Ampakine pretreatment enables a single brief hypoxic episode to evoke phrenic motor facilitation

Averting Opioid-induced Respiratory Depression without Affecting Analgesia

(2018) Albert Dahan et al.   ANESTHESIOLOGY

Effects of chronic systemic low-impact ampakine treatment on neurotrophin expression in rat brain

(2018) Daniel P. Radin et al.   BIOMEDICINE & PHARMACOTHERAPY

Respiratory neuroplasticity – Overview, significance and future directions

(2017) David D. Fuller et al.   EXPERIMENTAL NEUROLOGY

Intermittent Hypoxia Enhances Functional Connectivity of Mid-Cervical Spinal Interneurons

(2017) K.A. Streeter et al.   JOURNAL OF NEUROSCIENCE

Intermittent but not sustained moderate hypoxia elicits long-term facilitation of hypoglossal motor output

(2017) Julia E.R. Wilkerson et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Pharmacological modulation of hypoxia-induced respiratory neuroplasticity

(2017) Sara Turner et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Acute ampakine treatment ameliorates age-related deficits in long-term potentiation

(2016) Daniel P. Radin et al.   BIOMEDICINE & PHARMACOTHERAPY

Ampakine CX717 potentiates intermittent hypoxia-induced hypoglossal long-term facilitation

(2016) S. M. Turner et al.   JOURNAL OF NEUROPHYSIOLOGY

Repetitive acute intermittent hypoxia increases growth/neurotrophic factor expression in non-respiratory motor neurons

(2016) I. Satriotomo et al.   NEUROSCIENCE

Ampakines Enhance Weak Endogenous Respiratory Drive and Alleviate Apnea in Perinatal Rats

(2015) Jun Ren et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Stimulation of Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease by Ampakines

(2015) Mai K. ElMallah et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tetraplegia is associated with enhanced peripheral chemoreflex sensitivity and ventilatory long-term facilitation

(2015) Abdulghani Sankari et al.   JOURNAL OF APPLIED PHYSIOLOGY

Intermittent hypoxia and neurorehabilitation

(2015) Elisa J. Gonzalez-Rothi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Therapeutic potential of intermittent hypoxia: a matter of dose

(2014) Angela Navarrete-Opazo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Ventilatory Long-Term Facilitation in Humans

(2014) Nicole J. Tester et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Coadministration of the AMPAKINE CX717 with Propofol Reduces Respiratory Depression and Fatal Apneas

(2013) Jun Ren et al.   ANESTHESIOLOGY

Hypoxia-induced phrenic long-term facilitation: emergent properties

(2013) Michael J. Devinney et al.   Annals of the New York Academy of Sciences

Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717

(2012) Jun Ren et al.   JOURNAL OF APPLIED PHYSIOLOGY

Phrenic long-term facilitation after acute intermittent hypoxia requires spinal ERK activation but not TrkB synthesis

(2012) M. S. Hoffman et al.   JOURNAL OF APPLIED PHYSIOLOGY

Ampakines promote spine actin polymerization, long-term potentiation, and learning in a mouse model of Angelman syndrome

(2012) Michel Baudry et al.   NEUROBIOLOGY OF DISEASE

Acute sleep deprivation: the effects of the AMPAKINE compound CX717 on human cognitive performance, alertness and recovery sleep

(2011) Julia Boyle et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Serotonin 2A and 2B receptor-induced phrenic motor facilitation: differential requirement for spinal NADPH oxidase activity

(2011) P.M. MacFarlane et al.   NEUROSCIENCE

BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats

(2010) Enikö A. Kramár et al.   NEUROBIOLOGY OF AGING

Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice

(2010) Danielle A. Simmons et al.   NEUROBIOLOGY OF DISEASE

Opiate-Induced Suppression of Rat Hypoglossal Motoneuron Activity and Its Reversal by Ampakine Therapy

(2010) Amanda R. Lorier et al.   PLoS One

Ampakine CX717 Protects against Fentanyl-induced Respiratory Depression and Lethal Apnea in Rats

(2009) Jun Ren et al.   ANESTHESIOLOGY

Selective Antagonism of Opioid-Induced Ventilatory Depression by an Ampakine Molecule in Humans Without Loss of Opioid Analgesia

(2009) B G Oertel et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Daily intermittent hypoxia augments spinal BDNF levels, ERK phosphorylation and respiratory long-term facilitation

(2009) Julia E.R. Wilkerson et al.   EXPERIMENTAL NEUROLOGY

Neural deficits contribute to respiratory insufficiency in Pompe disease

(2009) L. R. DeRuisseau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

(2009) D. A. Simmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ampakine therapy to counter fentanyl-induced respiratory depression

(2009) John J. Greer et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Role of the brain-derived neurotrophic factor at glutamatergic synapses

(2007) A L Carvalho et al.   BRITISH JOURNAL OF PHARMACOLOGY