4.6 Editorial Material

Schizophrenia genetics moves into the light

Journal

BRITISH JOURNAL OF PSYCHIATRY
Volume 209, Issue 2, Pages 93-94

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ROYAL COLLEGE OF PSYCHIATRISTS
DOI: 10.1192/bjp.bp.116.185405

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Two recent reports convincingly demonstrate that the risk of schizophrenia is influenced by common variation of C4, which codes for complement component 4, and by rare, disruptive mutations of SETD1A, which codes for a histone methylase. These important results open the way for major advances in our understanding of the fundamental biological processes leading to disease.

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