The Warburg effect and tumour immune microenvironment in extramammary Paget's disease: overexpression of lactate dehydrogenase A correlates with immune resistance

Hypoxia accelerates the progression of angiosarcoma through the regulation of angiosarcoma cells and tumor microenvironment

(2019) Saki Maeda-Otsuka et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Accumulation of exhausted CD8+ T cells in extramammary Paget’s disease

(2019) Natsuko Iga et al.   PLoS One

Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy

(2019) Mauzo et al.   Cancers

Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades

(2019) Michelle K. Y. Siu et al.   Cancers

PD-L1 Detection—Pearls and Pitfalls Associated With Current Methodologies Focusing on Entities Relevant to Dermatopathology

(2019) Kei Shing Oh et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Expression of CD3, PD-L1 and CTLA-4 in mammary and extra-mammary Paget disease

(2018) Georgia Karpathiou et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

(2016) Almut Brand et al.   Cell Metabolism

Tumor-associated macrophages in skin: How to treat their heterogeneity and plasticity

(2016) Taku Fujimura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance

(2016) Susana Romero-Garcia et al.   Frontiers in Immunology

Molecular Pathways: Targeting Cellular Energy Metabolism in Cancer via Inhibition of SLC2A1 and LDHA

(2015) A. T. Ooi et al.   CLINICAL CANCER RESEARCH

Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer

(2015) Jian Wang et al.   Oncotarget

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma

(2014) Hala Girgis et al.   Molecular Cancer

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Comparison of Foxp3+ Regulatory T cells and CD163+ Macrophages in Invasive and Non-invasive Extramammary Paget’s Disease

(2013) T Fujimura et al.   ACTA DERMATO-VENEREOLOGICA

Clinical significance of macrophage heterogeneity in human malignant tumors

(2013) Yoshihiro Komohara et al.   CANCER SCIENCE

Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?

(2013) Stephen Yiu Chuen Choi et al.   JOURNAL OF PATHOLOGY

Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma

(2012) Shi L. Sheng et al.   FEBS Journal

Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma

(2010) Horlad Hasita et al.   CANCER SCIENCE

FOXP3+ regulatory T-cells are abundant in vulvar Paget's disease and are associated with recurrence

(2010) Joshua Z. Press et al.   GYNECOLOGIC ONCOLOGY

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

(2009) David G. DeNardo et al.   CANCER CELL

Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins

(2009) Liqing Zhuang et al.   MODERN PATHOLOGY

Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells

(2009) Olivier Feron   RADIOTHERAPY AND ONCOLOGY