Article
Microbiology
Xuejiao Yin, Chunhui Duan, Shoukun Ji, Peizhi Tian, Sisi Ju, Hui Yan, Yingjie Zhang, Yueqin Liu
Summary: This study investigated whether lambs with high and low average daily gain (ADG) have different rumen and rectum microbial communities. The results showed potential relationships between rumen and rectum microbiota and ADG in weaned lambs. Furthermore, the study identified specific bacterial biomarkers in the rumen and rectum that are associated with ADG using linear discriminant analysis effect size (LEfSe) analysis.
Article
Agriculture, Dairy & Animal Science
Federico Correa, Diana Luise, Ivonne Archetti, Paolo Bosi, Paolo Trevisi
Summary: This study aimed to evaluate the short-term effect of oral administration of nucleotides before and after weaning on growth performance, health, development of the intestinal immunity and microbiome of piglet. Nucleotide supplementation did not influence the growth performance of piglets but may have expressed a positive effect on pig microbiota anticipating its maturation at weaning, with possible immunostimulant activity on the intestinal immune system. Nucleotides are essential for the development of the gastrointestinal tract and immune function, but their intake with milk by piglets could be insufficient.
Article
Agriculture, Multidisciplinary
Yangzheng He, Yong Sun, Jing Li, Xiaoyu Peng, Wei Li, Yu Gao, Jiaqi Wang, Xinggang Ni, Lina Pan, Zeyuan Deng
Summary: This study aimed to investigate the impact of human milk fat substitutes (HMFS) on lipid metabolism in first-weaned Sprague Dawley rats. The findings showed that HMFS administration did not affect body weight but significantly decreased body fat content. Lipidome analysis revealed changes in glycerophospholipid levels in the liver of HMFS-fed rats. Furthermore, HMFS administration promoted lipid metabolism in the rat liver at both the gene and protein levels.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Yangzheng He, Yong Sun, Jing Li, Xiaoyu Peng, Wei Li, Yu Gao, Jiaqi Wang, Xinggang Ni, Lina Pan, Zeyuan Deng
Summary: Although formula-fed infants are more prone to obesity than breastfed ones, this study found that administering human milk fat substitutes (HMFS) did not affect body weight in rats, but significantly decreased body fat content. The study also revealed the potential mechanism by which HMFS affects body fat buildup and promotes lipid metabolism in the liver. These findings underscore the nutritional benefits of HMFS for infants.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Dairy & Animal Science
Lijun Shang, Junyan Zhou, Jiayu Tu, Xiangfang Zeng, Shiyan Qiao
Summary: Research has shown that supplementation with Microcin C7 (C7) can improve growth performance and reduce diarrhea rates in weaned piglets. The selective regulation of specific microbial taxa by C7 contributes to its diarrhea-alleviating effects. The optimal dosage range for C7 is 250-500 mg/kg, with supplementation of 5000 mg/kg showing no adverse effects on any parameters, making it a safe alternative to antibiotic growth promoters.
Article
Agriculture, Dairy & Animal Science
Lei Hou, Li Wang, Yueqin Qiu, YunXia Xiong, Hao Xiao, Hongbo Yi, Xiaolu Wen, Zeling Lin, Zhikang Wang, Xuefen Yang, Zongyong Jiang
Summary: Protein restriction and subsequent realimentation in weaned piglets lead to compensatory growth and protein deposition, while also influencing gut microbiota and metabolite profiles to improve intestinal health.
Article
Microbiology
Wenxia Qin, Zhendong Yu, Zhechang Li, Hengfeng Liu, Wei Li, Jianan Zhao, Yin Ren, Libao Ma
Summary: Early weaning is effective in improving the utilization rate of sows in pig farms. The combination of berberine and ellagic acid can improve the growth performance and intestinal damage in weaned piglets by altering gut microbiota composition and short-chain fatty acids.
Article
Microbiology
Sandrine Dufourny, Nadine Antoine, Elena Pitchugina, Veronique Delcenserie, Stephane Godbout, Caroline Douny, Marie-Louise Scippo, Eric Froidmont, Pierre Rondia, Jose Wavreille, Nadia Everaert
Summary: The study found that the addition of apple pomace feed has a beneficial effect on the growth performance, intestinal morphology, and microbiota of weaned piglets, with the 4% inclusion level showing the most promising results.
