Article
Oncology
Johnathan Drevik, Zafardjan Dalimov, Robert Uzzo, John Danella, Thomas Guzzo, Lawrence Belkoff, Jay Raman, Jeffrey Tomaszewski, Edouard Trabulsi, Adam Reese, Eric A. Singer, Kaynaat Syed, Bruce Jacobs, Andres Correa, Marc Smaldone, Serge Ginzburg
Summary: PSA density (PSAd) can be used to further risk-stratify PIRADs 3 lesions, potentially avoiding biopsies and opting for monitoring instead.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2022)
Article
Respiratory System
Jing Zhang, Jie-Ru Guo, Zan-Sheng Huang, Wan-Lei Fu, Xian-Li Wu, Na Wu, Wolfgang M. Kuebler, Felix J. F. Herth, Ye Fan
Summary: This study demonstrated that transbronchial mediastinal cryobiopsy monitored by endosonography is a safe and effective approach for diagnosing mediastinal lesions, with higher diagnostic yield compared to traditional needle aspiration techniques.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Amjad N. Kanj, William F. Young, Jay H. Ryu
Summary: This study aimed to better characterize the clinical features of mediastinal paragangliomas in order to optimize their diagnosis and treatment. The results showed that most mediastinal paragangliomas are located in the middle mediastinum and can be diagnosed noninvasively using a combination of clinical, biochemical, and radiological features.
RESPIRATORY MEDICINE
(2023)
Article
Communication
Lars E. F. Johannessen, Maja Nordtug, Marit Haldar
Summary: This article advances domestication theory by developing the concept of multi-site domestication. Using data from the implementation of AV1 in Norway, the article shows how domestication becomes more complex when it occurs across settings with different norms, rules, values, and logics.
INFORMATION COMMUNICATION & SOCIETY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hailey H. Choi, Amy L. Kotsenas, Joshua Vic Chen, Christina Bronsky, Christopher J. Roth, Marc D. Kohli
Summary: The study found that the utilization rate of patients viewing radiology images online is low, and it has minimal impact on radiologists' workflow. Most radiologists believe that patient image viewing does not affect their role, but there are concerns about potential confusion among patients.
JOURNAL OF DIGITAL IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maitray D. Patel, Thad Benefield, Katie N. Hunt, Courtney M. Tomblinson, Kamran Ali, Carolynn M. DeBenedectis, Eric England, Glenn C. Gaviola, Christopher P. Ho, Ann K. Jay, James M. Milburn, Seng Ong, Jessica B. Robbins, David S. Sarkany, Darel E. Heitkamp, Sheryl G. Jordan
Summary: By analyzing data from multiple institutions, the study found that Step 3 performance tiers can identify radiology residents at increased risk of Core examination failure and submean performance. Residents with lower Step 3 scores had higher Core examination failure rates, while Core performance improved with higher Step 3 quintiles.
ACADEMIC RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pierre Chambon, Tessa S. Cook, Curtis P. Langlotz
Summary: Building a document-level classifier for COVID-19 on radiology reports, using a fine-tuned BERT-like model initialized from RadBERT, has shown excellent performance. The classifier outperforms other biomedical pre-trainings and achieves a high macro-averaged F1-score on both X-ray and CT reports. The model is built using a multi-institutional dataset and incorporates various techniques for fine-tuning and hyperparameter optimization. Visualization tools and explainability methods are also provided to support the practical use of the model in the clinical setting.
JOURNAL OF DIGITAL IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gennaro D'Anna, Lorenzo Ugga, Renato Cuocolo, Melissa Mei Chen, Deborah Rachelle Shatzkes, Emin Turgut Tali, Amy Patel, Amy Louise Kotsenas, Johan Van Goethem, Tushar Garg, Joshua Adam Hirsch, Luis Marti-Bonmati, Frank Gaillard, Erik Ranschaert
Summary: This study explored perceptions and preferences regarding the conversion of in-person to virtual conferences. The majority of respondents had attended virtual conferences and expressed a desire to attend future virtual meetings. They preferred virtual conferences to last 2-3 days, with sessions of 2-4 hours. Respondents wanted significant fee reductions and the option to attend conferences both in-person and online. Educational sessions were deemed the most valuable aspect of virtual meetings, while the lack of networking and human contact was seen as a significant drawback. In the future, people expressed a preference for attending conferences in person for networking purposes, but in safer conditions.
