Gut metabolomics profiling of non-small cell lung cancer (NSCLC) patients under immunotherapy treatment

Daily consumption of orange juice from Citrus sinensis L. Osbeck cv. Cara Cara and cv. Bahia differently affects Gut Microbiota Profiling as unveiled by an integrated meta-omics approach

(2019) Elisa Brasili et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The potential of breath analysis to improve outcome for patients with lung cancer

(2019) Sophia Antoniou et al.   Journal of Breath Research

Exploring the emerging role of the microbiome in cancer immunotherapy

(2019) Jessica Fessler et al.   Journal for ImmunoTherapy of Cancer

Propionate-Producing Consortium Restores Antibiotic-Induced Dysbiosis in a Dynamic in vitro Model of the Human Intestinal Microbial Ecosystem

(2019) Racha El Hage et al.   Frontiers in Microbiology

Immune regulation by microbiome metabolites

(2018) Chang H. Kim   IMMUNOLOGY

The fecal metabolome as a functional readout of the gut microbiome

(2018) Jonas Zierer et al.   NATURE GENETICS

Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden

(2018) Matthew D. Hellmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diet, Microbiota and Gut-Lung Connection

(2018) Swadha Anand et al.   Frontiers in Microbiology

Characterisation of gut, lung, and upper airways microbiota in patients with non-small cell lung carcinoma

(2018) Rea Bingula et al.   MEDICINE

Gut microbiota signatures in cystic fibrosis: Loss of host CFTR function drives the microbiota enterophenotype

(2018) Pamela Vernocchi et al.   PLoS One

Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers

(2018) Vanessa L. Hale et al.   Genome Medicine

IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

Counterpoint: Successes in the Pursuit of Precision Medicine: Biomarkers Take Credit

(2017) Shumei Kato et al.   Journal of the National Comprehensive Cancer Network

First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer

(2017) David P. Carbone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

(2017) Diego Chowell et al.   SCIENCE

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

(2017) Arthur E. Frankel et al.   NEOPLASIA

Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer

(2017) Rea Bingula et al.   Journal of Oncology

Formation of propionate and butyrate by the human colonic microbiota

(2016) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

(2016) Krista Dubin et al.   Nature Communications

The deleterious metabolic and genotoxic effects of the bacterial metabolite p-cresol on colonic epithelial cells

(2015) Mireille Andriamihaja et al.   FREE RADICAL BIOLOGY AND MEDICINE

Towards microbial fermentation metabolites as markers for health benefits of prebiotics

(2015) Kristin A. Verbeke et al.   NUTRITION RESEARCH REVIEWS

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014

(2014) R. Salgado et al.   ANNALS OF ONCOLOGY

The emergent role of metabolic phenotyping in dynamic patient stratification

(2014) John C Lindon et al.   Expert Opinion on Drug Metabolism & Toxicology

Changes in the Bacterial Microbiota in Gut, Blood, and Lungs following Acute LPS Instillation into Mice Lungs

(2014) Marc A. Sze et al.   PLoS One

Improved Survival with T Cell Clonotype Stability After Anti-CTLA-4 Treatment in Cancer Patients

(2014) E. Cha et al.   Science Translational Medicine

Fecal Biomarkers of Intestinal Health and Disease in Children

(2014) Tamara Pang et al.   Frontiers in Pediatrics

Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma

(2013) Hui-Min Chen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 Induce Different Age-Related Metabolic Profiles Revealed by 1H-NMR Spectroscopy in Urine and Feces of Mice

(2013) Elisa Brasili et al.   JOURNAL OF NUTRITION

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

(2013) Paul J. McMurdie et al.   PLoS One

Urinary Volatile Compounds as Biomarkers for Lung Cancer

(2012) Yosuke HANAI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Integration of datasets from different analytical techniques to assess the impact of nutrition on human metabolome

(2012) Pamela Vernocchi et al.   Frontiers in Cellular and Infection Microbiology

Targeted Metabolomics for Biomarker Discovery

(2010) William J. Griffiths et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Urinary Volatile Compounds as Biomarkers for Lung Cancer: A Proof of Principle Study Using Odor Signatures in Mouse Models of Lung Cancer

(2010) Koichi Matsumura et al.   PLoS One

PyNAST: a flexible tool for aligning sequences to a template alignment

(2009) J. G. Caporaso et al.   BIOINFORMATICS

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

Metabolic Phenotyping in Health and Disease

(2008) Elaine Holmes et al.   CELL