Article
Agriculture, Dairy & Animal Science
Yang Liu, Md. Abul Kalam Azad, Sujuan Ding, Qian Zhu, Francois Blachier, Zugong Yu, Haijun Gao, Xiangfeng Kong
Summary: This study investigated the effects of dietary bile acid (BA) supplementation on the growth performance and colonic development, function, microbiota, and metabolites in piglets with normal birth weight (NBW) and intrauterine growth retardation (IUGR). The results showed that BA supplementation increased colon length and weight, decreased plasma DAO concentration in NBW piglets, and decreased plasma concentrations of D-lactate and endotoxin and colonic DAO and endotoxin in IUGR piglets. Additionally, BA supplementation increased the abundance of potentially beneficial bacteria and metabolites, and upregulated the expressions of antioxidative and immune-related genes in colonic mucosa.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
J-M Zhang, X-Y Liu, W. Gu, H-Y Xu, H-C Jiao, J-P Zhao, X-J Wang, H-F Li, H. Lin
Summary: Probiotics can improve body weight and feed intake in broiler chickens, increase SCFAs content, and activate FFAR2/3 expression; while antibiotics may introduce pathogenic bacteria, leading to decreased SCFAs concentration and compromised immune system.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Infectious Diseases
Mohammad Moniruzzaman, Hunhwan Kim, Haewon Shin, Hyunsoo Kim, Nayoung Kim, Sungyeon Chin, Adhimoolam Karthikeyan, Hyojick Choi, Gonsup Kim, Taesun Min
Summary: The results of the study demonstrate that dietary supplementation of curcumin nanospheres can significantly improve the growth performance and feed utilization of weaned piglets, reduce total cholesterol levels, and decrease fecal coliform bacteria and ammonia gas emissions.
Article
Agriculture, Multidisciplinary
Lei Hou, Shuting Cao, Yueqin Qiu, YunXia Xiong, Hao Xiao, Xiaolu Wen, Xuefen Yang, Kaiguo Gao, Li Wang, Zongyong Jiang
Summary: The study evaluated the effects of sub-therapeutic antibiotics on piglets' body tissue deposition, gut microbiota, and metabolite profiles. Results showed that STA did not improve growth performance and altered microbial composition and metabolites, leading to a rebound of pathogenic bacteria.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Agriculture, Dairy & Animal Science
Min Song, Fenglin Zhang, Lin Chen, Qiang Yang, Han Su, Xiaohua Yang, Haiwen He, Mingfa Ling, Jisong Zheng, Chen Duan, Xumin Lai, Mushui Pan, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
Summary: CDCA supplementation improved the growth performance of weaned piglets by enhancing intestinal morphology and barrier function, enhancing lipid digestion, altering serum metabolic profiles, and changing the relative abundance of certain gut bacteria.
Article
Veterinary Sciences
Robin B. Guevarra, Eun Sol Kim, Jin Ho Cho, Minho Song, Jae Hyoung Cho, Jun Hyung Lee, Hyeri Kim, Sheena Kim, Gi Beom Keum, Chan Ho Lee, Won Tak Cho, Suphot Watthanaphansak, Hyeun Bum Kim
Summary: This study evaluated the effects of probiotics, prebiotics, and their synbiotic combination on gut microbiota in weaned piglets. The results showed that they all improved intestinal health in the piglets by modulating the gut microbiota.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Microbiology
Francesco Strati, Meritxell Pujolassos, Claudia Burrello, Maria Rita Giuffre, Georgia Lattanzi, Flavio Caprioli, Jacopo Troisi, Federica Facciotti
Summary: Different antibiotic treatments influence the gut microbiota's ability to control intestinal inflammation by altering the microbial community structure and production of metabolites, as observed in experimental colitis models.
Article
Biochemistry & Molecular Biology
Yunhan Liu, Bin Huo, Zhongping Chen, Kun Wang, Lingjie Huang, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, Yong Zhuo, Caimei Wu, De Wu, Zhengfeng Fang
Summary: This study investigated the effects of chromium yeast on the growth performance, carcass characteristics, meat traits, antioxidant status, immune traits, and serum biochemical parameters of grow-finish pigs. The results showed that chromium yeast supplementation improved the meat quality and immune traits of pigs and increased their antioxidant capacity.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Jianping Wang, Xuemei Ding, Qiufeng Zeng, Shiping Bai, Keying Zhang, Xiangbing Mao, Shengyu Xu, Yong Zhuo, Yue Xuan, Huanwei Peng, Jingbo Liu, Huadong Yin
Summary: This study investigated the effects of 25-hydroxyvitamin D (25OHD) on egg production, egg quality, immune response, and intestinal health of laying hens challenged with Escherichia coli lipopolysaccharide (LPS). The results showed that supplementing 80 mg/kg of 25OHD in diets can improve egg laying rate and feed efficiency, decrease broken egg rate, and enhance intestinal barrier function and antioxidant capacity. Additionally, it can also decrease proinflammatory cytokines levels in laying hens. Therefore, the addition of 25OHD in diets may enhance laying performance and egg quality in LPS-challenged hens.
