Chronic dry eye induced corneal hypersensitivity, neuroinflammatory responses, and synaptic plasticity in the mouse trigeminal brainstem

Interaction between astrocytic colony stimulating factor and its receptor on microglia mediates central sensitization and behavioral hypersensitivity in chronic post ischemic pain model

(2018) Yuying Tang et al.   BRAIN BEHAVIOR AND IMMUNITY

Reduced intraepithelial corneal nerve density and sensitivity accompany desiccating stress and aging in C57BL/6 mice

(2018) Mary Ann Stepp et al.   EXPERIMENTAL EYE RESEARCH

Proinflammatory Markers, Chemokines, and Enkephalin in Patients Suffering from Dry Eye Disease

(2018) Pierre Nicolle et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury

(2018) Norikazu Kiguchi et al.   Journal of Neuroinflammation

Neuropathic pain and dry eye

(2018) Anat Galor et al.   Ocular Surface

A new dry eye mouse model produced by exorbital and intraorbital lacrimal gland excision

(2018) Katsuhiko Shinomiya et al.   Scientific Reports

Effects of corneal injury on ciliary nerve fibre activity and corneal nociception in mice: A behavioural and electrophysiological study

(2018) Fanny Joubert et al.   EUROPEAN JOURNAL OF PAIN

Dual enkephalinase inhibitor PL265

(2018) Annabelle Reaux-Le Goazigo et al.   PAIN

Reconsidering the central role of mucins in dry eye and ocular surface diseases

(2018) Christophe Baudouin et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Characteristics of Ocular Pain Complaints in Patients With Idiopathic Dry Eye Symptoms

(2017) Jerry P. Kalangara et al.   Eye & Contact Lens-Science and Clinical Practice

Macrophages in trigeminal ganglion contribute to ectopic mechanical hypersensitivity following inferior alveolar nerve injury in rats

(2017) Dulguun Batbold et al.   Journal of Neuroinflammation

Evidence that dry eye represents a chronic overlapping pain condition

(2017) Alexandra E Levitt et al.   Molecular Pain

TFOS DEWS II Report Executive Summary

(2017) Jennifer P. Craig et al.   Ocular Surface

Corneal Nerve and Epithelial Cell Alterations in Corneal Allodynia: An In Vivo Confocal Microscopy Case Series

(2017) Pedram Hamrah et al.   Ocular Surface

In Vivo Confocal Microscopy of Corneal Nerves in Health and Disease

(2017) Andrea Cruzat et al.   Ocular Surface

TFOS DEWS II pain and sensation report

(2017) Carlos Belmonte et al.   Ocular Surface

Inflammation in Dry Eye Disease

(2017) Michelle K. Rhee et al.   OPHTHALMOLOGY

Ocular inflammation induces trigeminal pain, peripheral and central neuroinflammatory mechanisms

(2016) Pierre-Serge Launay et al.   NEUROBIOLOGY OF DISEASE

Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease

(2016) Illés Kovács et al.   PAIN

Orofacial Neuropathic Pain Leads to a Hyporesponsive Barrel Cortex with Enhanced Structural Synaptic Plasticity

(2016) Karine Thibault et al.   PLoS One

Understanding Neuropathic Corneal Pain—Gaps and Current Therapeutic Approaches

(2016) Sunali Goyal et al.   Seminars in Ophthalmology

Ocular neuropathic pain

(2015) Perry Rosenthal et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Combined 3DISCO clearing method, retrograde tracer and ultramicroscopy to map corneal neurons in a whole adult mouse trigeminal ganglion

(2015) Pierre-Serge Launay et al.   EXPERIMENTAL EYE RESEARCH

Opioid and chemokine receptor crosstalk: a promising target for pain therapy?

(2015) Stéphane Mélik Parsadaniantz et al.   NATURE REVIEWS NEUROSCIENCE

Sensitization of trigeminal brainstem pathways in a model for tear deficient dry eye

(2015) Mostafeezur Rahman et al.   PAIN

Extraorbital Lacrimal Gland Excision

(2014) William Stevenson et al.   CORNEA

Pathologic role of glial nitric oxide in adult and pediatric neuroinflammatory diseases

(2014) Mehdi Ghasemi et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Lacrimal gland removal impairs sexual behavior in mice

(2014) Rosa Maria Cavaliere et al.   Frontiers in Neuroanatomy

Neuroinflammation and the generation of neuropathic pain

(2013) A Ellis et al.   BRITISH JOURNAL OF ANAESTHESIA

In VivoConfocal Microscopy of the Ocular Surface: From Bench to Bedside

(2013) Edoardo Villani et al.   CURRENT EYE RESEARCH

The development of chronic pain: physiological CHANGE necessitates a multidisciplinary approach to treatment

(2013) Joseph Pergolizzi et al.   CURRENT MEDICAL RESEARCH AND OPINION

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells

(2013) Masayuki Kurose et al.   JOURNAL OF NEUROPHYSIOLOGY

Mechanisms Involved in Injury and Repair of the Murine lacrimal Gland: Role of Programmed Cell Death and Mesenchymal Stem Cells

(2012) Driss Zoukhri   Ocular Surface

The mechanisms of microgliosis and pain following peripheral nerve injury

(2011) Margarita Calvo et al.   EXPERIMENTAL NEUROLOGY

Corneal Alternations Induced by Topical Application of Benzalkonium Chloride in Rabbit

(2011) Wensheng Chen et al.   PLoS One

Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea

(2010) Andrés Parra et al.   NATURE MEDICINE

Coding of facial expressions of pain in the laboratory mouse

(2010) Dale J Langford et al.   NATURE METHODS

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride

(2008) H Liang et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Time course of ocular surface and lacrimal gland changes in a new scopolamine-induced dry eye model

(2008) Sabrina Viau et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1 , Interleukin-6, and Tumor Necrosis Factor-  in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

(2008) Y. Kawasaki et al.   JOURNAL OF NEUROSCIENCE