A variant near DHCR24 associates with microstructural properties of white matter and peripheral lipid metabolism in adolescents

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(2019) Nadine Parker et al.   CEREBRAL CORTEX

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

(2018) Sven J. van der Lee et al.   Alzheimers & Dementia

NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects

(2018) Eeva Sliz et al.   HUMAN MOLECULAR GENETICS

Visceral fat-related systemic inflammation and the adolescent brain: a mediating role of circulating glycerophosphocholines

(2018) Catriona Syme et al.   INTERNATIONAL JOURNAL OF OBESITY

Is Seladin-1 Really a Selective Alzheimer's Disease Indicator?

(2018) Laura J. Sharpe et al.   JOURNAL OF ALZHEIMERS DISEASE

ComPaSS-GWAS: A method to reduce type I error in genome-wide association studies when replication data are not available

(2018) Jeremy A. Sabourin et al.   GENETIC EPIDEMIOLOGY

Comprehensive functional genomic resource and integrative model for the human brain

(2018) Daifeng Wang et al.   SCIENCE

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD

(2017) Panu K. Luukkonen et al.   JOURNAL OF HEPATOLOGY

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

(2017) Henna Martiskainen et al.   Journal of Neuroinflammation

Obesity-Induced Neuroinflammation: Beyond the Hypothalamus

(2017) Owein Guillemot-Legris et al.   TRENDS IN NEUROSCIENCES

Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study

(2017) Kim V. E. Braun et al.   Clinical Epigenetics

Glycerophosphocholine Metabolites and Cardiovascular Disease Risk Factors in AdolescentsClinical Perspective

(2016) Catriona Syme et al.   CIRCULATION

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

(2016) B. B. Lake et al.   SCIENCE

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

Practical impacts of genomic data “cleaning” on biological discovery using surrogate variable analysis

(2015) Andrew E. Jaffe et al.   BMC BIOINFORMATICS

The Role of Neuroinflammation in Dementias

(2015) Giuseppe Pasqualetti et al.   Current Neurology and Neuroscience Reports

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

(2015) Ellen W. Demerath et al.   HUMAN MOLECULAR GENETICS

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

(2015) Daniel I Swerdlow et al.   LANCET

High fat challenges with different fatty acids affect distinct atherogenic gene expression pathways in immune cells from lean and obese subjects

(2015) Diederik Esser et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer’s disease pathogenesis

(2015) Li Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seladin-1/DHCR24 Is Neuroprotective by Associating EAAT2 Glutamate Transporter to Lipid Rafts in Experimental Stroke

(2015) Macarena Hernández-Jiménez et al.   STROKE

Cholesterol metabolism and homeostasis in the brain

(2015) Juan Zhang et al.   Protein & Cell

Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation

(2015) J Chiappelli et al.   Translational Psychiatry

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

(2015) Scott C. Ritchie et al.   Cell Systems

Using population isolates in genetic association studies

(2014) K. Hatzikotoulas et al.   Briefings in Functional Genomics

To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase

(2014) Gopal Kedihitlu Marathe et al.   JOURNAL OF LIPID RESEARCH

Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells

(2014) Daisuke Hishikawa et al.   JOURNAL OF LIPID RESEARCH

REST and stress resistance in ageing and Alzheimer’s disease

(2014) Tao Lu et al.   NATURE

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Adiposity is associated with structural properties of the adolescent brain

(2014) Deborah H. Schwartz et al.   NEUROIMAGE

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition

(2013) Xin Rong et al.   Cell Metabolism

Visceral fat is associated with lower executive functioning in adolescents

(2013) D H Schwartz et al.   INTERNATIONAL JOURNAL OF OBESITY

Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis

(2013) Winnie Luu et al.   JOURNAL OF LIPID RESEARCH

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Lysoglycerophospholipids in chronic inflammatory disorders: The PLA2/LPC and ATX/LPA axes

(2012) Ioanna Sevastou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

Phosphatidylcholine biosynthesis and lipoprotein metabolism

(2011) Laura K. Cole et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

(2011) Daniah Trabzuni et al.   JOURNAL OF NEUROCHEMISTRY

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Reply

(2010) Stéphanie Debette et al.   ANNALS OF NEUROLOGY

ProbABEL package for genome-wide association analysis of imputed data

(2010) Yurii S Aulchenko et al.   BMC BIOINFORMATICS

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

3β-Hydroxysteroid-Δ24 Reductase Is a Hydrogen Peroxide Scavenger, Protecting Cells from Oxidative Stress-Induced Apoptosis

(2008) Xiuli Lu et al.   ENDOCRINOLOGY

DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis

(2008) Caroline Hild Jakobsen et al.   JOURNAL OF LIPID RESEARCH