Article
Microbiology
Yalei Liu, Xinlin Jia, Junlei Chang, Xuemei Jiang, Lianqiang Che, Yan Lin, Yong Zhuo, Bin Feng, Zhengfeng Fang, Jian Li, Lun Hua, Jianping Wang, Zhihua Ren, Mengmeng Sun, De Wu, Shengyu Xu
Summary: The study found that maternal addition of yeast cultures had a significant effect on the growth performance and intestinal microorganisms of weaned piglets, but did not improve their antioxidant performance.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Qiong Deng, Ye Du, Zhu Wang, Yeda Chen, Jieyan Wang, Hui Liang, Du Zhang
Summary: This study aimed to establish a DNAm-driven gene-based prognostic model for ccRCC. RRBS was performed on ccRCC patients' DNA extracts to screen candidate CpG sites. The study identified the role of hypermethylation in ccRCC and discovered potential biomarkers for early diagnosis and prognosis evaluation.
Article
Microbiology
Qibing Wang, Yang Zhao, Lei Guo, Xiangyuan Ma, Yi Yang, Yong Zhuo, Xuemei Jiang, Lun Hua, Lianqiang Che, Shengyu Xu, Bin Feng, Zhengfeng Fang, Jian Li, Yan Lin, De Wu
Summary: This study aimed to investigate the effects of XOS supplementation on growth performance, gut morphology, SCFA production, and gut microbiota of weaned piglets. The results showed that a high plant-based protein diet aggravated diarrhea in weaned piglets, while XOS supplementation alleviated it. Additionally, XOS improved nutrient digestibility, protected intestinal morphology, and optimized the gut flora.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Yan Lin, Dan Li, Zhao Ma, Lianqiang Che, Bin Feng, Zhengfeng Fang, Shengyu Xu, Yong Zhuo, Jian Li, Lun Hua, De Wu, Junjie Zhang, Yuanxiao Wang
Summary: This study found that supplementation of tributyrin in the diet of sows improved reproductive performance by shortening the parturition time and reducing the diarrhea rate in piglets. It also increased the levels of fat and protein in the milk. Furthermore, tributyrin supplementation positively affected the gut microbiota composition and immune systems of piglets and sows.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Shuang Li, Jie Zheng, Jiaqi He, Hao Liu, Yingyan Huang, Liansu Huang, Ke Wang, Xilun Zhao, Bin Feng, Lianqiang Che, Zhengfeng Fang, Jian Li, Shengyu Xu, Yan Lin, Xuemei Jiang, Lun Hua, Yong Zhuo, De Wu
Summary: This study found that a high-fiber diet can increase the feed intake of sows during lactation. The mechanism behind this effect is believed to be the modulation of gut microbiota. Adding high-fiber feed to the gestation diet can improve the lactational feed intake of sows by increasing the abundance of beneficial bacteria.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Fangyuan Chen, Lunxiang Yang, Li Zhe, Maamer Jlali, Yong Zhuo, Xuemei Jiang, Lingjie Huang, Fali Wu, Ruinan Zhang, Shengyu Xu, Yan Lin, Lianqiang Che, Bin Feng, De Wu, Aurelie Preynat, Zhengfeng Fang
Summary: The supplementation of multi-carbohydrase and phytase can improve digestibility and nutrient utilization in fattening pigs, leading to increased growth rate and feed efficiency. These findings have important implications for cost-saving, minimizing nutrient waste, and improving swine production efficiency.
Article
Agriculture, Dairy & Animal Science
Yuwei Zhang, Qiang Zhou, Shiya Liu, Xiang Quan, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, De Wu, Lianqiang Che
Summary: The study found that partially substituting whey protein concentrate with spray-dried porcine plasma in milk replacer for neonatal piglets can improve growth performance and intestinal morphology, increase digestive enzyme activity, and reduce pathogenic bacteria.
Article
Biochemistry & Molecular Biology
Guangrong Xie, Qipeng Zhang, Zhengfeng Fang, Lianqiang Che, Yan Lin, Shengyu Xu, Yong Zhuo, Lun Hua, Xuemei Jiang, Jian Li, Mengmeng Sun, Yuanfeng Zou, Chao Huang, Lixia Li, De Wu, Bin Feng
Summary: This study found that excessive intake of oxidized fat during pregnancy and lactation can harm both the mother's body and the health of their offspring. However, supplementation of vitamin D and inulin during pregnancy and lactation can mitigate these damages.