EUROPEAN RADIOLOGY
(2022)
Article
Meteorology & Atmospheric Sciences
Zafar Adeel, Laura Bakkensen, Orlando Cabrera-Rivera, Ernesto Franco, Gregg M. Garfin, Renee A. McPherson, Karla Mendez, Xin Wen
Summary: Flooding is a devastating and costly natural hazard in Canada, Mexico, and the United States. Research is being conducted to understand the economic costs of floods and develop strategies to address their impacts and build resilient communities. However, there are significant challenges in terms of data consistency, research capacity, and language barriers across the three countries. The COVID-19 pandemic has further exacerbated these barriers. The paper suggests the establishment of new institutional mechanisms to enhance data gathering approaches in these countries.
BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Niusha Bavadian, Nelly Tan, Arthur J. Pesch, Kaley McMullen, Mike Haman, Francis Chan, Michael L. Volk, J. Paul Jacobson, Arun Krishnaraj
Summary: This study implemented a multi-institutional quality improvement project that obtained patient and provider feedback for radiology reports. Results showed that patients were more likely to be satisfied with reports and provide more feedback compared to providers, with feedback mainly focusing on the thoroughness, errors, and timeliness of reports.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2021)
Article
Veterinary Sciences
Cassie Van Hoof, Nicole A. Davis, Sheila Carrera-Justiz, Alisha D. Kahn, Steven De Decker, Nicholas J. Grapes, Michaela Beasley, John Du, Theresa E. Pancotto, Anna Sunol, Richard Shinn, Barry DeCicco, Erica Burkland, Harry Cridge
Summary: This retrospective study analyzed 386 dogs with discospondylitis to describe their clinical and imaging findings, etiology, treatment, and outcome. The study also assessed the diagnostic agreement between radiographs, CT, and MRI, and identified risk factors for relapse and progressive neurological deterioration. The results showed an overrepresentation of male dogs and L7-S1 disc involvement, with Staphylococcus as the predominant pathogen. There was fair agreement between radiographs and CT, but poor agreement between radiographs and MRI for diagnosing discospondylitis. Trauma was associated with an increased risk of relapse, while prior steroid therapy was associated with progressive neurological dysfunction.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2023)
Article
Clinical Neurology
Yavuz Samanci, M. Orbay Askeroglu, Ahmed M. Nabeel, Wael A. Reda, Sameh R. Tawadros, Khaled Abdelkarim, Amr M. N. El-Shehaby, Reem M. Emad, Andrew Legarreta, David Fernandes Cabral, Sharath Anand, Ajay Niranjan, L. Dade Lunsford, Manjul Tripathi, Narendra Kumar, Roman Liscak, Jaromir May, Cheng-chia Lee, Huai-che Yang, Nuria Martinez Moreno, Roberto Martinez Alvarez, Keiss Douri, David Mathieu, Stylianos Pikis, Georgios Mantziaris, Jason P. Sheehan, Kenneth Bernstein, Douglas Kondziolka, Selcuk Peker
Summary: This study evaluated the safety and efficacy of SRS in managing pediatric meningiomas. The results suggest that SRS may be a safe and effective treatment option for surgically inaccessible, recurrent, or residual pediatric meningiomas.
Article
Oncology
Yuri Tolkach, Vlado Ovtcharov, Alexey Pryalukhin, Marie-Lisa Eich, Nadine Therese Gaisa, Martin Braun, Abdukhamid Radzhabov, Alexander Quaas, Peter Hammerer, Ansgar Dellmann, Wolfgang Hulla, Michael C. Haffner, Henning Reis, Ibrahim Fahoum, Iryna Samarska, Artem Borbat, Hoa Pham, Axel Heidenreich, Sebastian Klein, George Netto, Peter Caie, Reinhard Buettner
Summary: This retrospective study validates a deep learning-based classifier for prostate cancer (PCA) detection and Gleason grading (AI tool) in biopsy samples. The AI tool showed high accuracy in tumor detection and had similar accuracy in Gleason grading compared to experienced pathologists.
