EGCG regulates CTR1 expression through its pro‐oxidative property in non‐small‐cell lung cancer cells

LncRNA NEAT1/let-7a-5p axis regulates the cisplatin resistance in nasopharyngeal carcinoma by targeting Rsf-1 and modulating the Ras-MAPK pathway

(2018) Fei Liu et al.   CANCER BIOLOGY & THERAPY

The long non-coding RNA NEAT1 contributes to extracellular matrix degradation in degenerative human nucleus pulposus cells

(2018) Zhi Ruan et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Metformin Promotes HaCaT Cell Apoptosis through Generation of Reactive Oxygen Species via Raf-1-ERK1/2-Nrf2 Inactivation

(2018) Xiaoyan Wang et al.   INFLAMMATION

Gambogic acid-induced autophagy in nonsmall cell lung cancer NCI-H441 cells through a reactive oxygen species pathway

(2018) Shujun Wang et al.   Journal of Cancer Research and Therapeutics

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative

(2018) José Teixeira et al.   TOXICOLOGY

Reactive Oxygen Species: Involvement in T Cell Signaling and Metabolism

(2018) Davide G. Franchina et al.   TRENDS IN IMMUNOLOGY

LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation

(2018) E. Zulato et al.   BIOCHEMICAL PHARMACOLOGY

EGCG inhibits CSC-like properties through targeting miR-485/CD44 axis in A549-cisplatin resistant cells

(2018) Pan Jiang et al.   MOLECULAR CARCINOGENESIS

The Effect of Ultrasound, Oxygen and Sunlight on the Stability of (−)-Epigallocatechin Gallate

(2018) Jiajun Zeng et al.   MOLECULES

The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response

(2018) S. Mohammad Lellahi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells

(2018) Maiara de S. Oliveira et al.   Redox Biology

Long Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors

(2018) Peixin Dong et al.   Frontiers in Genetics

Dietary Intervention by Phytochemicals and Their Role in Modulating Coding and Non-Coding Genes in Cancer

(2017) Liviuta Budisan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells

(2017) A L Schroyer et al.   ONCOGENE

Sodium fluoride induces apoptosis in mouse splenocytes by activating ROS-dependent NF-κB signaling

(2017) Huidan Deng et al.   Oncotarget

Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo

(2017) Nils Blüthgen et al.   Scientific Reports

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells

(2016) Pan Jiang et al.   Oncotarget

Cancer Therapy by Catechins Involves Redox Cycling of Copper Ions and Generation of Reactive Oxygen Species

(2016) Mohd Farhan et al.   Toxins

Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG

(2015) María Isabel Cerezo-Guisado et al.   FOOD AND CHEMICAL TOXICOLOGY

Mechanism of Dose-Dependent Regulation of UBE1L by Polyphenols in Human Bronchial Epithelial Cells

(2015) Apei Jiang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea

(2015) Chung S. Yang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Roles of oxidative stress and the ERK1/2, PTEN and p70S6K signaling pathways in arsenite-induced autophagy

(2015) Ya-Chun Huang et al.   TOXICOLOGY LETTERS

EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer

(2015) Xuemin Wang et al.   PLoS One

Oxidative Stress Induces Biphasic ERK1/2 Activation in the RPE with Distinct Effects on Cell Survival at Early and Late Activation

(2014) Stefan Koinzer et al.   CURRENT EYE RESEARCH

Reactive Oxygen Species (ROS) Inducible DNA Cross-Linking Agents and Their Effect on Cancer Cells and Normal Lymphocytes

(2014) Wenbing Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

EGCG Enhances the Efficacy of Cisplatin by Downregulating hsa-miR-98-5p in NSCLC A549 Cells

(2014) Dong-Hu Zhou et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Inhibition of Catalase by Tea Catechins in Free and Cellular State: A Biophysical Approach

(2014) Sandip Pal et al.   PLoS One

New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate

(2014) Hae-Suk Kim et al.   Redox Biology

Selective death of cancer cells by preferential induction of reactive oxygen species in response to (-)-epigallocatechin-3-gallate

(2012) Na Young Min et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Changes in intracellular redox status influence multidrug resistance in gastric adenocarcinoma cells

(2012) DE-JUN TAI et al.   Experimental and Therapeutic Medicine

Hydrogen Peroxide Inducible DNA Cross-Linking Agents: Targeted Anticancer Prodrugs

(2011) Yunyan Kuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regulation of reactive oxygen species generation in cell signaling

(2011) Yun Soo Bae et al.   MOLECULES AND CELLS

Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC

(2010) Alex Chang   LUNG CANCER

Is Glutathione the Major Cellular Target of Cisplatin? A Study of the Interactions of Cisplatin with Cancer Cell Extracts

(2009) Yonit Kasherman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Elevated Glutathione Levels Confer Cellular Sensitization to Cisplatin Toxicity by Up-Regulation of Copper Transporter hCtr1

(2008) H. H. W. Chen et al.   MOLECULAR PHARMACOLOGY

Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells

(2007) Joan Villena et al.   FREE RADICAL BIOLOGY AND MEDICINE