Targeting signaling pathways of VEGFR1 and VEGFR2 as a potential target in the treatment of breast cancer

A cyclic peptide reproducing the α1 helix of VEGF-B binds to VEGFR-1 and VEGFR-2 and inhibits angiogenesis and tumor growth

(2019) Elham Assareh et al.   BIOCHEMICAL JOURNAL

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

(2018) Ramesh Butti et al.   Molecular Cancer

Epithelial-mesenchymal transition in breast epithelial cells treated with cadmium and the role of Snail

(2018) Zhengxi Wei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dual blockade of VEGFR1 and VEGFR2 by a novel peptide abrogates VEGF-driven angiogenesis, tumor growth, and metastasis through PI3K/AKT and MAPK/ERK1/2 pathway

(2018) Afsaneh Sadremomtaz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A peptide mimicking the binding sites of VEGF-A and VEGF-B inhibits VEGFR-1/-2 driven angiogenesis, tumor growth and metastasis

(2018) Maryam Farzaneh Behelgardi et al.   Scientific Reports

VEGF/NRP-1 axis promotes progression of breast cancer via enhancement of epithelial-mesenchymal transition and activation of NF-κB and β-catenin

(2016) Minna Luo et al.   CANCER LETTERS

The Contribution of Angiogenesis to the Process of Metastasis

(2015) Diane R. Bielenberg et al.   CANCER JOURNAL

Expression and prognostic significance of VEGFR-2 in breast cancer

(2015) Ji-Dong Yan et al.   PATHOLOGY RESEARCH AND PRACTICE

The Emerging Regulation of VEGFR-2 in Triple-Negative Breast Cancer

(2015) Xiaoxia Zhu et al.   Frontiers in Endocrinology

The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

Snail Promotes Epithelial Mesenchymal Transition in Breast Cancer Cells in Part via Activation of Nuclear ERK2

(2014) Bethany N. Smith et al.   PLoS One

FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells

(2014) Ying-Li Hu et al.   Scientific Reports

PAK1 Regulates Breast Cancer Cell Invasion through Secretion of Matrix Metalloproteinases in Response to Prolactin and Three-Dimensional Collagen IV

(2013) Leah Rider et al.   MOLECULAR ENDOCRINOLOGY

The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1α expression

(2013) JAE HO LEE et al.   ONCOLOGY REPORTS

Vascular Endothelial Growth Factor Receptor-1 Activation Promotes Migration and Invasion of Breast Cancer Cells through Epithelial-Mesenchymal Transition

(2013) Qian Ning et al.   PLoS One

FAK inhibition decreases cell invasion, migration and metastasis in MYCN amplified neuroblastoma

(2012) Michael L. Megison et al.   CLINICAL & EXPERIMENTAL METASTASIS

RACK1 Regulates VEGF/Flt1-mediated Cell Migration via Activation of a PI3K/Akt Pathway

(2011) Feng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

(2010) Alexander T Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes

(2009) Johanna Ivaska et al.   CELL AND TISSUE RESEARCH