Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells

Corneal dry-responsive neurons in the spinal trigeminal nucleus respond to innocuous cooling in the rat

(2013) Masayuki Kurose et al.   JOURNAL OF NEUROPHYSIOLOGY

Efficacy of Topical Blockade of Interleukin-1 in Experimental Dry Eye Disease

(2012) Andre Okanobo et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Dry Eye Disease

(2012) William Stevenson   ARCHIVES OF OPHTHALMOLOGY

Assessment of chronic trigeminal neuropathic pain by the orofacial operant test in rats

(2012) Myeounghoon Cha et al.   BEHAVIOURAL BRAIN RESEARCH

Direct inhibition of the cold-activated TRPM8 ion channel by Gαq

(2012) Xuming Zhang et al.   NATURE CELL BIOLOGY

Topical hindpaw application of L-menthol decreases responsiveness to heat with biphasic effects on cold sensitivity of rat lumbar dorsal horn neurons

(2012) A.H. Klein et al.   NEUROSCIENCE

Characterization of bilateral trigeminal constriction injury using an operant facial pain assay

(2012) H.L. Rossi et al.   NEUROSCIENCE

Change in Prostaglandin Expression Levels and Synthesizing Activities in Dry Eye Disease

(2012) Jongwoo Shim et al.   OPHTHALMOLOGY

Selenium Compound Protects Corneal Epithelium against Oxidative Stress

(2012) Akihiro Higuchi et al.   PLoS One

Alterations of Tear Neuromediators in Dry Eye Disease

(2011) Alessandro Lambiase   ARCHIVES OF OPHTHALMOLOGY

TRPM8 acute desensitization is mediated by calmodulin and requires PIP2: distinction from tachyphylaxis

(2011) Ignacio Sarria et al.   JOURNAL OF NEUROPHYSIOLOGY

Characterizing the Spontaneous Blink Generator: An Animal Model

(2011) J. Kaminer et al.   JOURNAL OF NEUROSCIENCE

Decrease in phosphatidylinositol 4,5-bisphosphate levels mediates desensitization of the cold sensor TRPM8 channels

(2011) Yevgen Yudin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of TRPM8 channel activity

(2011) Yevgen Yudin et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Topical application of l-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats

(2010) Amanda H. Klein et al.   BEHAVIOURAL BRAIN RESEARCH

Menthol Response and Adaptation in Nociceptive-Like and Nonnociceptive-Like Neurons: Role of Protein Kinases

(2010) Ignacio Sarria et al.   Molecular Pain

Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea

(2010) Andrés Parra et al.   NATURE MEDICINE

Altered thermal sensitivity in neurons injured by infraorbital nerve lesion

(2010) Damaris Schmid et al.   NEUROSCIENCE LETTERS

Selenoprotein P Controls Oxidative Stress in Cornea

(2010) Akihiro Higuchi et al.   PLoS One

Dry eye in 2008

(2009) Mark B Abelson et al.   CURRENT OPINION IN OPHTHALMOLOGY

Corneal epithelial proliferation and thickness in a mouse model of dry eye

(2009) Claudia Fabiani et al.   EXPERIMENTAL EYE RESEARCH

Neural regulation of lacrimal gland secretory processes: Relevance in dry eye diseases

(2009) Darlene A. Dartt   PROGRESS IN RETINAL AND EYE RESEARCH

Excitation and sensitization of nociceptors by bradykinin: what do we know?

(2009) Kazue Mizumura et al.   EXPERIMENTAL BRAIN RESEARCH

Activity of the Neuronal Cold Sensor TRPM8 Is Regulated by Phospholipase C via the Phospholipid Phosphoinositol 4,5-Bisphosphate

(2008) Richard L. Daniels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY