Article
Biochemistry & Molecular Biology
Ana Ciric, Dorde Medarevic, Bojan Calija, Vladimir Dobricic, Milena Rmandic, Tanja Barudzija, Andelija Malenovic, Ljiljana Djekic
Summary: The entrapment procedure of a poorly water soluble drug was studied to investigate its effect on the physicochemical and drug release performances of chitosan/xanthan polyelectrolyte complexes (PECs). Different drug entrapment procedures and chitosan-to-xanthan mass ratios were observed to affect the formation of PECs, leading to controlled drug release with zero-order kinetics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Khadijatul Kobra, Siew Yee Wong, Mohammad A. Jafar Mazumder, Xu Li, M. Tarik Arafat
Summary: In this study, a potential controlled topical delivery vehicle was explored using olive oil nanoemulsion modified with xanthan gum and gum acacia. The modified formulations showed improved drug release and antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Aftab Alam, Talha Jawaid, Saud M. Alsanad, Mehnaz Kamal, Pinki Rawat, Vinita Singh, Pravej Alam, Prawez Alam
Summary: This study developed a transdermal nanoformulation for Proteus vulgaris using hesperidin, which showed good drug release and antimicrobial activity. It could be an advanced approach for treating Proteus vulgaris infections.
Article
Biochemistry & Molecular Biology
Fatih Ozbas, Elif Tuzun, Ahmet Yildiz, Selcan Karakus
Summary: An optimized method was developed for the synthesis of biological macromolecule blend supported iron oxide nanoparticles in this study. The synthesized nanoparticles were characterized and optimized to determine the effect of the biopolymer blend matrix on morphology, size, stability, and thermal properties. Optimization analysis confirmed that sonication played a role in size distribution and stability of nanoparticles with the optimum mixture ratio of the binary biopolymer matrix.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Environmental Sciences
Subhraseema Das, Ganeswar Dalei
Summary: In this study, Schiff-base controlled release fertilizer (CRF) hydrogels composed of dialdehyde xanthan gum (DAXG) and gelatin were fabricated through a simple in situ crosslinking reaction. Increasing the content of DAXG in the hydrogels resulted in a compact network structure. Phytotoxic assay indicated that the hydrogels were non-toxic to different plants. The hydrogels exhibited good water-retention behavior in soil and remained reusable even after 5 cycles. The release of urea from the hydrogels followed a controlled release profile influenced by macromolecular relaxation. Growth assays on Abelmoschus esculentus (Okra) plant provided an intuitive evaluation on the performance of the CRF hydrogel in terms of growth and water-holding capacity. This study demonstrated a facile method for preparing CRF hydrogels to improve urea utilization and soil moisture retention.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Ana Ciric, Jelena Milinkovic Budincic, Dorde Medarevic, Vladimir Dobricic, Milena Rmandic, Tanja Barudzija, Andelija Malenovic, Lidija Petrovic, Ljiljana Djekic
Summary: This study investigated the influence of escin content and drying method on the formation, physicochemical properties, and controlled drug release of chitosan/xanthan gum-based polyelectrolyte complexes (PECs). The results showed that the mass ratio of escin to polymers and the drying method affected the properties of the PECs, with ambient-dried PECs having higher yield, entrapment efficiency, and escin content compared to spray-dried ones.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Selcan Karakus, Ezgi Tan, Merve Ilgar, Yesim Muge Sahin, Demet Sezgin Mansuroglu, Deniz Ismik, Razium Ali Somroo, Ayben Kilislioglu
Summary: This study investigated the effect of the polymer matrix on drug delivery systems by synthesizing active-drug-loaded XaG/ZnO nanoparticles. Various characterization techniques were used, and the results showed that the nanoparticles released the drug with the Higuchi model. Comparisons of viscosity and parameters revealed that XaG/ZnO nanoparticles synthesized by ultrasonic irritation method are an optimal formulation for drug delivery.
Article
Chemistry, Applied
Wei Zhou, Zhen Cai, Rui Zhang, Kun Hu, Fangfang Wu, Yong Hu, Chao Huang, Yun Chen
Summary: In this study, nanoparticles were prepared by compositing cationic starch (CS) and xanthan gum (XG) for the first time. The physicochemical properties, micromorphology, and emulsification properties of CS/XG nanoparticles were measured. The results showed that the composite nanoparticles had increased size and excellent storage and thermal properties. The study also demonstrated that the prepared emulsions had environmental responsiveness.
Article
Chemistry, Applied
Jwala Patel, Sabyasachi Maiti, N. S. Hari Narayana Moorthy
Summary: In this study, repaglinide-loaded hydrogel particles were successfully fabricated using carboxyethyl xanthan gum and carboxymethyl xanthan gum. The controlled drug delivery performance of these particles was evaluated, and it was found that acetylated hydrogel particles exhibited high drug entrapment efficiency and extended drug release, which could effectively control diabetes.
