A peptide mimicking the binding sites of VEGF-A and VEGF-B inhibits VEGFR-1/-2 driven angiogenesis, tumor growth and metastasis

Dual blockade of VEGFR1 and VEGFR2 by a novel peptide abrogates VEGF-driven angiogenesis, tumor growth, and metastasis through PI3K/AKT and MAPK/ERK1/2 pathway

(2018) Afsaneh Sadremomtaz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification of Peptidic Antagonists of Vascular Endothelial Growth Factor Receptor 1 by Scanning the Binding Epitopes of Its Ligands

(2017) Lei Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response

(2016) Lucia De Rosa et al.   Scientific Reports

FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis

(2015) Bin-Zhi Qian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small Molecule Modulators of Protein–Protein Interactions: Selected Case Studies

(2014) Madhu Aeluri et al.   CHEMICAL REVIEWS

Design and Synthesis of C-Terminal Modified Cyclic Peptides as VEGFR1 Antagonists

(2014) Lei Wang et al.   MOLECULES

Metabolic Impact of Anti-Angiogenic Agents on U87 Glioma Cells

(2014) Tanja Mesti et al.   PLoS One

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

Expression of VEGF Receptors on Endothelial Cells in Mouse Skeletal Muscle

(2012) Princess I. Imoukhuede et al.   PLoS One

Characterization of a Designed Vascular Endothelial Growth Factor Receptor Antagonist Helical Peptide with Antiangiogenic Activity in Vivo

(2011) Anna Basile et al.   JOURNAL OF MEDICINAL CHEMISTRY

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

Structural Insights into the Binding of Vascular Endothelial Growth Factor-B by VEGFR-1D2

(2010) Shalini Iyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical and Structural Analysis of the Binding Determinants of a Vascular Endothelial Growth Factor Receptor Peptidic Antagonist

(2010) Benoit Gautier et al.   JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic antibodies: successes, limitations and hopes for the future

(2009) Patrick Chames et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer

(2009) Christina L. Roland et al.   PLoS One