Stimulation of Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease by Ampakines

Neither serotonin nor adenosine-dependent mechanisms preserve ventilatory capacity in ALS rats

(2014) N.L. Nichols et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Polysomnographic findings in infantile Pompe disease

(2013) Sujay Kansagra et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Coadministration of the AMPAKINE CX717 with Propofol Reduces Respiratory Depression and Fatal Apneas

(2013) Jun Ren et al.   ANESTHESIOLOGY

Phase I/II Trial of Adeno-Associated Virus–Mediated Alpha-Glucosidase Gene Therapy to the Diaphragm for Chronic Respiratory Failure in Pompe Disease: Initial Safety and Ventilatory Outcomes

(2013) Barbara K. Smith et al.   HUMAN GENE THERAPY

Intrapleural Administration of AAV9 Improves Neural and Cardiorespiratory Function in Pompe Disease

(2013) Darin J Falk et al.   MOLECULAR THERAPY

Sustained Correction of Motoneuron Histopathology Following Intramuscular Delivery of AAV in Pompe Mice

(2013) Mai K ElMallah et al.   MOLECULAR THERAPY

The respiratory neuromuscular system in Pompe disease

(2013) David D. Fuller et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Intermittent Hypoxia and Stem Cell Implants Preserve Breathing Capacity in a Rodent Model of Amyotrophic Lateral Sclerosis

(2012) Nicole L. Nichols et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717

(2012) Jun Ren et al.   JOURNAL OF APPLIED PHYSIOLOGY

Enzyme replacement therapy in late-onset Pompe disease: a systematic literature review

(2012) Antonio Toscano et al.   JOURNAL OF NEUROLOGY

Pompe disease gene therapy

(2011) B. J. Byrne et al.   HUMAN MOLECULAR GENETICS

Acute sleep deprivation: the effects of the AMPAKINE compound CX717 on human cognitive performance, alertness and recovery sleep

(2011) Julia Boyle et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Pompe disease: Design, methodology, and early findings from the Pompe Registry

(2011) Barry J. Byrne et al.   MOLECULAR GENETICS AND METABOLISM

Recombinant human acid alpha-glucosidase (rhGAA) in adult patients with severe respiratory failure due to Pompe disease

(2011) David Orlikowski et al.   NEUROMUSCULAR DISORDERS

Hypoglossal Neuropathology and Respiratory Activity in Pompe Mice

(2011) Kun-Ze Lee et al.   Frontiers in Physiology

A Randomized Study of Alglucosidase Alfa in Late-Onset Pompe's Disease

(2010) Ans T. van der Ploeg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Progression of Neuromuscular Findings in Infantile Pompe Disease

(2010) T. Andrew Burrow et al.   PEDIATRIC NEUROLOGY

Opiate-Induced Suppression of Rat Hypoglossal Motoneuron Activity and Its Reversal by Ampakine Therapy

(2010) Amanda R. Lorier et al.   PLoS One

Alglucosidase alfa: Long term use in the treatment of patients with Pompe disease

(2010) Michael Beck   Therapeutics and Clinical Risk Management

Ampakine CX717 Protects against Fentanyl-induced Respiratory Depression and Lethal Apnea in Rats

(2009) Jun Ren et al.   ANESTHESIOLOGY

Selective Antagonism of Opioid-Induced Ventilatory Depression by an Ampakine Molecule in Humans Without Loss of Opioid Analgesia

(2009) B G Oertel et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Temporal Neuropathologic and Behavioral Phenotype of 6neo/6neoPompe Disease Mice

(2009) Richard L. Sidman et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Phrenic Motoneuron Discharge Patterns During Hypoxia-Induced Short-Term Potentiation in Rats

(2009) Kun-Ze Lee et al.   JOURNAL OF NEUROPHYSIOLOGY

Neural deficits contribute to respiratory insufficiency in Pompe disease

(2009) L. R. DeRuisseau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pompe disease: A neuromuscular disease with respiratory muscle involvement

(2009) Uwe Mellies et al.   RESPIRATORY MEDICINE

Central Respiratory Rhythmogenesis Is Abnormal in Lbx1- Deficient Mice

(2008) S. Pagliardini et al.   JOURNAL OF NEUROSCIENCE