CARBOHYDRATE POLYMERS
(2022)
Article
Energy & Fuels
Akinleye O. Sowunmi, Vincent E. Efeovbokhan, Oyinkepreye D. Orodu, Babalola A. Oni
Summary: The study compared the EOR performance of Gum Arabic (GA) and Xanthan Gum (XG) solutions, showing similar oil recovery for 1.0 wt% GA and 0.1 wt% XG polymeric solutions. GA exhibited Newtonian viscosity at high shear rates. The impact of nano-polymeric solutions on oil recovery was found to be higher than that of polymeric solutions.
JOURNAL OF PETROLEUM EXPLORATION AND PRODUCTION TECHNOLOGY
(2022)
Article
Agronomy
Fengjiao Hao, Xiaohui Liu, Huizhu Yuan, Xiaojing Yan, Daibin Yang
Summary: The study prepared four controlled-release granular formulations of pymetrozine based on kaolin and xanthan gum or calcined kaolin and xanthan gum. Different 3D networks were formed in the granular formulations, leading to varying water uptake rates and release rates of pymetrozine. Pymetrozine release rate was positively correlated with water uptake capacity, and diffusion was found to be the dominant mechanism for release. Incorporating pymetrozine in controlled-release granules alleviated phytotoxicity and showed significant control effects on rice planthoppers. A granule with an intermediate release rate of pymetrozine was found to be more suitable for long-term control of paddy planthoppers.
PEST MANAGEMENT SCIENCE
(2022)
Article
Environmental Sciences
Iheb Bouzid, Julien Maire, Fabien Laurent, Mathias Broquaire, Nicolas Fatin-Rouge
Summary: Xanthan gels were studied for controlling the reductive dechlorination of HCHs and TCBs in a high permeability contrast and fast sedimentary aquifer, showing excellent transmission of alkalinity and persistent blocking effect. The use of Ca(OH)(2) suspension in xanthan solution demonstrated the feasibility of alkaline dechlorination kinetics, converting HCHs into TCBs.
ENVIRONMENTAL POLLUTION
(2021)
Article
Materials Science, Multidisciplinary
U. J. Martin-Camacho, M. Torres-Ramos, J. A. Sanchez-Burgos, A. Perez-Larios
Summary: In this study, a drug delivery system was designed by encapsulating functionalized TCE nanoparticles on a PLGA matrix. The TCE nanoparticles showed improved optical absorption, energy, surface functional groups, and size compared to pure TiO2 nanoparticles. The drug delivery system demonstrated controlled and sustained release under simulated physiological conditions, with the release mechanism determined as Fickian diffusion.
Review
Pharmacology & Pharmacy
Ilker S. Bayer
Summary: Polysaccharides are complex molecules with exceptional properties and can be chemically modified. They have increased application in drug encapsulation and release in nanoscale synthesis due to their biocompatibility and biodegradability. This review focuses on studying sustained drug release from nanoscale polysaccharides, particularly drug release kinetics and mathematical modeling. It highlights the importance of modeling in predicting the behavior of specific polysaccharide matrices and reducing experimental trial and error.
Review
Pharmacology & Pharmacy
Anna Froelich, Emilia Jakubowska, Barbara Jadach, Piotr Gadzinski, Tomasz Osmalek
Summary: This article provides a summary of the recent studies on polysaccharide compounds obtained from natural sources, and their potential as drug carriers. These compounds are biocompatible, biodegradable, and sensitive to degradation by the colon microbiome, making them attractive for pharmaceutical applications. The article focuses on the formulation and application of micro- and nanoparticles derived from gums and their blends with other polymers.
Article
Environmental Sciences
Jagdeep Singh, A. S. Dhaliwal
ENVIRONMENTAL TECHNOLOGY
(2020)
Article
Engineering, Environmental
Jagdeep Singh, A. S. Dhaliwal
Summary: A novel nanocomposite adsorbent containing silver nanoparticles (AgNPs) was synthesized for the efficient removal of Methylene blue (MB) dye from aqueous phase. The characterization of the nanocomposite showed stable formation of AgNPs inside the polymer matrix with an average size of 100 nm. The adsorption capacity was improved and the kinetics and isotherm models indicated favorable adsorption behavior, making the nanocomposite a promising adsorbent for MB dye removal from liquid phase.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Materials Science, Ceramics
Ankit Kumar, Pravin Kumar, A. S. Dhaliwal
Summary: By studying the phase evolution of calcium-doped zirconia after sintering at 1400 degrees C, it was found that with increasing calcium doping, the cubic phase in zirconia develops and achieves near-total stabilization at 16 mol-% doping of calcium. The findings were validated through microstructure and elemental analyses, as well as Raman spectroscopic studies, indicating potential applications in new technology such as oxygen sensors and solid electrolytes.
ADVANCES IN APPLIED CERAMICS
(2021)
Article
Chemistry, Multidisciplinary
Jagdeep Singh, A. S. Dhaliwal
Summary: In this study, a facile method of electrochemical and photocatalytic degradation of MB dye using eco-friendly nanocomposites based on reduced graphene oxide/silver nanowires (rGO/AgNWs) was demonstrated. The synthesized nanocomposite was characterized by various analytical techniques and it was found that the rGO/AgNWs with 9.5 wt% Ag content showed the highest degradation efficiency for both electrochemical and photocatalytic degradation.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2022)
Article
Materials Science, Ceramics
Ankit Kumar, Pravin Kumar, A. S. Dhaliwal
Summary: The phase evolution of calcium-doped zirconia has been studied at various sintering temperatures, revealing the stabilization of the monoclinic and cubic phases. With increasing sintering temperature, the development of the cubic phase is observed, ultimately achieving a fully stabilized cubic phase at 1400 degrees C. The presence of calcium is uniformly distributed in the samples, and the calcium-stabilized zirconia shows good thermal stability and higher hardness compared to pure zirconia.
JOURNAL OF THE KOREAN CERAMIC SOCIETY
(2022)
Article
Crystallography
Ankit Kumar, Pravin Kumar, A. S. Dhaliwal
Summary: This study investigated the phase transformations and morphological properties of homogeneous zirconia thin films, with a thickness of 250 nm, synthesized on silicon substrate. Despite the amorphous nature of the deposited films, it was observed that a phase transformation from cubic phase to monoclinic phase occurred in the temperature range of 600-800 degrees C. The results also showed that the grain size of zirconia increased with the increase in annealing temperature.
Article
Environmental Sciences
J. Singh, A. S. Dhaliwal
Summary: This paper reports the microwave-assisted green synthesis of a mesoporous adsorbent decorated with silver nanoparticles (AgNPs) on reduced graphene oxide (rGO) for the effective removal of two basic dyes. The use of extract of Ocimum tenuiflorum as a reducing agent not only reduces the graphene oxide and Ag+ ions, but also prevents the agglomeration of rGO sheets. Various characterization techniques were employed to study the crystallinity, chemical composition, surface morphology, and specific surface area of the synthesized nanocomposite. The results reveal the suitability of the pseudo-second-order kinetics and Langmuir isotherm model for the adsorption of the dyes, with maximum adsorption capacities of 970 mg/g for Methylene blue and 900 mg/g for Rhodamine B dye. The higher adsorption capacity is attributed to the synergetic effect of AgNPs, higher surface area, and higher zeta potential of the rGO/AgNPs nanocomposite. Furthermore, the synthesized nanocomposite exhibits excellent reusability after multiple uses. Therefore, the rGO/AgNPs nanocomposite may prove to be a noble adsorbent for the removal of basic dye from aqueous solutions.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Ankit Kumar, S. K. Singh, Pravin Kumar, A. S. Dhaliwal
Summary: Phase transformations in zirconia thin films induced by ion-beam irradiation have been studied. The structural and morphological properties of the films were modified after irradiation with different fluences. For the as-deposited film, an amorphous phase transformed into a cubic phase with increasing fluence, while for the annealed film, a fraction of cubic phase transformed into a monoclinic phase with increasing fluence. Surface features, such as grain agglomeration and grain boundary diffusion, were observed with increasing fluence.
JOURNAL OF MATERIALS RESEARCH
(2022)
Article
Chemistry, Physical
Karan Bansal, Jagdeep Singh, A. S. Dhaliwal
Summary: Silver-decorated nanocomposite based on reduced graphene oxide was successfully synthesized using leaf extract of Azadirachta indica as a reducing agent. The properties of the synthesized Ag/rGO nanocomposite, including its structure, surface morphology, and electrochemical performance, were studied using various analytical techniques. The presence of phytochemicals in the leaf extract that played a role in the in-situ formation of AgNPs and reduction of GO into rGO was confirmed through FTIR analysis.
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
(2023)
Article
Chemistry, Inorganic & Nuclear
Karan Bansal, Jagdeep Singh, A. S. Dhaliwal
Summary: The present work focuses on the in-situ synthesis of Fe3O4/rGO magnetic nanocomposite using the leaf extract of Azadirachta indica as a reducing agent. The study demonstrates the effective cooperation between rGO array and Fe3O4 nanoparticles. The synthesized nanocomposite shows high crystallinity, strong Fe-O stretching bonding, tunable energy bandgap, superparamagnetic nature, and high thermal stability, making it a potential material for advanced applications.
INORGANIC AND NANO-METAL CHEMISTRY
(2023)
Proceedings Paper
Materials Science, Multidisciplinary
Sachin Kumar, A. S. Dhaliwal
MATERIALS TODAY-PROCEEDINGS
(2020)
Article
Pharmacology & Pharmacy
Xueliang Xiu, Shichao Ma, Zhiyong Li, Zhipeng Li, Xuemei Li, Yangtao Ruan, Dezhao Li, Jianwei Wang, Fengsen Ma
Summary: Liposomes are promising delivery vehicles for drugs and vaccines. The use of microfluidic chips for liposome preparation is an effective method. However, traditional liposome preparation technologies hinder their industrial production and clinical application. This study presents a novel three-dimensional integrated microfluidic device for continuous liposome preparation and purification, which shows potential for industrial production of nano-pharmaceutical applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2024)
