Cellular and Molecular Mechanisms of Kidney Injury in 2,8-Dihydroxyadenine Nephropathy

A Diagnosis for All Rare Genetic Diseases: The Horizon and the Next Frontiers

(2019) Kym M. Boycott et al.   CELL

A novel approach to adenine-induced chronic kidney disease associated anemia in rodents

(2018) Asadur Rahman et al.   PLoS One

Roles of Macrophage Exosomes in Immune Response to Calcium Oxalate Monohydrate Crystals

(2018) Nilubon Singhto et al.   Frontiers in Immunology

Chronic tubulointerstitial kidney disease in untreated adenine phosphoribosyl transferase (APRT) deficiency: A case report


(2018) Benjamin Cochran et al.   CLINICAL NEPHROLOGY

Long-term renal outcomes of APRT deficiency presenting in childhood

(2018) Hrafnhildur Linnet Runolfsdottir et al.   PEDIATRIC NEPHROLOGY

Crystal nephropathies: mechanisms of crystal-induced kidney injury

(2017) Shrikant R. Mulay et al.   Nature Reviews Nephrology

Adenine-induced chronic kidney disease in rats

(2017) Vishal Diwan et al.   NEPHROLOGY

Kidney Disease in Adenine Phosphoribosyltransferase Deficiency

(2016) Hrafnhildur Linnet Runolfsdottir et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Quantitative UPLC–MS/MS assay of urinary 2,8-dihydroxyadenine for diagnosis and management of adenine phosphoribosyltransferase deficiency

(2016) Margret Thorsteinsdottir et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease

(2016) Shrikant R. Mulay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of PDGF-D in healthy and fibrotic kidneys

(2016) Eva M. Buhl et al.   KIDNEY INTERNATIONAL

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

(2016) Isis Ludwig-Portugall et al.   KIDNEY INTERNATIONAL

Crystallopathies

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis

(2016) Shrikant R. Mulay et al.   Nature Communications

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74

(2015) S. Djudjaj et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Recurrent 2,8-Dihydroxyadenine Nephropathy: A Rare but Preventable Cause of Renal Allograft Failure

(2014) M. Zaidan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Dendritic cells and macrophages in the kidney: a spectrum of good and evil

(2014) Natasha M. Rogers et al.   Nature Reviews Nephrology

Mesenchymal Stem Cells from Rats with Chronic Kidney Disease Exhibit Premature Senescence and Loss of Regenerative Potential

(2014) Barbara Mara Klinkhammer et al.   PLoS One

A New Equation to Estimate Glomerular Filtration Rate

(2013) Andrew S. Levey et al.   ANNALS OF INTERNAL MEDICINE

An APRT mutation is strongly associated with and likely causative for 2,8-dihydroxyadenine urolithiasis in dogs

(2013) Eva Furrow et al.   MOLECULAR GENETICS AND METABOLISM

CD44-Deficiency Attenuates the Immunologic Responses to LPS and Delays the Onset of Endotoxic Shock-Induced Renal Inflammation and Dysfunction

(2013) Elena Rampanelli et al.   PLoS One

Adenine-induced chronic kidney and cardiovascular damage in rats

(2013) Vishal Diwan et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Crystalline Nephropathies

(2012) Leal C. Herlitz et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Adenine Phosphoribosyltransferase Deficiency

(2012) G. Bollee et al.   Clinical Journal of the American Society of Nephrology

Anti-Inflammatory Role of Fetuin-A in Injury and Infection

(2012) H. Wang et al.   CURRENT MOLECULAR MEDICINE

2,8-dihydroxyadenine uroliths in a dog

(2012) Doreen M. Houston et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Kidney injury molecule-1: More than just an injury marker of tubular epithelial cells?

(2012) Ai Ing Lim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

(2012) Shrikant R. Mulay et al.   JOURNAL OF CLINICAL INVESTIGATION

Prognostic assessment of estimated glomerular filtration rate by the new Chronic Kidney Disease Epidemiology Collaboration equation in comparison with the Modification of Diet in Renal Disease Study equation

(2011) Hicham Skali et al.   AMERICAN HEART JOURNAL

Fetuin-A Regulation of Calcified Matrix Metabolism

(2011) Willi Jahnen-Dechent et al.   CIRCULATION RESEARCH

Histopathological patterns of nephrocalcinosis: a phosphate type can be distinguished from a calcium type

(2011) T. Wiech et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Pivotal Role of Toll-Like Receptors 2 and 4, Its Adaptor Molecule MyD88, and Inflammasome Complex in Experimental Tubule-Interstitial Nephritis

(2011) Matheus Correa-Costa et al.   PLoS One

Establishment of Acute Kidney Injury Mouse Model by 0.75% Adenine Ingestion

(2011) Yoshiyuki Morishita et al.   RENAL FAILURE

CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia

(2010) Gerritje J.W. van der Windt et al.   AMERICAN JOURNAL OF PATHOLOGY

Phenotype and Genotype Characterization of Adenine Phosphoribosyltransferase Deficiency

(2010) G. Bollee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy

(2010) Yoko Oyama et al.   LABORATORY INVESTIGATION

Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization

(2010) Carson K. Lam et al.   NATURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model

(2009) Mizuho Tamura et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Mechanisms of uric acid crystal-mediated autoinflammation

(2009) Fabio Martinon   IMMUNOLOGICAL REVIEWS

CD44 Deficiency Is Associated with Enhanced Escherichia coli-Induced Proinflammatory Cytokine and Chemokine Release by Peritoneal Macrophages

(2009) G. J. W. van der Windt et al.   INFECTION AND IMMUNITY

Kidney injury molecule-1 in renal disease

(2009) Femke Waanders et al.   JOURNAL OF PATHOLOGY

New Equations to Estimate GFR in Children with CKD

(2009) G. J. Schwartz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Nephrocalcinosis: new insights into mechanisms and consequences

(2009) B. A. Vervaet et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Recent advances in the pathophysiology of nephrolithiasis

(2008) Khashayar Sakhaee   KIDNEY INTERNATIONAL

An active renal crystal clearance mechanism in rat and man

(2008) Benjamin A. Vervaet et al.   KIDNEY INTERNATIONAL