NPJ PRECISION ONCOLOGY
(2023)
Review
Oncology
Guiyuan Zhang, Chunyong Wen, Bin Chen, Haitao Dai, Run Lin, Yonghui Huang, Xianhong Xiang
Summary: Hepatoid adenocarcinoma is a rare form of non-liver cancer that produces alpha-fetoprotein. Mediastinal hepatoid adenocarcinoma is extremely rare, and treatment options for this condition are limited. We present a case of successful treatment for mediastinal hepatoid adenocarcinoma using local-regional interventional therapy combined with systemic PD-1 inhibitor.
FRONTIERS IN ONCOLOGY
(2022)
Article
Pathology
Maria Del Carmen Rodriguez Pena, Sofia Canete-Portillo, Ali Amin, Manju Aron, Piergiuseppe Colombo, Roni Cox, Dilek Ertoy Baydar, Ivan Gallegos, Francesca Khani, Kvetoslava Michalova, Roberta Luciano, Hiroshi Miyamoto, Adeboye O. Osunkoya, Maria Rosaria Raspollini, Diego F. Sanchez, Federico Scarfo, Jeffrey S. So, Debra L. Zynger, Shi Wei, George J. Netto, Cristina Magi-Galluzzi
Summary: This international multi-institutional study aimed to validate the designation of metastatic disease for discontinuous involvement of spermatic cord soft tissue by testicular germ cell tumors, as introduced by the 8th edition of the AJCC Staging Manual. The study found significant differences between discontinuous and continuous cord involvement in various indicators.
Article
Rheumatology
Silvia Sartorelli, Guillaume Chassagnon, Pascal Cohen, Bertrand Dunogue, Xavier Puechal, Alexis Regent, Luc Mouthon, Loic Guillevin, Benjamin Terrier
Summary: Specific cardiomyopathy is frequent in EGPA, especially in ANCA-negative patients with high eosinophil counts. Long-term outcome was better than previously reported. Abnormal ECG and LGE on CMRI were associated with the occurrence of MACEs.
Article
Oncology
Peter G. Kallas, Mary Zalinger, James A. Sliwa, Mark K. Eskandari
Summary: Provider well-being is considered an important aspect of providing quality care, and the global COVID-19 pandemic has further highlighted its significance. This study examines the prevalence of burnout among oncologists in Ontario, Canada, and identifies key drivers of burnout within the healthcare system. The findings indicate that a significant number of participants experienced burnout, with working environment, job appreciation, workload control, and peer support being the main contributing factors.
JCO ONCOLOGY PRACTICE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marie-Pierre Revel, Nathanael Beeker, Raphael Porcher, Lea Jilet, Laure Fournier, Bastien Rance, Guillaume Chassagnon, Michaela Fontenay, Olivier Sanchez
Summary: This study aimed to identify the D-dimer levels that would allow the safe exclusion of pulmonary embolism (PE) in COVID-19 patients presenting to the emergency department. The results showed that the D-dimer levels were significantly higher in patients with PE compared to those without PE. Using specific D-dimer thresholds, PE could be safely ruled out and the number of unnecessary CTPA scans could be reduced.
EUROPEAN RADIOLOGY
(2022)
Letter
Respiratory System
Guillaume Chassagnon, Alienor Campredon, Maria Vakalopoulou, Pierre-Regis Burgel
EUROPEAN RESPIRATORY JOURNAL
(2022)
Article
Oncology
Nicolas Girard, Clemence Basse, Alexa Schrock, Shakti Ramkissoon, Keith Killian, Jeffrey S. Ross
Summary: This study provides comprehensive genomic profiling of thymic epithelial tumors in advanced disease, identifying clinically relevant genomic alterations and suggesting potential precision medicine approaches using targeted agents.
Article
Oncology
Conrad B. Falkson, Emily T. Vella, Peter M. Ellis, Donna E. Maziak, Yee C. Ung, Edward Yu
Summary: This guideline provides recommendations for the most effective therapy for patients with thymic epithelial tumors, including thymoma, thymic carcinoma, and thymic NETs. The recommendations cover surgical, radiation, and systemic treatments, based on the stage of disease using the TNM staging system.