Review
Microbiology
Feng Qin, Wenyan Wei, Junjie Gao, Xuemei Jiang, Lianqiang Che, Zhengfeng Fang, Yan Lin, Bin Feng, Yong Zhuo, Lun Hua, Jianping Wang, Mengmeng Sun, De Wu, Shengyu Xu
Summary: Dietary fiber is a substance that cannot be digested by endogenous digestive enzymes but can be digested by intestinal microorganisms. In recent years, it has gained increasing attention due to its functional properties, potential health benefits to animals, and fermentability. Research suggests that dietary fiber can provide energy for pigs through intestinal microbial fermentation, improve sow welfare and reproductive performance, regulate intestinal flora, and enhance immunity.
Article
Agriculture, Dairy & Animal Science
Ya Wang, Guowei Li, Xiangyuan Ma, Shengyu Xu, Yan Lin, Lun Hua, Jian Li, Bin Feng, Zhengfeng Fang, Xuemei Jiang, Yong Zhuo, Lianqiang Che, De Wu
Summary: This experiment aimed to determine the chemical composition and nutrient digestibility of six extruded full fat soybean samples from different sources in non-gestating, gestating, and lactating sows. The results showed that extruded full fat soybean can be used as a high-quality energy ingredient in sow diets with high DE and ME values. This work provides accurate nutritional value parameters for extruded full fat soybean to guide its rational use in sow diets.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Yang Liu, Aimin Wu, Ruixia Mo, Qiang Zhou, Lianghui Song, Zheng Li, Hua Zhao, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, De Wu, Lianqiang Che
Summary: This study investigated the effects of dietary lysolecithin supplementation on the growth performance, nutrients absorption, lipid metabolism, and redox status of weaned pigs. The results showed that dietary lysolecithin supplementation improved the growth performance, enhanced nutrients absorption, and improved the redox status and lipid metabolism of weaned pigs.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Xinyu Wang, Jun Huang, Huan Li, Yanlong Li, Shuang Cai, Bangxin Xue, Zhekun Zhu, Xiangzhou Zeng, Xiangfang Zeng
Summary: Embryo development plays a crucial role in pregnancy outcome and lifelong health. A high throughput screening cell model was established to select nutrients that can enhance embryonic development. Resveratrol was identified as a potential candidate for promoting embryo development.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ren Yoshitomi, Motofumi Kumazoe, Kwan-Woo Lee, Yuki Marugame, Yoshinori Fujimura, Hirofumi Tachibana
Summary: This study investigated the connection between food components and circular RNA (circRNA), as well as the regulatory effect of (-)-Epigallocatechin-3-O-gallate (EGCG) on circRNA expression in the liver. The results showed that EGCG treatment altered the expression of circRNAs in mice livers, and one upregulated circRNA (mmu_circRNA_011775) affected the expression of genes related to liver fibrosis and the cardiovascular system.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
ViVi Tang Kang Wee, Hitoshi Shirakawa, Sung-Ling Yeh, Chiu-Li Yeh
Summary: This study investigated the effects of fermented rice bran (FRB) on modulating intestinal aryl hydrocarbon receptor (AhR) expression, innate lymphoid cell (ILC)3 populations, the fecal microbiota distribution, and their associations with dextran sodium sulfate (DSS)-induced acute colitis. The results showed that FRB supplementation can improve gut health, alleviate colitis symptoms, and have anti-colitis effects by enhancing ILC3 and AhR functions.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xinzhuang Ma, Xijuan Ren, Xuemin Zhang, Guangyin Wang, Hui Liu, Li Wang
Summary: The study demonstrates that rutin can ameliorate kidney damage caused by PFOA exposure by improving oxidative stress and regulating lipid metabolism.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ya-Jie Ding, Xue-Ning Li, Zhe Xiao, Chen-Yang Li, Li-Hong Jia
Summary: This study investigates the impact of maternal vitamin D levels during pregnancy on infantile eczema. The findings suggest that lower prenatal maternal vitamin D levels increase the risk of eczema in infants aged 0-1 year. Furthermore, the study indicates that infants with eczema have lower expression of the Foxp3 gene in cord blood and decreased placental FOXP3 protein expression. These results suggest that vitamin D may affect the development of infantile eczema through the regulation of gene and protein expression in cord blood and placenta.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Shujing Liu, Shiyu Song, Shuan Wang, Tonghui Cai, Lian Qin, Xinzhuang Wang, Guangming Zhu, Haibo Wang, Wenqi Yang, Chunlu Fang, Yuan Wei, Fu Zhou, Yang Yu, Shaozhang Lin, Shuang Peng, Liangming Li
