characterization of 582 natural and synthetic terminators and quantification of their design constraints

(2013) Ying-Ja Chen et al.   NATURE METHODS

Amplifying Genetic Logic Gates

(2013) J. Bonnet et al.   SCIENCE

Retroactivity Controls the Temporal Dynamics of Gene Transcription

(2013) Shridhar Jayanthi et al.   ACS Synthetic Biology

Visualization of Evolutionary Stability Dynamics and Competitive Fitness of Escherichia coli Engineered with Randomized Multigene Circuits

(2013) Sean C. Sleight et al.   ACS Synthetic Biology

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

Biomolecular computing systems: principles, progress and potential

(2012) Yaakov Benenson   NATURE REVIEWS GENETICS

Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology

(2011) Baojun Wang et al.   Nature Communications

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

Interdependence of Cell Growth and Gene Expression: Origins and Consequences

(2010) M. Scott et al.   SCIENCE

Designing and engineering evolutionary robust genetic circuits

(2010) Sean C Sleight et al.   Journal of Biological Engineering

Emergent bistability by a growth-modulating positive feedback circuit

(2009) Cheemeng Tan et al.   Nature Chemical Biology

Nonspecific DNA-Protein Interaction: Why Proteins Can Diffuse along DNA

(2009) Vincent Dahirel et al.   PHYSICAL REVIEW LETTERS

Measuring the activity of BioBrick promoters using an in vivo reference standard

(2009) Jason R Kelly et al.   Journal of Biological Engineering

Modular cell biology: retroactivity and insulation

(2008) Domitilla Del Vecchio et al.   Molecular Systems Biology

Refinement and standardization of synthetic biological parts and devices

(2008) Barry Canton et al.   NATURE BIOTECHNOLOGY