JOURNAL OF THORACIC ONCOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Yafim Brodov, Shlomo Matezky, Eli Konen, Mattia Di Segni, Anan Younis, Ayas Massalha, Anat Berkovich, Arkadi Beytelman, Fernando Chernomordik, Orly Goitein
Summary: Elevated native T1 values can serve as independent predictors of obstructive non-infarct related arteries in STEMI patients. These findings suggest the presence of concomitant myocardial impairment in the non-infarct territories with obstructive coronary artery disease.
Review
Radiology, Nuclear Medicine & Medical Imaging
Guillaume Chassagnon, Constance De Margerie-Mellon, Maria Vakalopoulou, Rafael Marini, Trieu-Nghi Hoang-Thi, Marie-Pierre Revel, Philippe Soyer
Summary: AI has been widely applied in thoracic oncology, including pulmonary nodule detection, segmentation, characterization, and stratification. Some of the tools developed have already been commercially available.
JAPANESE JOURNAL OF RADIOLOGY
(2023)
Review
Oncology
Conrad B. Falkson, Emily T. Vella, Peter M. Ellis, Donna E. Maziak, Yee C. Ung, Edward Yu
Summary: This systematic review evaluated treatment options for patients with thymic epithelial tumors and found that postoperative radiotherapy provides overall survival benefits for patients with thymic carcinoma and thymoma, especially those at high risk. Chemotherapy also showed efficacy for thymic carcinoma and thymoma, but results for neoadjuvant chemotherapy and minimally invasive surgical techniques may be affected by selection bias. Further large-scale prospective studies are needed to control confounders.
JOURNAL OF THORACIC ONCOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Constance de Margerie-Mellon, Guillaume Chassagnon
Summary: Artificial intelligence has been applied in medical imaging, specifically in the detection, segmentation, and classification of lung nodules, as well as the characterization and prognosis prediction of lung cancer. However, the clinical implementation of AI tools is still in its early stages due to the lack of generalizability in published studies, limited understanding of the working mechanism, and insufficient data on the impact on radiologists' decision-making and patient outcomes.
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2023)
Article
Oncology
Clara Vigneron, Othmane Laousy, Guillaume Chassagnon, Maria Vakalopoulou, Julien Charpentier, Jerome Alexandre, Matthieu Jamme, Frederic Pene
Summary: This study evaluated the impact of daily activities, nutritional status, and muscle surface on the prognosis of critically ill cancer patients in the intensive care unit (ICU). The results showed that muscle surface, the ability to perform daily activities, and the six-month course of nutritional parameters could predict short- and long-term prognosis. This information is crucial for solid cancer patients with life-threatening complications.
Article
Health Care Sciences & Services
Pasquale Varriale, Borna Mueller, Gregory Katz, Lorraine Dallas, Alfonso Aguaron, Marion Azoulai, Nicolas Girard
Summary: The study aimed to assess the relative importance of different aspects of lung cancer care and explore the disease burden, including socioeconomic aspects not commonly covered. The findings revealed that end-of-life care and physical well-being were rated highest by patients, but communication about end-of-life care with healthcare professionals was lacking. Additionally, employment and income were significantly impacted.
JMIR FORMATIVE RESEARCH
(2023)
Correction
Multidisciplinary Sciences
Joowon Chung, Doyun Kim, Jongmun Choi, Sehyo Yune, Kyoung Doo Song, Seonkyoung Kim, Michelle Chua, Marc D. Succi, John Conklin, Maria G. Figueiro Longo, Jeanne B. Ackman, Milena Petranovic, Michael H. Lev, Synho Do
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Liisa L. Bergmann, Jeanne B. Ackman, Jitka Starekova, Alexander Moeller, Scott Reeder, Scott K. Nagle, Mark L. Schiebler
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA
(2023)
Article
Rheumatology
Carole Jalaber, Xavier Puechal, Ines Saab, Emma Canniff, Benjamin Terrier, Luc Mouthon, Eglantine Cabanne, Sandra Mghaieth, Marie-Pierre Revel, Guillaume Chassagnon
Summary: Chest CT can differentiate between GPA and RP, with subglottic tracheal involvement and extensive airway involvement being the most relevant features.
ARTHRITIS RESEARCH & THERAPY
(2022)