Summary: Long-term consumption of a high-fat diet disrupts energy balance and leads to weight gain. The fat mass and obesity-associated (FTO) gene is involved in high-fat diet-induced obesity. The hypothalamus plays a crucial role in regulating energy balance, and high-fat diet-induced hypothalamic leptin resistance contributes to obesity. The study reveals that FTO is associated with hypothalamic leptin resistance and provides new insight into its role in obesity.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Liu, Xiaoling Chen, Jun He, Yuheng Luo, Ping Zheng, Bing Yu, Daiwen Chen, Zhiqing Huang
Summary: This study found that oleanolic acid promotes the transformation of fast muscle fibers to slow muscle fibers through the TGR5-mediated CaN/NFATc1 signaling pathway.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Huijuan Hu, Fan Li, Shaoli Cheng, Tingting Qu, Fanqi Shen, Jie Cheng, Lina Chen, Zhenghang Zhao, Hao Hu
Summary: Long-term alternate-day fasting can ameliorate obesity-induced anxiety-like behavior and hippocampal damage, but it can cause anxiety in normal-weight mice. Short-term alternate-day fasting does not produce adverse emotional reactions in normal-weight mice.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Jannis Ulke, Christian Schwedler, Janine Krueger, Vanessa Stein, Peter Geserick, Andre Kleinridders, Kai Kappert
Summary: This study characterized the glycosylation pattern of PTPRJ in the liver and found that high-fat diet-induced obesity altered the glycosylation pattern of PTPRJ. These findings provide new insights into the role of glycosylation in metabolic disorders.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Liu, Marii Mochizuki, Yasuyuki Suzuki, Erika Takemasa, Akiko Yano, Matome Imai, Masaki Mogi
Summary: This study evaluated the feasibility and efficacy of leucine supplementation in offsetting immune dysfunction in sarcopenia. The results showed that leucine supplementation not only improved muscle mass and restored mitochondrial respiratory function, but also reduced inflammation levels. These findings are important for the rational design and optimization of leucine supplementation in patients with sarcopenia and autoimmune diseases.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Review
Biochemistry & Molecular Biology
Zhan Su, Jun Fang, Bin Yao, Gang Liu
Summary: Osteoporosis is a serious skeletal disorder that can be prevented and treated by polyphenols, which have antioxidant and anti-allergy properties. Polyphenols affect bone metabolism and density by inhibiting oxidative stress and exhibiting antibacterial effects. This article provides an overview of the preventive and therapeutic effects of polyphenols on osteoporosis and discusses the mechanisms involved.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Qian Zhang, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Tong Wang, Xiaojing Wang
Summary: Maternal high-fat diet can affect the structure and function of offspring's pancreas, leading to weight gain, glucose metabolism disorders, and insulin secretion defects. The study found that this may be related to DNA methylation of specific genes in the pancreas.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Hanaa Mousa, Aisha Al Saei, Rozaimi Mohamad Razali, Susu M. Zughaier
Summary: Vitamin D deficiency and dyslipidemia have significant implications for human health. This study investigates the proteomic profiles of individuals with and without these conditions, revealing decreased HDL-associated apolipoproteins and increased acute-phase proteins. Pathway analysis highlights inflammatory and cancer pathways associated with vitamin D deficiency and dyslipidemia.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Qi-Lan Jiang, Tao Li, Qin Xu, Yang Zeng, Wei Wang, Bo-Tao Zhang, Qing-Ping Yao, Rui Jiang, Jun Jiang
Summary: Environmental factors, especially dietary habits, play a significant role in the susceptibility and progression of cardiovascular diseases through epigenetic modification. This study found that a methyl donor diet can attenuate balloon injury-induced intimal hyperplasia in rat carotid arteries, potentially by influencing the composition and function of the extracellular matrix.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Review
Biochemistry & Molecular Biology
Jiayi Cai, Yajie Qiao, Lingbin Chen, Youguang Lu, Dali Zheng
Summary: The Notch signaling pathway plays a regulatory role in normal biological processes such as cellular differentiation, apoptosis, and stem cell self-renewal. Dysregulation of this pathway is associated with various types of cancer. Natural products targeting the Notch pathway have shown potential as chemopreventive and anti-cancer agents, providing a feasible solution to fight against cancer by either alone or in combination with current therapeutic agents.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)